Advarra

JUNE 12, 2023

Gene therapy research is exciting and full of promise, but because of the risks involved, it’s also highly regulated, requiring an institutional biosafety committee (IBC) to provide additional oversight and risk assessment. IRBs are tasked with protecting research subject’s rights and welfare. What Does an IBC Review?

Genetic Engineering 98

Genetic Engineering Gene Therapy Genetics Engineer 98

BioTech 365

AUGUST 24, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Genetically engineered good bacteria could aid in combating disease.Our bodies are home to several bacterial species that help us maintain our health and wellbeing.

Genetic Engineering 40

Genetic Engineering Bacteria Engineer Genetics 40

BioTech 365

DECEMBER 23, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Genetic engineering without unwanted side effects helps fight parasites.Modified CRISPR-Cas9 gene editing scissors are enabling researchers at the University of Zurich to make alterations to the genetic … Continue reading (..)

Genetic Engineering 40

Genetic Engineering Engineer Genetics Gene Editing 40

Scienmag

DECEMBER 3, 2020

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

Genetic Engineering 40

Genetic Engineering Engineer Genetics Bacteria 40

BioPharma Reporter

SEPTEMBER 28, 2021

A new deal sees Bone Therapeutics gain access to iPSC derived, genetically engineered MSCs.

Genetic Engineering 72

Genetic Engineering Engineer Genetics Research 72

BioTech 365

SEPTEMBER 27, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Taking the guesswork out of genetic engineering: STAMPScreen pipeline helps streamline genetic studies in mammalian cell.Today’s genetic engineers have a plethora of resources at their disposal: an … Continue reading (..)

Genetic Engineering 40

Genetic Engineering Genetics Engineer Research 40

Medical Xpress

DECEMBER 5, 2022

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

Protein 74

Protein Genetic Engineering Research Engineer 74

Scienmag

JULY 6, 2022

Researchers have solved a medical mystery in a poorly understood disease by uncovering which cells cause tumours in patients with tuberous sclerosis complex (TSC). As described in Cell Reports, they did this by creating genetically engineered kidney organoids, or “mini-kidneys” grown from human tissue.

Genetic Engineering 73

Genetic Engineering Engineer Genetics Research 73

Scienmag

SEPTEMBER 10, 2021

Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases.

Genetics 59

Genetics Genetic Engineering Engineer Research 59

BioTech 365

APRIL 21, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: International research team argues for combination of organic farming and genetic engineering.For more sustainability on a global level, EU legislation should be changed to allow the use … Continue reading →

Genetic Engineering 40

Genetic Engineering Genetics Engineer Research 40

Scienmag

MARCH 19, 2021

Treatment involving a single injection has long-lasting effects BOSTON – Researchers have used a genetic engineering strategy to dramatically reduce levels of tau–a key protein that accumulates and becomes tangled in the brain during the development of Alzheimer’s disease–in an animal model of the condition.

Genetic Engineering 66

Genetic Engineering Gene Therapy Gene Engineer 66

Scienmag

SEPTEMBER 8, 2020

Credit: Avalos Lab/Princeton University Researchers at Princeton University have created a new and improved way to more precisely control genetically engineered bacteria: by simply switching the lights on and off. Working in E.

Bacteria 56

Bacteria Genetic Engineering Engineer Genetics 56

Scienmag

OCTOBER 14, 2020

Scientists prove cell-cultured meat products can offer enhanced nutrition compared to conventionally produced meat A group of researchers at Tufts University have genetically engineered cow muscle cells to produce plant nutrients not natively found in beef cells.

Engineer 40

Engineer Genetic Engineering Genetics Scientist 40

Scienmag

DECEMBER 21, 2020

Credit: Agricultural Research Service-USDA.

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Genetic Engineering Engineer Genetics Scientist 52

Scienmag

MARCH 5, 2021

Researchers develop tunable system that harnesses the spread of cargo carried by gene drives Credit: Gerard Terradas, UC San Diego Powerful new genetic engineering methods have given scientists the potential to revolutionize several sectors of global urgency.

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Gene Scientist Genetic Engineering Genetics 52

pharmaphorum

NOVEMBER 1, 2021

Delytact (teserpaturev) is a genetically engineered oncolytic herpes simplex virus type 1 (HSV-1) that was approved for marketing in Japan earlier this year, and received pricing approval in August at 1.43 million yen (around $12,500) per dose, according to a Pharma Japan report.

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Genetic Engineering Clinical Trials Clinical Trials Trials 122

Scienmag

APRIL 27, 2021

First-of-its-kind advance holds promise for making new strides in research, treatments Irvine, Calif., April 27, 2021 — University of California, Irvine biologists have developed a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer’s disease.

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Genetic Engineering Genetics Engineer Development 51

Advarra

AUGUST 8, 2023

Gene therapy research is booming in the clinical setting. In this blog, we summarize the growth, risks, and regulatory requirements for gene therapy research. We also discuss how a centralized biosafety review process can benefit this type of research.

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Gene Therapy Gene Research Genetics 52

WCG Clinical

AUGUST 27, 2024

The NIH Guidelines also stipulate that at least two members of each IBC come from the surrounding community and be unaffiliated with the institution where the research is occurring apart from their membership on the IBC. Many of those original concerns of the 1970s and 1980s surrounding genetic engineering have lessened over time.

Genetic Engineering 52

Genetic Engineering Engineer Compliance Genetics 52

pharmaphorum

DECEMBER 24, 2020

The US National Institutes of Health said that the research it had co-funded used AI to transform a bacterial protein into a new research tool. It was led by researchers in the lab of Dr Lin Tian, principal investigator at the University of California Davis School of Medicine.

