Pharmaceutical Technology

SEPTEMBER 8, 2024

Interferon alfa-2b is under clinical development by Center for Genetic Engineering and Biotechnology and currently in Phase II for Genital Warts (Condylomata Acuminata).

Genetic Engineering 100

Genetic Engineering Engineer Genetics Clinical Development 100

Pharmaceutical Technology

JUNE 10, 2023

CIGB-128 is under clinical development by Center for Genetic Engineering and Biotechnology and currently in Phase I for Brain Tumor. According to GlobalData, Phase I drugs for Brain Tumor does not have sufficient historical data to build an indication benchmark PTSR for Phase I.

Genetic Engineering 100

Genetic Engineering Engineer Genetics Clinical Trials 100

Pharmaceutical Technology

JUNE 10, 2023

CIGB-128 is under clinical development by Center for Genetic Engineering and Biotechnology and currently in Phase I for Brain Tumor. According to GlobalData, Phase I drugs for Brain Tumor does not have sufficient historical data to build an indication benchmark PTSR for Phase I.

Genetic Engineering 100

Genetic Engineering Engineer Genetics Clinical Trials 100

AuroBlog - Aurous Healthcare Clinical Trials blog

AUGUST 7, 2023

New research from ETH Zürich in Switzerland could see future wearable devices (with perhaps a few implants and a touch of genetic engineering) boost our health directly. Fitness trackers help you stay healthy by keeping count of your steps and monitoring your heart rate, driving you on to hit those cardio goals.

Genetic Engineering 246

Genetic Engineering Gene Engineer Genetics 246

Pharmaceutical Technology

APRIL 6, 2023

Ginkgo Bioworks has strengthened its end-to-end R&D capabilities in gene therapy with the purchase of adeno-associated virus (AAV) capsid discovery and engineering assets from StrideBio, for an undisclosed sum. As part of the transaction, one StrideBio employee will be transferred to Ginkgo’s mammalian engineering team.

Engineer 130

Engineer Gene Therapy Gene Manufacturing 130

BioSpace

JULY 27, 2021

breakthrough study has found that altering the genetic makeup of malaria-carrying mosquito species could be the key to stopping the spread of the malaria virus and finally eradicating the disease.

Genetic Engineering 95

Genetic Engineering Genetics Engineer 95

Scienmag

OCTOBER 16, 2020

International research team including University of Göttingen explains advantages of molecular breeding methods Credit: M Qaim More than two billion people worldwide suffer from micronutrient malnutrition due to deficiencies in minerals and vitamins.

Genetic Engineering 98

Genetic Engineering Engineer Genetics Development 98

Pharmaceutical Technology

MAY 17, 2023

The deal will see the integration of Scribe’s new CRISPR by Design approach and Prevail’s expertise in developing genetic medicines for neurological disorders for specific genetic targets. Under the deal, Prevail obtains exclusive rights to use Scribe’s CRISPR X-Editing (XE) technologies to develop the medicines.

Genetics 130

Genetics Medicine In-Vivo Gene Therapy 130

STAT News

MARCH 14, 2023

Saying genetics researchers inconsistently and inappropriately use racial and ethnic labels that fail to capture the complex patterns of human genetic variation, the National Academies of Sciences, Engineering, and Medicine issued a report Tuesday calling for a transformation in how such descriptors are used.

Genetics 98

Genetics Research Genome Genomics 98

Scienmag

SEPTEMBER 18, 2020

Two active genetics strategies help address concerns about gene-drive releases into the wild Credit: Ana Silva In the past decade, researchers have engineered an array of new tools that control the balance of genetic inheritance.

Genetics 86

Genetics Gene Engineer Research 86

BioSpace

JULY 11, 2022

Epic Bio aims to transform genetic medicine by developing a new class of drugs that target the epigenome to alter gene expression.

Genetics 81

Genetics Gene Expression Medicine Engineer 81

BioSpace

DECEMBER 4, 2020

Has China discovered a super-soldier formula through the capabilities of genetic engineering? government official claims this is exactly what is happening.

Genetic Engineering 145

Genetic Engineering Engineer Genetics 145

Pharmaceutical Technology

SEPTEMBER 23, 2024

Learn how their innovative method enhances genetic engineering and biotechnology. Discover Telesis Bio Inc.'s s groundbreaking patent for synthesizing specific DNA sequences.

