BioSpace

MARCH 10, 2021

Intellia Therapeutics presented preclinical data of its non-viral genome editing platform at the Keystone eSymposium: Precision Engineering of the Genome, Epigenome and Transcriptome.

In-Vivo 94

In-Vivo Genome Genomics Engineer 94

BioTech 365

AUGUST 17, 2021

ERS Genomics and Cellular Engineering Technologies Enter CRISPR/Cas9 License Agreement ERS Genomics and Cellular Engineering Technologies Enter CRISPR/Cas9 License Agreement License allows Cellular Engineering Technologies to develop, manufacture and commercialize next generation stem cell lines using CRISPR/Cas9 technology DUBLIN & … Continue (..)

Engineer 40

Engineer Genome Genomics Licensing 40

BioTech 365

AUGUST 18, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: ERS Genomics and Cellular Engineering Technologies collaborating. from European Biotechnology – first and foremost in European biotech [link].

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Engineer Genome Genomics Research 40

Roots Analysis

FEBRUARY 15, 2022

Gene engineering based on recombination was pioneered in the mid-1990s; Currently, development of gene editing technologies has opened up the possibility of modifying genomic sequences in both eukaryotic and prokaryotic organisms. Genome Editing is a way of making changes in the DNA. Type of Genome Editing: Zinc-Finger Nuclease.

Genomics 52

Genomics Genome Gene Editing DNA 52

BioTech 365

AUGUST 11, 2021

ATUM Announces Issuance of US Patents Covering Novel Enzymes Critical to Genome Engineering Applications ATUM Announces Issuance of US Patents Covering Novel Enzymes Critical to Genome Engineering Applications New patents cover three novel transposons that enable the efficient and broad … Continue reading →

Engineer 40

Engineer Genome Genomics 40

BioTech 365

SEPTEMBER 6, 2021

Global Genome Editing Market Segment Forecasts 2021-2028: Cell Line Engineering Dominates the Market – ResearchAndMarkets.com Global Genome Editing Market Segment Forecasts 2021-2028: Cell Line Engineering Dominates the Market – ResearchAndMarkets.com DUBLIN–(BUSINESS WIRE)–The “Global Genome Editing Market Size, Share (..)

Genome 40

Genome Genomics Engineer Marketing 40

Pharmaceutical Technology

FEBRUARY 13, 2023

About 30% of epilepsy patients do not respond to available anti-seizure treatments, says Dr. Dario Englot, director of functional neurosurgery at Vanderbilt University’s Institute for Surgery and Engineering in Nashville, Tennessee. In his work, Ferraro focuses on the links between gene variations and different responses to drugs.

Research 264

Research Gene Gene Therapy Genome 264

pharmaphorum

JANUARY 29, 2021

Genome editing is an exciting but still nascent field, and companies in the area face as many obstacles as they do opportunities. ZFPs can be engineered to make zinc finger nucleases, or ZFNs, which are proteins that can be used to edit genomes by knocking select genes in or out to specifically modify DNA sequences.

Gene Editing 145

Gene Editing Gene Gene Therapy In-Vivo 145

BioTech 365

SEPTEMBER 3, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers develop an engineered ‘mini’ CRISPR genome editing system.The common analogy for CRISPR gene editing is that it works like molecular scissors, cutting out select sections of … Continue reading → (..)

Engineer 40

Engineer Genome Genomics Gene Editing 40

Pharmaceutical Technology

SEPTEMBER 29, 2022

The alliance will leverage the CRISPR genome editing technologies of Scribe to facilitate in genetic modification of new natural killer (NK) cell therapeutics for cancer. According to the deal, Sanofi will make an upfront payment of $25m to Scribe.

Development 130

Development In-Vivo Genome Genomics 130

Scienmag

MARCH 31, 2021

Company accelerates commercialization efforts to address a million at-risk patients’ unmet needs Bluestar Genomics announces today it received U.S. Food and Drug Administration (FDA) Breakthrough Device designation for its proprietary noninvasive pancreatic cancer detection test in patients with new-onset diabetes.

Genome 75

Genome Genomics Development Drugs 75

BioTech 365

OCTOBER 27, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: ElevateBio cuts a deal for Life Edit, adding genome engineering tech to support gene therapy pipeline.ElevateBio cuts a deal for Life Edit, adding genome engineering tech to … Continue reading →

Gene Therapy 40

Gene Therapy Engineer Genome Genomics 40

Pharmaceutical Technology

JUNE 5, 2023

Social engineering attacks will rise, in addition to phishing, smishing and deepfake attacks. There is also a debate as to how genomic information should be protected,” he adds. Genomic data plays a central role in the future of the field, especially as new cell therapies and more personalised medicine comes of age.