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Development Drugs Protein Genetic Engineering 77

XTalks

JULY 31, 2020

According to studies conducted by researchers at Cincinnati Children’s Hospital, the bacteria can help heal damaged intestinal tissues. The study developed and researched microbe-controlled and genetically-engineered mice to understand the healing response in the intestine when receiving specific signals from bacteria.

Bacteria 98

Bacteria Genetic Engineering Engineer Research 98

BioTech 365

FEBRUARY 5, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Can a miniscule worm hold the secret to genetically reversing brain damage? A team of Hebrew University researchers have successfully used genetic engineering as a first step to … Continue reading →

Genetics 40

Genetics Genetic Engineering Engineer Research 40

BioTech 365

APRIL 9, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing … Continue (..)

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Gene Expression DNA Gene Editing Gene 40

Scienmag

DECEMBER 28, 2020

Texas A&M AgriLife researchers’ work to aid mosquito control efforts To control mosquito populations and prevent them from transmitting diseases such as malaria, many researchers are pursuing strategies in mosquito genetic engineering.

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Genetic Engineering Genetics Gene Engineer 40

BioTech 365

SEPTEMBER 8, 2020

-Genetically engineered therapy treats relapsed or refractory large B-cell lymphoma, a blood cancer- MILWAUKEE–(BUSINESS WIRE)–The CIBMTR® (Center for International Blood and Marrow Transplant Research®) today announced that it has reached a study enrollment goal 2 years early, and 1,500 patients … Continue reading → (..)

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Genetic Engineering Engineer Genetics Marketing 40

The Pharma Data

JANUARY 19, 2021

In the paper, researchers from Johns Hopkins University and elsewhere found a natural long-form transactivating CRISPR RNA (tracr-L) in Streptococcus pyogenes that functions to downregulate its endogenous CRISPR-Cas9 system. But altering the tracr-L with genetic engineering to make it function more like a guide RNA increased CRISPR-Cas9 cuts.

Bacteria 52

Bacteria Gene Editing Research RNA 52

WCG Clinical

NOVEMBER 17, 2023

Originally released in 1976, the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules ( NIH Guidelines ) serve as the foundation of biosafety-focused oversight of research involving recombinant or synthetic nucleic acids (rsNA). Since then, however, certain genetic engineering technologies (e.g.,

Genome 52

Genome Genomics Gene Editing Genetic Engineering 52

Bioengineer

JULY 19, 2021

The development of KRAS inhibitors is, thus, an extremely active line of research. As they state in the paper to be published in PNAS , “The biological relevance of the expression of two isoforms has puzzled researchers for decades.” ” Lung cancer and metastasis. ” KRAS genes in embryonic development.

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Research Gene Genetic Engineering Genetics 52

Medical Xpress

FEBRUARY 7, 2023

Patients usually receive FVIII that comes from donor blood or is produced using genetic engineering. Researchers at the Paul-Ehrlich-Institut have found that complement proteins from the immune system strongly influence the reactions of T cells (immune cells) to FVIII and can be involved in inhibitor formation.

Antibody 40

Antibody Genetic Engineering Development Engineer 40

pharmaphorum

AUGUST 19, 2020

billion acquisition of Forty Seven by Gilead is an example of the explosive excitement and investment into macrophage-directed therapies, utilizing CD47 checkpoint blockades, repolarization approaches and engineered macrophages, that we have witnessed in recent months.

Genetic Engineering 52

Genetic Engineering Engineer Genetics Antibody 52

FDA Law Blog

DECEMBER 8, 2022

labeling of major food allergens in bulk foods, dietary supplements, protein-free ingredients, and foods produced through genetic engineering); and. labeling of major food allergens in bulk foods, dietary supplements, protein-free ingredients, and foods produced through genetic engineering); and. 1, 2023, sesame.

Genetic Engineering 59

Genetic Engineering Containment Cosmetics Protein 59

XTalks

NOVEMBER 23, 2020

Developed by researchers at the University of Oxford, the COVID vaccine is an adenovirus vector-based vaccine derived from chimpanzees that contains a genetically engineered virus that causes the common cold in chimpanzees, along with the spike protein of the SARS-CoV-2 coronavirus.

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Vaccination Vaccine Clinical Trials Clinical Trials 97

pharmaphorum

MAY 7, 2021

CRISPR’s deal with Nkarta aims to create genetically engineered NK cells, which are harvested and used to create a bank of “off the shelf” cells that can administered to patients like a drug. Nkarta also gets a license to CRISPR gene editing to an unlimited number of its own NK cell therapy products.

Gene Editing 52

Gene Editing Gene Genetic Engineering DNA 52

Roots Analysis

FEBRUARY 15, 2022

Presently, there are several companies and universities, which are exploring the potential of different gene editing technologies beyond CRISPR for basic research, and the development of gene editing solutions. LAGLIDADG homing endonucleases (“meganucleases”) are highly specific DNA cleaving enzymes that are used for genome engineering.

Genome 52

Genome Genomics Gene Editing DNA 52

The Pharma Data

SEPTEMBER 1, 2021

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation. million adults in the United States.

Drugs 52

Drugs Engineer Drug Delivery Gene 52

The Pharma Data

JANUARY 17, 2021

Immuno-oncology is a leading research priority because it uses the body’s own immune system to effectively treat some types of cancer. This can prevent researchers from determining therapeutic efficacy in a preclinical study. Taconic Biosciences is a fully-licensed, global leader in genetically engineered rodent models and services.

Genetic Engineering 40

Genetic Engineering Genetics Engineer Immune Response 40

Bioengineer

JULY 21, 2021

Researchers have proposed a new scoring system for wound healing in mice based on parameters in each phase of healing, as described in an article in the peer-reviewed journal Stem Cells and Development. . publishers is known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research.

Genetic Engineering 52

Genetic Engineering Development Engineer Genetics 52