Outsourcing Pharma

SEPTEMBER 10, 2021

A leader from ACG Engineering shares insight on how âsmartâ drug manufacturing, accelerated by COVID-19, can best be put to work now and in months to come.

Manufacturing 105

Manufacturing Engineer Drugs Contract Manufacturing 105

Pharmaceutical Technology

AUGUST 25, 2022

Sonoma Biotherapeutics has signed a lease agreement for setting up an 83,000ft² research and development (R&D) and manufacturing centre for cell therapies. A cGMP-compliant production facility will be housed at the centre for manufacturing cell products at scale. The RMR Group is redeveloping the property into Unison Elliott Bay.

Manufacturing 130

Manufacturing Engineer Gene Therapy Production 130

pharmaphorum

JANUARY 6, 2021

Louis van de Wiel, Vice President, Site Head EU Manufacturing, Kite, a Gilead Company, reveals the complexity that sits behind the process of individualised cell therapy – and why team culture makes it work. This thought leadership series has been paid and developed by Kite, a Gilead Company. The journey of the cell.

Manufacturing 119

Manufacturing Production Engineer Genetics 119

Pharmaceutical Technology

JANUARY 20, 2023

However, scaling processes up to a manufacturing scale is far from straightforward. The challenges with scaling up mAbs therapy production When developing a mAb therapeutic, there has traditionally been inconsistency between early lab processes, pilot processes and commercial manufacturing.

Manufacturing 130

Manufacturing Production Development Engineer 130

BioPharma Reporter

MARCH 28, 2022

CytoImmune Therapeutics, a clinical-stage immunotherapy company developing a novel class of engineered natural killer (NK) cell-based cancer therapies, has announced the opening of its clinical cell manufacturing facility in Toa Baja, Puerto Rico.

Manufacturing 98

Manufacturing Engineer Development 98

XTalks

JANUARY 30, 2025

Best practices include the use of contained engineering solutions to safeguard drug product integrity and protect operators. This versatility eliminates the need to manufacture separate stock-keeping units (SKUs) for each dosage variation, streamlining inventory management and reducing production costs for pharmaceutical companies.

Manufacturing 52

Manufacturing Development Compliance Production 52

Scienmag

JUNE 17, 2021

Credit: Victoria Chen/Alwin Daus/Pop Lab Ultrathin, flexible computer circuits have been an engineering goal for years, but technical hurdles have prevented the degree of miniaturization necessary to achieve high performance.

Manufacturing 90

Manufacturing Engineer Research 90

pharmaphorum

APRIL 26, 2022

French drugmaker wants the efficiency of its manufacturing operations to go up a gear, and has joined forces with Formula One racing team McLaren to make it happen. The post Sanofi revs up manufacturing with help from McLaren appeared first on.

Manufacturing 97

Manufacturing Pharma Companies Engineer Production 97

Pharmaceutical Technology

JULY 25, 2022

According to Tom Lenaerts, Head of Global Process Engineering at Datwyler, this transformation will reshape the entire healthcare ecosystem. Along the way, the company hopes to find new possibilities to transform its manufacturing processes and improve product quality. Disruptive technologies.

Engineer 286

Engineer Packaging Packaging Production 286

Pharmaceutical Technology

FEBRUARY 3, 2023

Additionally, OSD manufacturing approaches are well developed, with processes that ensure a repeatable distribution of ingredients, uniformity in dissolution, and bioavailability, which verify that the drug product is safe and effective. Compared to other dosage forms, tablets are simpler to manufacture, package, and transport.

Contamination 130

Contamination Manufacturing Containment Production 130

Bio Pharma Dive

NOVEMBER 6, 2023

Industry-leading cold storage manufacturers are engineering new solutions that can reliably meet performance benchmarks while consuming far less energy than yesterday’s ULT and laboratory-grade freezers.

Engineer 144

Engineer Manufacturing 144

Pharmaceutical Technology

JULY 25, 2022

With decreasing margins on the horizon, pharma manufacturers have long shown an interest in specialty generics, which is only expected to rise in the future. Despite this, specialty generics are expected to be the domain of a handful of companies with the necessary manufacturing capabilities and legal backing needed for entering the market.