DNA 130

DNA Genetic Engineering Engineer Genetics 130

Scienmag

APRIL 27, 2022

Researchers at University of California San Diego School of Medicine and Jacobs School of Engineering, with colleagues at Baylor College of Medicine, have used a systems biology approach to parse the genetic diversity of Clostridioides difficile, a particularly problematic pathogen in health care settings.

Genetics 85

Genetics Engineer Medicine Research 85

Pharmaceutical Technology

MAY 10, 2023

SYNB1934 consumes Phe in the gastrointestinal (GI) tract by leveraging genetic engineering of the drug or drug-carrying capsule, probiotic escherichia coli (E coli) Nissle. The orally administered, non-systemically absorbed drug candidate SYNB1934 has been designed for reducing blood phenylalanine (Phe) levels in PKU patients.

Genetic Engineering 261

Genetic Engineering Drugs Engineer Genetics 261

Pharmaceutical Technology

JUNE 10, 2024

Explore the groundbreaking genetic modifications enhancing antibody engineering. Discover how AbCellera Biologics Inc's patented transgenic mouse with a unique LDH expression cassette revolutionizes immunoglobulin library production, enabling extended HCDR3 regions.

Production 130

Production Engineer Genetics Antibody 130

Scienmag

JULY 1, 2022

Curing debilitating genetic diseases is one of the great challenges of modern medicine. During the past decade, development of CRISPR technologies and advancements in genetics research brought new hope for patients and their families, although the safety of these new methods is still of significant concern.

Genetics 97

Genetics Genetic Disease Medicine Development 97

Medical Xpress

MARCH 8, 2023

Combining discoveries in cancer immunology with sophisticated genetic engineering, Columbia University researchers have created a sort of "bacterial suicide squad" that targets tumors, attracting the host's own immune cells to the cancer to destroy it.

Bacteria 75

Bacteria Engineer Genetic Engineering Genetics 75

Pharmaceutical Technology

SEPTEMBER 5, 2022

Administered as a single dose, the genetically engineered vaccine has the replication-defective adenovirus type 5 vector that expresses the spike S protein of the SARS-CoV-2 virus. In May, CanSinoBIO received an emergency use listing (EUL) from the World Health Organization (WHO) for its recombinant Covid-19 shot, Convidecia.

Vaccination 264

Vaccination Vaccine Genetic Engineering Clinical Trials 264

Pharmaceutical Technology

APRIL 11, 2023

The finding was made as part of a study published in the journal Nature Biomedical Engineering. Kelley added: “Engineering-based tools allow you to do things that open up new areas of biology. The study focuses on the isolation of tumour-reactive lymphocytes from peripheral blood via microfluidic immunomagnetic cell sorting.

Scientist 244

Scientist Engineer Clinical Trials Clinical Trials 244

Pharmaceutical Technology

JUNE 24, 2022

The protein-based vaccine is engineered from the genetic sequence of the SARS-CoV-2 virus’ initial strain. Novavax has obtained emergency use authorization (EUA) for its Covid-19 vaccine, Nuvaxovid (NVX-CoV2373), from the Taiwan Food and Drug Administration for use in people of the age 18 years and above.

Vaccination 263

Vaccination Vaccine Clinical Trials Clinical Trials 263

Advarra

MARCH 31, 2023

The use of engineered genetic materials in clinical trials is rapidly expanding, with potential applications for genetic vaccines, gene-modified cellular therapies, and gene therapies. A key part of the IBC’s evaluation is assessing the risks posed by the engineered genetic materials.

Engineer 52

Engineer Genetics Clinical Research Research 52

Scienmag

AUGUST 11, 2020

Assessing clinical data across the lifespan identified the impact of genetic epilepsies on affected children’s lives Philadelphia, August 11, 2020 – A team of researchers at Children’s Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) further bridged the gap between genomic information (..)

Genetics 70

Genetics Genome Genomics Engineer 70

Pharmaceutical Technology

JANUARY 5, 2023

Under the multi-year strategic partnership, Prevail will detect and advance capsids, which are clinically translatable, along with its cargo to develop the transformative genetic medicines by using Capsida’s novel adeno-associated virus (AAV) engineering platform.

