Pharmaceutical Technology

APRIL 27, 2023

Bristol Myers Squibb will take over a former Novartis plant to boost viral vector production for chimeric antigen receptor (CAR) T-cell therapies. Bristol Myers Squibb stated that the facility will provide viral vector production capabilities for its two CAR T-cell therapies. This process is both operationally and technically complex.

Production 130

Production Gene Therapy Manufacturing Engineer 130

Pharmaceutical Technology

JULY 22, 2022

Sangamo Therapeutics has received orphan medicinal product designation (OMPD) from the European Commission (EC) for its Investigational autologous Chimeric Antigen Receptor Regulatory T Cell (CAR-Treg) cell therapy, TX200, for solid organ transplantation.

Medicine 130

Medicine Production Genome Genomics 130

Scienmag

JULY 15, 2021

Credit: Courtesy of Klaudia Ciurkot Scientists have uncovered a way to control many genes in engineered yeast cells, opening the door to more efficient and sustainable production of bio-based products.

Production 97

Production Engineer Gene Scientist 97

Pharmaceutical Technology

APRIL 17, 2023

In this collaboration, Genmab and argenx will use their proprietary antibody technologies to develop and commercialise new products. argenx engineers antibodies for therapeutic use in its Immunology Innovation Program (IIP). argenx engineers antibodies for therapeutic use in its Immunology Innovation Program (IIP).

Antibody 130

Antibody Engineer FDA Approval Development 130

Medical Xpress

APRIL 20, 2023

Progressive loss of neurons is the underlying cause for a diverse spectrum of severe diseases called neurodegenerative diseases, which include Parkinson's disease, amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa.

Engineer 105

Engineer Production Development 105

Pharmaceutical Technology

JUNE 10, 2023

CIGB-128 is under clinical development by Center for Genetic Engineering and Biotechnology and currently in Phase I for Brain Tumor. According to GlobalData, Phase I drugs for Brain Tumor does not have sufficient historical data to build an indication benchmark PTSR for Phase I.

Genetic Engineering 100

Genetic Engineering Engineer Genetics Clinical Trials 100

Pharmaceutical Technology

JUNE 10, 2023

CIGB-128 is under clinical development by Center for Genetic Engineering and Biotechnology and currently in Phase I for Brain Tumor. According to GlobalData, Phase I drugs for Brain Tumor does not have sufficient historical data to build an indication benchmark PTSR for Phase I.

Genetic Engineering 100

Genetic Engineering Engineer Genetics Clinical Trials 100

Pharmaceutical Technology

JUNE 9, 2023

The US Food and Drug Administration (FDA) has granted approval to commence commercial production at Bristol Myers Squibb’s new advanced cell therapy manufacturing facility in Devens, Massachusetts. Each engineered T cell batch is manufactured separately and infused back into the cancer patient.

FDA Approval 130

FDA Approval Production Gene Therapy Manufacturing 130

Pharmaceutical Technology

SEPTEMBER 5, 2022

The National Medical Products Administration of China (NMPA) has approved CanSino Biologics ’ (CanSinoBIO) recombinant Covid-19 vaccine (Adenovirus Type 5 Vector) for inhalation, Convidecia Air, as a booster. This vaccine leverages the same adenovirus vector technological platform as Convidecia, the intramuscular version.

Vaccine 264

Vaccine Vaccination Genetic Engineering Clinical Trials 264

Pharmaceutical Technology

JANUARY 6, 2023

Formulating products that have the proper composition, viscosity, texture, and stability, and can also be shown to be safe and effective, is both a science and an art. Without proper precautions, knowledge gaps can occur and important details may be overlooked when a product is transferred from one site to another. Simplicity matters.

Production 130

Production Manufacturing Development Bioequivalency 130

Pharmaceutical Technology

NOVEMBER 7, 2022

As a vertically integrated company, SHL Medical prides itself on being an end-to-end partner, offering in-house capabilities at every stage – from design, development and production to final assembly, labelling and packaging. The company’s most prominent products are its autoinjectors, which are seeing growing global demand.

Production 130

Production Life Science Manufacturing Drug Delivery Systems 130

Pharmaceutical Technology

DECEMBER 19, 2022

On choosing the candidate, the company will oversee the complete development, production and marketing. As per the initial agreement, Sanofi is in charge of these products’ development, manufacturing and marketing while Innate Pharma is entitled to get up to $423.3m (€400m) in development and commercial milestone payments.