Drugs 298

Drugs Manufacturing Production Marketing 298

Pharmaceutical Technology

NOVEMBER 22, 2022

The iPSC-based allogeneic cell therapy platform of Umoja leverages its synthetic receptor enabled differentiation (ShRED) manufacturing process to guide iCIL differentiation and development with robust anti-tumour activity. In the initial stage, the partnership will focus on acute myeloid leukaemia (AML) to boost accessibility to patients.

Development 276

Development In-Vivo Engineer Clinical Trials 276

Pharmaceutical Technology

MARCH 8, 2023

Global science and technology innovator Danaher has entered a strategic collaboration with the University of Pennsylvania for cellular immunotherapies to address manufacturing challenges impacting cell therapy uptake. The new technologies will also overcome the manufacturing bottlenecks in delivering advanced engineered cell products.

Gene Therapy 244

Gene Therapy Manufacturing Gene Production 244

XTalks

JANUARY 7, 2025

Symvess is a one-time, single-use, acellular tissue-engineered vessel (ATEV) composed of human extracellular matrix proteins. Manufactured using vascular smooth muscle cells derived from human aortic tissue, Symvess offers a novel solution for patients with traumatic vascular injuries.

FDA Approval 105

FDA Approval Engineer Clinical Trials Clinical Trials 105

XTalks

JUNE 12, 2023

Bristol Myers Squibb (BMS), a multinational pharmaceutical company based in New York City, has announced that its new state-of-the-art cell therapy manufacturing facility in Devens, Massachusetts, has received approval for commercial production from the US Food and Drug Administration (FDA).

Manufacturing 95

Manufacturing Gene Therapy FDA Approval Gene 95

Pharmaceutical Technology

SEPTEMBER 5, 2022

The company has presently attained steady manufacturing of several innovative vaccines and set up a supply chain worldwide to increase accessibility to quality vaccine products for people globally.

Vaccine 264

Vaccine Vaccination Genetic Engineering Clinical Trials 264

Pharmaceutical Technology

JUNE 24, 2022

The protein-based vaccine is engineered from the genetic sequence of the SARS-CoV-2 virus’ initial strain. The totality of preclinical, manufacturing and clinical trial findings that were submitted for analysis formed the basis for the EUA.

Vaccine 263

Vaccine Vaccination Clinical Trials Clinical Trials 263

Pharmaceutical Technology

APRIL 26, 2023

The conceptualisation, development and manufacturing of primary packaging in the pharmaceutical industry require a meticulous and multi-disciplinary approach to ensure that the products meet the highest standards of safety and efficacy.

Packaging 130

Packaging Packaging Manufacturing Development 130

Pharmaceutical Technology

JUNE 29, 2022

For hundreds of years, we have found myriad uses for microbial enzymes in manufacturing – from food, drink, and household products to a range of industrial applications. The enzymes must be manufactured under cGMP conditions – completely free of animal-derived ingredients.”. Developing best-in-class speciality enzymes.

Drugs 295

Drugs Gene Therapy Production Manufacturing 295

Pharmaceutical Technology

JANUARY 6, 2023

It requires having access to proper techniques and skill sets, state-of-the-art equipment, process scientists and engineers who have a deep understanding of Quality by Design (QbD) principles, and methods for product and process characterisation. Expertise in analytical testing, validation, and quality control are also essential.

Production 130

Production Manufacturing Development Bioequivalency 130

XTalks

APRIL 10, 2025

This years honorees tackle the sectors biggest challenges: cutting waste, boosting nutrition and engineering better flavor without compromise. Its platform delivers ingredient solutions for both chefs and food manufacturers, all while diverting tons of waste.

Protein 93

Protein Packaging Packaging Branding 93

Pharmaceutical Technology

DECEMBER 8, 2022

Under the prior deal, Daiichi Sankyo acquired exclusive rights for the development, manufacturing and commercialisation of Yescarta in Japan. Regulators in Japan have granted approval for the manufacturing plant of Kite in El Segundo, California, US, to produce Yescarta for the Japanese market.

Licensing 305

Licensing Licensing Gene Therapy Gene 305

Pharmaceutical Technology

DECEMBER 19, 2022

As per the initial agreement, Sanofi is in charge of these products’ development, manufacturing and marketing while Innate Pharma is entitled to get up to $423.3m (€400m) in development and commercial milestone payments.

Development 264

Development Engineer Clinical Trials Clinical Trials 264

Pharma Mirror

OCTOBER 29, 2021

Telstar will be actively participating at CPhI, to be held in Milan, during 9-11th November 2021, promoting its personalized GMP consultancy & engineering reply to the new trends in pharma. The post Telstar promotes 360º solutions at CPhI Worldwide-2021 appeared first on Pharma Mirror Magazine.