Gene Therapy 237

Gene Therapy Gene Development Engineer 237

Advarra

JUNE 13, 2024

Recombinant DNA technologies and genetically modified biological agents are being adapted for a wide scope of therapeutic applications, and their use is becoming increasingly common in clinical trials. How can I protect myself from exposure? What should I do if I’m exposed?

Genetic Engineering 52

Genetic Engineering Clinical Trials Clinical Trials Engineer 52

BioSpace

AUGUST 31, 2020

Boston Pharmaceuticals licensed the drug candidate BOS-580, an injectable, genetically engineered variant of human FGF21.

Licensing 111

Licensing Licensing Genetic Engineering Engineer 111

STAT News

MARCH 1, 2023

Genome editing summits are generally friendly, nerdy affairs, but for a moment at a Lisbon hotel last June, the conversation at the FASEB genome engineering conference grew tense. ” It was a rare moment: Tessera had raised around $600 million and passed a $1 billion valuation, but published little in academic medical journals.

Gene Editing 119

Gene Editing Genome Genomics Genetic Disease 119

Pharmaceutical Technology

APRIL 26, 2023

This marks the first-ever designation for genetically modified gamma-delta T cell therapies. INB-400, an autologous, genetically engineered gamma-delta T cell therapy, is the company’s DeltEx chemotherapy-resistant autologous and allogeneic drug-resistant immunotherapy (DRI) technology.

Genetic Engineering 130

Genetic Engineering Drugs Genetics Engineer 130

Scienmag

SEPTEMBER 10, 2021

Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases.

Genetics 59

Genetics Genetic Engineering Engineer Research 59

Medical Xpress

JANUARY 5, 2023

A new study by Burke Neurological Institute (BNI), Weill Cornell Medicine, finds that activation of MAP2K signaling by genetic engineering or non-invasive repetitive transcranial magnetic stimulation (rTMS) promotes corticospinal tract (CST) axon sprouting and functional regeneration after spinal cord injury (SCI) in mice.

Genetic Engineering 117

Genetic Engineering Engineer Genetics Medicine 117

Pharmaceutical Technology

MARCH 11, 2024

is revolutionizing adoptive cell transfer therapies with patented methods to reduce HLA-A protein expression in engineered human cells. Discover how Intellia Therapeutics Inc. Explore the potential for treating cancer, infectious diseases, and autoimmune disorders.

Protein 100

Protein Genetics Engineer 100

Medical Xpress

NOVEMBER 10, 2022

In recent years, genetically re-engineered immune cells—armed with molecular weaponry to recognize and destroy tumor cells—have changed the landscape of cancer treatment.

Engineer 123

Engineer Genetics Development Research 123

Scienmag

MARCH 30, 2022

Mineral systems: Their advantages in terms of developing holistic genetic models and for target generation in global mineral exploration Credit: GeoGeo Mineral systems: Their advantages in terms of developing holistic genetic models and for target generation in global mineral exploration [link] Announcing a new publication for Geosystems and Geoenvironment (..)

Genetics 89

Genetics Development Engineer 89

BioSpace

APRIL 25, 2024

The genetic engineering startup, recently honored by BioSpace readers for its work environment, is downsizing as it seeks to launch its first clinical trials.

Genetic Engineering 92

Genetic Engineering Engineer Clinical Trials Clinical Trials 92

STAT News

JULY 11, 2022

Then it was almost instantly derailed by the death of an 18-year-old clinical trial volunteer named Jesse Gelsinger after he received a genetically engineered virus that had been developed to treat his rare liver condition. Twenty-three years ago, the field of gene therapy was bursting with the promise of breakthrough treatments.

Gene 111

Gene Gene Therapy Genetic Engineering Engineer 111

Pharmaceutical Technology

FEBRUARY 13, 2023

Gene therapies are an attractive way of targeting the underlying genetic mutations, but traditional approaches cannot be used while targeting mutations for Dravet Syndrome, forcing researchers to develop new ways. Meanwhile, others are researching the link between gene variation and different responses to treatments.

Research 264

Research Gene Gene Therapy Genomics 264

Scienmag

JUNE 27, 2021

Credit: McMaster University HAMILTON, ON June 28, 2021 — Researchers at McMaster University have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors.

Engineer 61

Engineer Genetic Engineering Research Genetics 61