Development 264

Development Engineer Clinical Trials Clinical Trials 264

Pharmaceutical Technology

JUNE 29, 2022

For hundreds of years, we have found myriad uses for microbial enzymes in manufacturing – from food, drink, and household products to a range of industrial applications. In 2021, Novo Nordisk Pharmatech, a leading pharmaceutical-grade insulin and Quats product supplier announced plans to enter the enzyme market.

Drugs 295

Drugs Gene Therapy Production Manufacturing 295

XTalks

MARCH 4, 2022

Ziscuit, an online grocery search engine, allows food insecure customers and those that reside in food deserts to find the best-priced food items located near them. The grocery search engine was founded by Mark Peterson, an Alabama native who watched his mother struggle to afford weekly groceries.

Engineer 96

Engineer Production 96

XTalks

APRIL 10, 2025

This years honorees tackle the sectors biggest challenges: cutting waste, boosting nutrition and engineering better flavor without compromise. Fast Company also flagged four foodtech trends to likely define 2025: personalized nutrition powered by data, AIenabled product development, alternativeprotein scaleup and robotics in processing.

Protein 93

Protein Packaging Packaging Branding 93

XTalks

JANUARY 29, 2025

Highlights include expansion of biotech operations in Philadelphia, acquisition of a new pharma-device facility near Dublin, Ireland, and a new Center of Excellence for advanced drug delivery and drug-device combination product assembly in Rockford, Illinois.

Drug Delivery 52

Drug Delivery Production Packaging Packaging 52

STAT News

APRIL 17, 2023

Genetic engineering has the potential to transform how we raise animals for meat and other products, making food safer, improving animal health and welfare, and shrinking animal agriculture’s environmental footprint. Pigs that are less likely to induce allergic reactions in humans.

Genome 98

Genome Genomics Genetic Engineering Production 98

Pharmaceutical Technology

APRIL 5, 2023

Proxygen will receive royalties on net sales of products developed under the partnership. The company has developed a discovery engine that supports the identification of molecular glue degraders against difficult-to-drug or completely undruggable targets.

Development 246

Development Engineer Sales Research 246

Pharmaceutical Technology

APRIL 17, 2023

Prometheus Biosciences uses precision medicine to discover, develop and commercialise new therapeutic and companion diagnostic products to treat immune-mediated diseases. The company will buy all of Prometheus Biosciences’ outstanding shares for $200 a share through a subsidiary.

Engineer 262

Engineer Trials Antibody Development 262

Pharmaceutical Technology

JANUARY 5, 2023

Under the multi-year strategic partnership, Prevail will detect and advance capsids, which are clinically translatable, along with its cargo to develop the transformative genetic medicines by using Capsida’s novel adeno-associated virus (AAV) engineering platform.

Gene Therapy 237

Gene Therapy Gene Development Engineer 237

Pharmaceutical Technology

JUNE 24, 2022

The protein-based vaccine is engineered from the genetic sequence of the SARS-CoV-2 virus’ initial strain. Earlier this month, the US FDA’s Vaccines and Related Biological Products Advisory Committee (VRBPAC) voted 21 to 0 recommending the EUA grant for Novavax’s NVX-CoV2373 for individuals aged 18 years and above.

Vaccine 263

Vaccine Vaccination Clinical Trials Clinical Trials 263

Pharmaceutical Technology

JULY 25, 2022

But this also reflects a wider trend within the broader market, which is moving towards complex biological and non-biological products, he adds. Supply chain issues also come into play, meaning that owning proprietary API production is an advantage, he says. Thus, manufacturers stand to gain greater profit margins over a longer period.

Drugs 298

Drugs Manufacturing Production Marketing 298

Pharmaceutical Technology

MARCH 29, 2023

The company will also have the option to lead late-stage development and commercialisation activities on all products across the world. Sonoma will retain rights to co-promote the products in the US, as well as complete ownership of SBT-77-7101, its lead cell therapy candidate, and other programmes currently in development.

Development 245

Development Gene Therapy Gene Production 245

BioPharma Reporter

OCTOBER 6, 2021

Absci Corp, a synthetic biology firm, is partnering with pharma company, EQRx, to jointly engineer and develop several clinical candidates across multiple therapeutic areas, including oncology and immunology.

Protein 96

Protein Pharma Companies Production Engineer 96

Pharmaceutical Technology

OCTOBER 6, 2022

In order to plug the gap between demand and capacity and win back their competitive advantage, many pharmaceutical and fine chemical companies are turning to pre-engineered, end-to end providers to fulfil their API demand. While pre-engineered and modular facilities are not a new idea, every turnkey project installation is unique.