Engineer 130

Engineer Compliance Manufacturing Production 130

Pharmaceutical Technology

MAY 25, 2023

The technology platforms include the Life Edit gene editing platform, an RNA, cell, protein, vector engineering and induced pluripotent stem cells (iPSCs) platform. ElevateBio intends to use the funds to advance its genetic medicine current good manufacturing practice (cGMP) and process development business, BaseCamp.

Gene Therapy 243

Gene Therapy Gene Gene Editing Development 243

Scienmag

APRIL 15, 2022

CAMBRIDGE, MA — Perovskites are a family of materials that are currently the leading contender to potentially replace today’s silicon-based solar photovoltaics.

Engineer 68

Engineer Manufacturing 68

Pharmaceutical Technology

OCTOBER 13, 2022

Inceptor Bio has partnered with cell engineering technology company Avectas to improve CAR-T cell therapies’ development and manufacturing to treat solid tumours. Under the collaboration deal, Inceptor Bio will use the Solupore technology from Avectas instead of electroporation for engineering T cells to yield a healthier T cell.

Development 147

Development Engineer Gene Therapy Gene 147

Pharma Mirror

JUNE 11, 2024

By Michael von Papen, Chief Expert at Pharmatec GmbH – a Syntegon Company When a leading global collagenase manufacturer wants to renew and optimize a system at the heart of its production, technical expertise, and engineering competence is paramount. Moreover, cooperation within the project team needs to be well organized.

Engineer 130

Engineer Manufacturing Production 130

XTalks

JANUARY 21, 2025

From non-invasive cancer diagnostics to life-saving cardiovascular implants, the latest medical devices cleared or approved by the FDA in 2024 reflect the remarkable strides in science and engineering. TriClip G4 System Manufacturer/developer : Abbott Medical Date of FDA approval : April 1, 2024 Approved for : Tricuspid regurgitation (TR).

FDA Approval 105

FDA Approval Manufacturing Development RNA 105

Scienmag

FEBRUARY 26, 2022

A research team in Korea has synthesized metal nanoparticles that can drastically improve the performance of hydrogen fuel cell catalysts by using the semiconductor manufacturing technology.

Manufacturing 84

Manufacturing Research Engineer 84

Scienmag

MAY 23, 2022

Borrowing a technique from inkjet printers, researchers at Princeton Engineering have rolled out a pixel-by-pixel method to program and manufacture soft structures for use in robotics, biomedical devices or architectural features.

Engineer 88

Engineer Manufacturing Research 88

Pharmaceutical Technology

JUNE 12, 2023

Quell Therapeutics and AstraZeneca have entered a collaboration, exclusive option and licence deal for the development, manufacturing and commercialisation of engineered T-regulator (Treg) cell therapies for autoimmune diseases. AstraZeneca will make an upfront payment to Quell of $85m, mostly in cash.

Engineer 130

Engineer Gene Therapy Clinical Trials Clinical Trials 130

Scienmag

NOVEMBER 12, 2020

Credit: Pavel Odinev / Skoltech Scientists from the Skoltech Center for Design, Manufacturing, and Materials (CDMM) have developed a method for designing and manufacturing complex-shaped ceramic bone implants with a controllable porous structure, which largely enhances tissue fusion efficiency.

Scientist 81

Scientist Manufacturing Development Research 81

Pharmaceutical Technology

OCTOBER 6, 2022

But despite this surge in demand, research from GlobalData shows that many CMOs have decreased in-house, non-containment, small molecule manufacturing. These turnkey solutions cover every process through the drug manufacturing life cycle. Finding the right solution. Their active properties must remain intact.

Engineer 130

Engineer Containment Production Manufacturing 130

Pharma Mirror

SEPTEMBER 9, 2021

Sterling Pharma Solutions, a global contract development and manufacturing organisation, today announced the completion of the initial phase of investment at its site in Dudley, UK to create the company’s centre of excellence for research into commercial applications of continuous flow chemistry.

Engineer 130

Engineer Manufacturing Research Development 130

STAT News

OCTOBER 4, 2022

Now two separate research teams have identified a possible culprit in the mix of engineered immune cells created as part of CAR-T therapy.

Scientist 116

Scientist Engineer Pharma Companies Manufacturing 116