BioTech 365

OCTOBER 16, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Plant genetic engineering to fight hidden hunger.More than 2 billion people worldwide suffer from micronutrient malnutrition due to deficiencies in minerals and vitamins.

Genetic Engineering 40

Genetic Engineering Engineer Genetics Development 40

Advarra

JUNE 12, 2023

Gene therapy research is exciting and full of promise, but because of the risks involved, it’s also highly regulated, requiring an institutional biosafety committee (IBC) to provide additional oversight and risk assessment. IRBs are tasked with protecting research subject’s rights and welfare. What Does an IBC Review?

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Genetic Engineering Gene Therapy Genetics Engineer 98

BioTech 365

AUGUST 24, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Genetically engineered good bacteria could aid in combating disease.Our bodies are home to several bacterial species that help us maintain our health and wellbeing.

Genetic Engineering 40

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BioTech 365

DECEMBER 23, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Genetic engineering without unwanted side effects helps fight parasites.Modified CRISPR-Cas9 gene editing scissors are enabling researchers at the University of Zurich to make alterations to the genetic … Continue reading (..)

Genetic Engineering 40

Genetic Engineering Engineer Genetics Gene Editing 40

Scienmag

DECEMBER 3, 2020

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

Genetic Engineering 40

Genetic Engineering Engineer Genetics Bacteria 40

BioPharma Reporter

SEPTEMBER 28, 2021

A new deal sees Bone Therapeutics gain access to iPSC derived, genetically engineered MSCs.

Genetic Engineering 72

Genetic Engineering Engineer Genetics Research 72

Medical Xpress

DECEMBER 5, 2022

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

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Protein Genetic Engineering Research Engineer 75

BioTech 365

SEPTEMBER 27, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Taking the guesswork out of genetic engineering: STAMPScreen pipeline helps streamline genetic studies in mammalian cell.Today’s genetic engineers have a plethora of resources at their disposal: an … Continue reading (..)

Genetic Engineering 40

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Advarra

MARCH 31, 2023

The use of engineered genetic materials in clinical trials is rapidly expanding, with potential applications for genetic vaccines, gene-modified cellular therapies, and gene therapies. A key part of the IBC’s evaluation is assessing the risks posed by the engineered genetic materials.

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Engineer Genetics Clinical Research Research 52

Scienmag

JULY 6, 2022

Researchers have solved a medical mystery in a poorly understood disease by uncovering which cells cause tumours in patients with tuberous sclerosis complex (TSC). As described in Cell Reports, they did this by creating genetically engineered kidney organoids, or “mini-kidneys” grown from human tissue.

Genetic Engineering 73

Genetic Engineering Engineer Genetics Research 73

Scienmag

SEPTEMBER 10, 2021

Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases.

Genetics 59

Genetics Genetic Engineering Engineer Research 59

Pharmaceutical Technology

FEBRUARY 15, 2023

To obtain human antibody responses within a mouse, mice are genetically engineered to be humanised for their Ig genes. KO-plus-transgenic humanisation involves generating genetically engineered (HumAb) mice by disrupting the endogenous mouse Ig genes and simultaneously introducing human Ig transgenes at a different and random location.

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Gene Expression Gene Genetic Engineering Antibody 130

Pharmaceutical Technology

JUNE 4, 2023

To further understand the key themes and technologies disrupting the pharmaceutical industry, access GlobalData’s latest thematic research report on Pharmaceutical. Pfizer and Biogen stand in second and third positions, respectively.

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BioTech 365

APRIL 21, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: International research team argues for combination of organic farming and genetic engineering.For more sustainability on a global level, EU legislation should be changed to allow the use … Continue reading →

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Scienmag

MARCH 19, 2021

Treatment involving a single injection has long-lasting effects BOSTON – Researchers have used a genetic engineering strategy to dramatically reduce levels of tau–a key protein that accumulates and becomes tangled in the brain during the development of Alzheimer’s disease–in an animal model of the condition.

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Genetic Engineering Gene Therapy Gene Engineer 66

Scienmag

SEPTEMBER 8, 2020

Credit: Avalos Lab/Princeton University Researchers at Princeton University have created a new and improved way to more precisely control genetically engineered bacteria: by simply switching the lights on and off. Working in E.

Bacteria 56

Bacteria Genetic Engineering Engineer Genetics 56

Scienmag

OCTOBER 14, 2020

Scientists prove cell-cultured meat products can offer enhanced nutrition compared to conventionally produced meat A group of researchers at Tufts University have genetically engineered cow muscle cells to produce plant nutrients not natively found in beef cells.

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Engineer Genetic Engineering Genetics Scientist 40

Scienmag

DECEMBER 21, 2020

Credit: Agricultural Research Service-USDA.

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Scienmag

MARCH 5, 2021

Researchers develop tunable system that harnesses the spread of cargo carried by gene drives Credit: Gerard Terradas, UC San Diego Powerful new genetic engineering methods have given scientists the potential to revolutionize several sectors of global urgency.

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pharmaphorum

NOVEMBER 1, 2021

Delytact (teserpaturev) is a genetically engineered oncolytic herpes simplex virus type 1 (HSV-1) that was approved for marketing in Japan earlier this year, and received pricing approval in August at 1.43 million yen (around $12,500) per dose, according to a Pharma Japan report.

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Scienmag

APRIL 27, 2021

First-of-its-kind advance holds promise for making new strides in research, treatments Irvine, Calif., April 27, 2021 — University of California, Irvine biologists have developed a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer’s disease.