Engineer 130

Engineer Containment Production Manufacturing 130

Pharmaceutical Technology

DECEMBER 8, 2022

The delivery of the product is anticipated to begin early next year. It is created by taking T cells from the patient’s blood and then engineered in the laboratory to express chimeric antigen receptors. . Directed against a cell membrane protein called CD19, Yescarta uses the immune system of the patient to destroy cancer.

Licensing 305

Licensing Licensing Gene Therapy Gene 305

World of DTC Marketing

SEPTEMBER 15, 2021

During the pandemic, DTC commercials have pretty much remained the same as having product websites. Sure your product may lower A1C, but is that alone enough to get someone to schedule a telehealth visit with their doctor? DTC needs to reach out to audiences to motivate them to ask for a product.

Doctor 199

Doctor Doctors Production Pharma Companies 199

Pharma Mirror

OCTOBER 29, 2021

Telstar will be actively participating at CPhI, to be held in Milan, during 9-11th November 2021, promoting its personalized GMP consultancy & engineering reply to the new trends in pharma.

Engineer 130

Engineer Compliance Manufacturing Production 130

Pharmaceutical Technology

AUGUST 18, 2022

Furthermore, Sanofi will make tiered royalty payments on products that are developed under this partnership. Sanofi Research global head and chief scientific officer Frank Nestle said: “At Sanofi, we are committed to bringing higher quality medicines to patients faster, empowered by our advanced AI drug discovery engine.

Drugs 246

Drugs Engineer Medicine Sales 246

Pharmaceutical Technology

MAY 25, 2023

ElevateBio has raised $401m in a Series D financing round for advancing its technology platforms to expedite the design, production and development of cell and gene therapies. The technology platforms include the Life Edit gene editing platform, an RNA, cell, protein, vector engineering and induced pluripotent stem cells (iPSCs) platform.

Gene Therapy 243

Gene Therapy Gene Gene Editing Development 243

Pharmaceutical Technology

MARCH 8, 2023

The new technologies will also overcome the manufacturing bottlenecks in delivering advanced engineered cell products. This Beacon’s focus will be on product solutions that help address the bottlenecks impacting manufacturing yield and quality of cell therapies. The University of Pennsylvania Immunotherapy Richard W.

Gene Therapy 244

Gene Therapy Manufacturing Gene Production 244

World of DTC Marketing

SEPTEMBER 18, 2020

Most often, patients relied on the internet (specifically multiple myeloma websites [94%] and general search engines [92%] to find information about multiple myeloma). Oncology DTC needs to distinguish the key benefits of products in terms that patients will understand.

Production 259

Production Engineer Doctor Doctors 259

Scienmag

JULY 14, 2021

Credit: The University of Texas at Austin Urea is a critical element found in everything from fertilizers to skin care products. Large-scale production of urea, which is naturally a product of human urine, is a massive undertaking, making up about 2% of global energy use and emissions today.

Engineer 98

Engineer Production Scientist 98

Pharma Mirror

JUNE 11, 2024

By Michael von Papen, Chief Expert at Pharmatec GmbH – a Syntegon Company When a leading global collagenase manufacturer wants to renew and optimize a system at the heart of its production, technical expertise, and engineering competence is paramount. Moreover, cooperation within the project team needs to be well organized.

Engineer 130

Engineer Manufacturing Production 130

STAT News

NOVEMBER 15, 2022

The shot engineered by Bharat Biotech was, in part, an important effort to create a home-grown product that could   bolster the fortunes of the Indian pharmaceutical industry.

Vaccine 145

Vaccine Vaccination Engineer Clinical Trials 145

Pharmaceutical Technology

AUGUST 25, 2022

The development and usage of innovative technologies, as well as expertise from the selection of cells and genetic modification to intelligent automation of production and information technology systems, will be part of the centre. A cGMP-compliant production facility will be housed at the centre for manufacturing cell products at scale.

Manufacturing 130

Manufacturing Engineer Gene Therapy Production 130

Pharmaceutical Technology

SEPTEMBER 14, 2022

As an autologous cell therapy, manufacturing the infusion product is a highly specialised process involving tumour harvest and the extraction and large-scale ex vivo expansion of TILs. The use of engineered immune cytokines that selectively induce the expansion of TILs is being investigated as an alternative to IL-2 stimulation.

Immune Response 246

Immune Response In-Vivo Production Manufacturing 246