Pharmaceutical Technology

MARCH 11, 2024

is revolutionizing adoptive cell transfer therapies with patented methods to reduce HLA-A protein expression in engineered human cells. Discover how Intellia Therapeutics Inc. Explore the potential for treating cancer, infectious diseases, and autoimmune disorders.

Protein 130

Protein Genetics Engineer 130

Roots Analysis

SEPTEMBER 9, 2024

Over the years, pharmaceutical companies have shifted their priorities from traditional interventions towards more advanced pharmacological strategies, such as protein therapeutics. Further, $400 billion is the anticipated sales of protein-based therapeutics in 2023. The mRNA is then translated into to form functional proteins.

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Protein Gene Production DNA 40

Scienmag

JANUARY 6, 2022

Protein assembly is essential for the formation of ordered biological structures, but imagine engineering one! This is exactly what researchers at Tokyo Tech have now accomplished with protein needles.

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Protein Engineer Regulation Research 79

Pharma Times

DECEMBER 20, 2023

Researchers from Johns Hopkins University School of Medicine have revealed new findings about a key pathological protein associated with Parkinson’s disease (PD), which could lead to new treatments. Estimated to affect over 8.5 However, its relation to dopaminergic neuron death is unclear.

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Protein Medicine Engineer Genetics 93

BioTech 365

OCTOBER 11, 2021

FC (Fragment Crystallizable) Protein and Glyco-engineered Antibodies Market, 2030 – ResearchAndMarkets.com FC (Fragment Crystallizable) Protein and Glyco-engineered Antibodies Market, 2030 – ResearchAndMarkets.com DUBLIN–(BUSINESS WIRE)–The “Fc Protein and Glyco-engineered Antibodies Market: Focus on Type of Fc Engineering (..)

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Engineer Protein Antibody Marketing 40

Scienmag

NOVEMBER 17, 2021

Chemical topology is a unique dimension for protein engineering. Over the past few years, the discovery of topological nontrivial proteins in nature has already revealed their many potential functional benefits, such as enhanced thermal/mechanical/chemical stability.

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Protein Antibody Engineer Development 80

BioTech 365

JANUARY 6, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: How engineered protein patches could boost immunotherapy.How engineered protein patches could boost immunotherapy aliu Wed, 01/06/2021 – 04:38 from FierceBiotech: Biotech [link].

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Engineer Protein Research 40

Scienmag

JANUARY 6, 2021

Proteins engineered to form honeycomb structures can block uptake of receptors from the surface of cells Credit: Ian Haydon, UW Medicine Institute for Protein Design A new class of protein material that interacts with living cells without being absorbed by them can influence cell signaling, a new study shows.

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Protein Engineer Medicine 84

Medical Xpress

DECEMBER 5, 2022

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

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Protein Genetic Engineering Research Engineer 75

Scienmag

JULY 7, 2022

Balancing how much protein you eat with the amount your body needs could reduce nitrogen releases to aquatic systems in the U.S. Credit: Courtesy Maya Almaraz Balancing how much protein you eat with […]. by 12% and overall nitrogen losses to air and water by 4%, according to a study from the University of California, Davis.

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Protein Engineer 85

The Pharma Data

MAY 19, 2023

HIGH SCHOOL SCIENTISTS AND ENGINEERS WIN NEARLY $9 MILLION AT THE REGENERON INTERNATIONAL SCIENCE AND ENGINEERING FAIR 2023 Regeneron Pharmaceuticals, Inc. ” Regeneron ISEF provides a global stage for the best and brightest young scientists and engineers around the world.

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Engineer Scientist Protein Research 52

BioTech 365

OCTOBER 8, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Deep-learning algorithm aims to accelerate protein engineering.Proteins are the molecular machines of all living cells and have been exploited for use in many applications, including therapeutics and … Continue reading → (..)