Genome 276

Genome Genomics Regulation Compliance 276

BioTech 365

AUGUST 20, 2021

Editas Medicine Presents Data on New SLEEK Gene Editing Technology at Cold Spring Harbor Laboratory’s Genome Engineering: CRISPR Frontiers Meeting Editas Medicine Presents Data on New SLEEK Gene Editing Technology at Cold Spring Harbor Laboratory’s Genome Engineering: CRISPR Frontiers Meeting … Continue reading →

Gene Editing 40

Gene Editing Genome Genomics Engineer 40

BioTech 365

JANUARY 22, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researcher expands plant genome editing with newly engineered variant of CRISPR-Cas9.Alongside

Engineer 40

Engineer Genome Genomics Research 40

pharmaphorum

MARCH 24, 2022

LifeMine has developed an industrialised, genomics-based discovery engine that it hopes will take a broad, systematic approach to identifying new compounds from fungi and screening them for activity against disease targets. Image by jggrz from Pixabay .

Medicine 105

Medicine Genomics Genome Engineer 105

STAT News

MARCH 16, 2023

Before there was CRISPR, aspiring genome editors relied on an island of misfit, less elegantly named enzymes: Zinc-finger nucleases, TALENs, recombinases. They were stubborn, inflexible enzymes, requiring endless engineering. They were stubborn, inflexible enzymes, requiring endless engineering.

Gene Editing 98

Gene Editing Gene DNA Genomics 98

Scienmag

FEBRUARY 25, 2021

Publication in Science Credit: David Porubsky, University of Washington In 2001, the International Human Genome Sequencing Consortium announced the first draft of the human genome reference sequence. This reference, however, […].

Genome 60

Genome Genomics Genome Project Genetics 60

Scienmag

FEBRUARY 14, 2022

This “lossiness” largely preserves the image while vastly reducing its file size — and serves as the inspiration for a new research direction in genomics, according to Justin Pritchard, assistant professor of biomedical engineering. […].

Research 88

Research Gene Genome Genomics 88

Pharmaceutical Technology

MARCH 8, 2023

The new technologies will also overcome the manufacturing bottlenecks in delivering advanced engineered cell products. Its focus areas include human systems, precision diagnostics, data sciences, next-generation biomanufacturing, and genomic medicines. The University of Pennsylvania Immunotherapy Richard W.

Gene Therapy 244

Gene Therapy Manufacturing Gene Production 244

STAT News

MARCH 14, 2023

Saying genetics researchers inconsistently and inappropriately use racial and ethnic labels that fail to capture the complex patterns of human genetic variation, the National Academies of Sciences, Engineering, and Medicine issued a report Tuesday calling for a transformation in how such descriptors are used. Read the rest…

Genetics 98

Genetics Research Genomics Genome 98

The Pharma Data

JANUARY 31, 2021

(NASDAQ: ILMN), the global leader in DNA sequencing and array-based technologies, and Sequoia Capital China , a leading investment firm, today announced a collaboration to catalyze the startup ecosystem in China with the launch of the Sequoia Capital China Intelligent Healthcare Genomics Incubator, Powered by Illumina.

Genomics 52

Genomics Genome Life Science DNA 52

Pharmaceutical Technology

JUNE 4, 2023

AAV genomes are highly compact, with overlapping coding regions, alternate splicing schemes, and multiple transcription initiation codons. There are two main genes in the AAV genome, rep and cap, which encode nine different proteins.

Gene 262

Gene Gene Therapy Genetics DNA 262

Pharmaceutical Technology

JUNE 23, 2022

Coronaviruses, like Covid-19, are a notorious group of infectious agents that include a large class of viruses with RNA genomes, similar to the human DNA genome, that depend on well-organised protein structures crucial for viral growth and replication.

Drugs 130

Drugs Protein Genome Genomics 130

XTalks

AUGUST 29, 2022

CRISPR is notable for engineering living cells, allowing scientists to edit, turn off, delete, or replace genes in a cell’s genome. It is difficult to control where the viral vectors insert genes in the genome, and it is difficult to manufacture large quantities of clinical-grade viral vectors.