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Genetic Engineering Genetics Engineer Development 51

Velocity Clinical Research

OCTOBER 3, 2024

As Nick Spittal states in this Advarra press release, membership in the Gene Therapy Ready (GTR) site network “allows Velocity to start studies over a month faster and provides a meaningful credential and important validation that increases sponsors’ confidence in our specialized capabilities to conduct complex clinical research safely.”

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Gene Therapy Gene Genetic Engineering Clinical Research 52

Advarra

AUGUST 8, 2023

Gene therapy research is booming in the clinical setting. In this blog, we summarize the growth, risks, and regulatory requirements for gene therapy research. We also discuss how a centralized biosafety review process can benefit this type of research.

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Gene Therapy Gene Research Genetics 52

Pharmaceutical Technology

FEBRUARY 15, 2023

Innovation S-curve for the pharmaceutical industry Gene splicing using nucleases is a key innovation area in the pharmaceutical industry Nucleases play a fundamental role in the field of recombinant DNA technology, or genetic engineering. Nucleases are enzymes that hydrolytically cleave the phosphodiester backbone of DNA.

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WCG Clinical

AUGUST 27, 2024

The NIH Guidelines also stipulate that at least two members of each IBC come from the surrounding community and be unaffiliated with the institution where the research is occurring apart from their membership on the IBC. Many of those original concerns of the 1970s and 1980s surrounding genetic engineering have lessened over time.

Genetic Engineering 52

Genetic Engineering Engineer Compliance Genetics 52

pharmaphorum

DECEMBER 24, 2020

The US National Institutes of Health said that the research it had co-funded used AI to transform a bacterial protein into a new research tool. It was led by researchers in the lab of Dr Lin Tian, principal investigator at the University of California Davis School of Medicine.

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Development Drugs Protein Genetic Engineering 77

XTalks

JULY 31, 2020

According to studies conducted by researchers at Cincinnati Children’s Hospital, the bacteria can help heal damaged intestinal tissues. The study developed and researched microbe-controlled and genetically-engineered mice to understand the healing response in the intestine when receiving specific signals from bacteria.

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Bacteria Genetic Engineering Engineer Research 98

BioTech 365

FEBRUARY 5, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Can a miniscule worm hold the secret to genetically reversing brain damage? A team of Hebrew University researchers have successfully used genetic engineering as a first step to … Continue reading →

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Genetics Genetic Engineering Engineer Research 40

Advarra

JUNE 13, 2023

Research in gene therapies and genetically engineered drugs and vaccines are growing exponentially, and will only continue to become more popular. This was just one of many questions we explore in our comprehensive survey of research sites and their internal activation practices. between 2020-2027.

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BioTech 365

APRIL 9, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing … Continue (..)

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Scienmag

DECEMBER 28, 2020

Texas A&M AgriLife researchers’ work to aid mosquito control efforts To control mosquito populations and prevent them from transmitting diseases such as malaria, many researchers are pursuing strategies in mosquito genetic engineering.

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Genetic Engineering Genetics Gene Engineer 40

BioTech 365

SEPTEMBER 8, 2020

-Genetically engineered therapy treats relapsed or refractory large B-cell lymphoma, a blood cancer- MILWAUKEE–(BUSINESS WIRE)–The CIBMTR® (Center for International Blood and Marrow Transplant Research®) today announced that it has reached a study enrollment goal 2 years early, and 1,500 patients … Continue reading → (..)

Genetic Engineering 40

Genetic Engineering Engineer Genetics Marketing 40

The Pharma Data

JANUARY 19, 2021

In the paper, researchers from Johns Hopkins University and elsewhere found a natural long-form transactivating CRISPR RNA (tracr-L) in Streptococcus pyogenes that functions to downregulate its endogenous CRISPR-Cas9 system. But altering the tracr-L with genetic engineering to make it function more like a guide RNA increased CRISPR-Cas9 cuts.

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Bacteria Gene Editing Research RNA 52

WCG Clinical

NOVEMBER 17, 2023

Originally released in 1976, the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules ( NIH Guidelines ) serve as the foundation of biosafety-focused oversight of research involving recombinant or synthetic nucleic acids (rsNA). Since then, however, certain genetic engineering technologies (e.g.,

Genome 52

Genome Genomics Gene Editing Genetic Engineering 52

Bioengineer

JULY 19, 2021

The development of KRAS inhibitors is, thus, an extremely active line of research. As they state in the paper to be published in PNAS , “The biological relevance of the expression of two isoforms has puzzled researchers for decades.” ” Lung cancer and metastasis. ” KRAS genes in embryonic development.

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Research Gene Genetic Engineering Genetics 52

Pharmaceutical Technology

MAY 8, 2023

Innovation S-curve for the pharmaceutical industry Zinc-finger nucleases is a key innovation area in pharmaceutical Zinc finger nucleases (ZFNs) are tools used in genetic engineering to cleave a chosen genomic sequence. While Intellia Therapeutics and Jackson ImmunoResearch Laboratories are in second and third positions, respectively.

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Genetics DNA Genetic Engineering Antibody 130

Medical Xpress

FEBRUARY 7, 2023

Patients usually receive FVIII that comes from donor blood or is produced using genetic engineering. Researchers at the Paul-Ehrlich-Institut have found that complement proteins from the immune system strongly influence the reactions of T cells (immune cells) to FVIII and can be involved in inhibitor formation.

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Antibody Genetic Engineering Development Engineer 40