Protein 40

Protein Engineer Research 40

Scienmag

JULY 15, 2021

New artificial intelligence software can compute protein structures in 10 minutes Credit: Ian Haydon, UW Medicine Institute for Protein Design Scientists have waited months for access to highly accurate protein structure prediction since DeepMind presented remarkable progress in this area at the 2020 Critical Assessment of Structure Prediction, or (..)

Protein 98

Protein Scientist Medicine Engineer 98

XTalks

FEBRUARY 29, 2024

Dual-function fusion proteins represent a cutting-edge approach in biopharmaceutical research, offering a promising avenue for the development of novel therapeutics in the treatment of complex diseases such as cancer and autoimmune disorders. At the helm of this venture is Dr. Taylor H. How is your lead program differentiated?

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Protein Development Clinical Trials Clinical Trials 67

XTalks

MARCH 31, 2023

By growing high quality crystal structures of protein-based therapeutics under microgravity, researchers can gain better insights into their complex structures and stability. The proteins will be analyzed back on Earth using techniques such as X-ray diffraction and compared with crystals from the same biologics grown on Earth.

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Protein Research Development Manufacturing 77

Scienmag

FEBRUARY 14, 2022

Researchers at the University of Toronto have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.

Protein 87

Protein Research Engineer 87

BioPharma Reporter

NOVEMBER 23, 2023

Cradle, the biotech startup using generative AI to help scientists design and engineer proteins, has raised $24 million in Series A funding.

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Engineer Protein Scientist Regulation 104

Scienmag

NOVEMBER 9, 2021

Osaka, Japan – One degree (Celsius) can make a difference: a team of investigators led by Osaka University has demonstrated regulation of a critical protein complex that occurs only at physiological temperature. Credit: Hiroaki Kubota et al.

Protein 83

Protein Regulation Engineer 83

Scienmag

MARCH 10, 2022

Close interactions with infectious disease set both University of California, Santa Cruz graduate student Ana Nuñez Castrejon and Associate Professor of Biomolecular Engineering Rebecca DuBois on the path of studying Respiratory syncytial virus (RSV), a common and sometimes dangerous respiratory disease for which there is not currently a vaccine.

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Immune Response Vaccination Vaccine Protein 77

Scienmag

MARCH 29, 2021

Credit: The Protein Society The Protein Society, the premier international society dedicated to supporting protein research, announces the winners of the 2021 Protein Society Awards, which will be conferred at the 35th Anniversary Symposium (virtual), July 7 – 14, 2021.

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Protein Research Engineer 73

Scienmag

MARCH 30, 2022

Russian researchers and their international collaborators have developed a full-function bioelectronic photocell using one molecule of a fluorescent protein attached to a carbon nanotube. The […].

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Protein Genetics Development Research 69

XTalks

AUGUST 8, 2024

Tecelra is the first cell therapy engineered for a solid tumor cancer in the US, offering a new option for patients with specific genetic markers who have previously undergone chemotherapy. Tecelra works by using the patient’s own immune system to target tumors expressing the melanoma-associated antigen A4 (MAGE-A4) protein on cancer cells.

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Engineer Clinical Trials Clinical Trials FDA Approval 52

BioTech 365

JANUARY 27, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers reveal recipe for engineering ribosomes.Ribosomes are complex molecular machines in the cell that catalyze the production of proteins.

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Engineer Research Protein Production 40

Scienmag

NOVEMBER 11, 2020

Credit: Masato Kanemaki Researchers can now more accurately and precisely target specific proteins in yeast, mammalian cells and mice to study how knocking down specific protein traits can influence physical manifestation in a cell or organism. The Japan-based team published their results on November 11th in Nature Communications.

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Protein Genetics RNA Development 98

BioPharma Reporter

OCTOBER 6, 2021

Absci Corp, a synthetic biology firm, is partnering with pharma company, EQRx, to jointly engineer and develop several clinical candidates across multiple therapeutic areas, including oncology and immunology.