Gene Editing 98

Gene Editing DNA Gene Genome 98

Scienmag

SEPTEMBER 29, 2020

Credit: Dr Ira Deveson A new mobile app has made it possible to analyse the genome of the SARS-CoV-2 virus on a smartphone in less than half an hour.

Genome 55

Genome Genomics Genetics Scientist 55

Pharmaceutical Technology

FEBRUARY 15, 2023

Innovation S-curve for the pharmaceutical industry Gene splicing using nucleases is a key innovation area in the pharmaceutical industry Nucleases play a fundamental role in the field of recombinant DNA technology, or genetic engineering. Nucleases are enzymes that hydrolytically cleave the phosphodiester backbone of DNA.

Gene Splicing 130

Gene Splicing Gene DNA Recombinant DNA Technology 130

BioTech 365

JULY 26, 2021

ERS Genomics and Japan SLC Sign CRISPR/Cas9 License Agreement ERS Genomics and Japan SLC Sign CRISPR/Cas9 License Agreement Nobel prize winning CRISPR technology to be applied in development of genetically engineered animal models DUBLIN & SHIZUOKA, Japan–(BUSINESS WIRE)–ERS Genomics Limited, … Continue reading →

Genome 40

Genome Genomics Licensing Licensing 40

BioTech 365

MARCH 9, 2021

ERS Genomics and Setsuro Tech Sign CRISPR/Cas9 License Agreement ERS Genomics and Setsuro Tech Sign CRISPR/Cas9 License Agreement Nobel prize winning CRISPR technology to be applied in development of genetically engineered cell and animal models DUBLIN & TOKUSHIMA, Japan–(BUSINESS WIRE)–ERS … Continue reading →

Genomics 40

Genomics Genome Licensing Licensing 40

BioTech 365

MARCH 29, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Study reports six novel variants for CRISPR-Cas12a in plants, expanding genome engineering.In

Genome 40

Genome Genomics Engineer Research 40

Pharmaceutical Technology

MAY 17, 2023

The platform based on Scribe CRISPR by Design applies holistic engineering to convert bacterial immune systems into key genome editing technologies targeting the patients’ specific requirements. “Our goal now is to more broadly enable therapies to help people living with these conditions.”

Genetics 130

Genetics Medicine In-Vivo Gene Therapy 130

BioPharma Reporter

AUGUST 29, 2023

Synthego, a leading provider of industrialized genome editing solutions, and bit.bio, the company coding human cells for novel cures, have expanded their partnership to build a platform centered on the implementation of synthetic circuitry in cells for therapeutic application.

Engineer 52

Engineer Genome Genomics Development 52

Pharmaceutical Technology

FEBRUARY 23, 2023

Moderna Genomics general manager and chief scientific officer Eric Huang said: “Through our collaboration with Life Edit, we hope to harness the power of gene editing technologies as part of our broader research and development engine, helping to advance our mission and deliver on the promise of mRNA.”

Gene Editing 147

Gene Editing Gene In-Vivo Gene Therapy 147

Pharmaceutical Technology

JULY 22, 2022

TX200 is a collection of autologous regulatory T cells (Tregs) that are engineered to express an HLA-A2 Chimeric Antigen Receptor (CAR) to prevent immune-mediated rejection in HLA-A2 mismatched kidney transplants from a living donor.

Medicine 130

Medicine Production Genome Genomics 130

BioTech 365

SEPTEMBER 21, 2020

In a leap forward for immune privileged cell and organ therapy, researchers create first clinical xenotransplantation prototype with enhanced human immune compatibility and without active porcine endogenous retrovirus (PERV) Results published in Nature Biomedical Engineering demonstrate potential of Qihan’s genome … Continue reading → (..)

Engineer 40

Engineer Genome Genomics Research 40

Scienmag

APRIL 26, 2021

. — In October of 2020, Jennifer Doudna and Emmanuelle Charpentier were awarded the Nobel Prize in chemistry for their discovery of an adaptable, easy way to edit genomes, known as CRISPR, which has transformed the world of genetic engineering.

Genome 40

Genome Genomics Genetic Engineering Genetics 40

Scienmag

JANUARY 13, 2021

To discover these associations, researchers need to compare the genomes of many individuals at millions of genetic locations or markers, and therefore require cost-effective genotyping technologies. A new statistical method, developed […].

Genome 57

Genome Genomics Genotype Genetics 57