Protein 102

Protein Pharma Companies Engineer Production 102

Scienmag

JULY 12, 2021

The function of a protein can depend on its abundance in a cell. So, when investigating the properties of a new protein, it is essential to make sure that the same amount is produced by every cell. Researchers at Baylor College of Medicine and Rice University have found a new way to do just that […].

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Gene Expression Engineer Gene Protein 63

Scienmag

JULY 20, 2021

Artificially designed, amyloid-silk hybrid protein developed in Zhang lab even outperforms some spider silks Credit: Washington University in St. Now engineers at Washington University in St. Louis have designed amyloid silk hybrid proteins and produced them in engineered […].

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Engineer Protein Development Research 98

Scienmag

OCTOBER 12, 2020

Potential new antibiotics work by disrupting bacterial membrane and summoning immune cells in animal models PHILADELPHIA–A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom.

Bacteria 40

Bacteria Engineer Scientist Medicine 40

Scienmag

JULY 15, 2021

Researchers present RoseTTAFold – a neural network approach for protein modeling with accuracies near those of what DeepMind’s AlphaFold2 has achieved, according to a new study. Proteins are the building blocks of life […].

Protein 74

Protein Research Engineer 74

BioTech 365

DECEMBER 7, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: A light in the dark tissue: Switchable proteins for biomedical imaging.Dr. Stiel leads the group for Cell Engineering at the Institute of Biological and Medical … Continue reading →

Protein 40

Protein Engineer Research 40

Scienmag

JUNE 18, 2021

Neuroinflammatory response-induced proteases impede the recovery process from brain injury; novel interactions between proteins (hevin and calcyon) help in the recovery of neurons in a mature brain Credit: Korea Institute of Science and Technology(KIST) Patients with brain injury (caused by stroke or trauma) primarily rely on rehabilitation therapy (..)

Protein 93

Protein Engineer Medicine 93

Scienmag

JULY 11, 2021

Johns Hopkins researchers describe protein regulating key step in cancer metastasis Credit: Johns Hopkins University Researchers have identified a specialized protein that appears to help prevent tumor cells from entering the bloodstream and spreading to other parts of the body.

Protein 69

Protein Regulation Research Engineer 69

pharmaphorum

MAY 12, 2021

UK biotech MiNA Therapeutics has signed up another big pharma partner for its small activating RNA (saRNA) platform, which upregulates the activity of proteins, with Eli Lilly the latest to get in on the action. . The post Lilly buys into MiNA’s protein-boosting RNA tech in $1.25bn deal appeared first on.

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RNA Protein Drugs Pharma Companies 63

The Pharma Data

MARCH 23, 2022

Polymerase is a viral protein that directs how Ebola virus replicates its genome as it infects new hosts. The researchers discovered that Ebola virus polymerase hijacks a cellular protein called GSPT1. To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase.

Protein 52

Protein Genome Genomics Research 52

Pharmaceutical Technology

JUNE 24, 2022

The protein-based vaccine is engineered from the genetic sequence of the SARS-CoV-2 virus’ initial strain. Developed utilising Novavax’s recombinant nanoparticle technology to generate antigen obtained from the coronavirus spike (S) protein, the vaccine is also formulated with the company’s saponin-based Matrix-M adjuvant.

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Vaccination Vaccine Clinical Trials Clinical Trials 263

Scienmag

FEBRUARY 23, 2021

(February 23, 2021) – The Gates Biomanufacturing Facility (GBF) has completed the manufacturing and release of a protein-based biologic under Good Manufacturing Practice for Phase 1 Investigational Drugs for first-in-human clinical trials.

Protein 57

Protein Manufacturing Clinical Trials Clinical Trials 57

Scienmag

DECEMBER 2, 2020

Credit: University of Leeds A visualisation made from nearly 100,000 electron microscope images has revealed the ingenious way a protein involved in muscle activity shuts itself down to conserve energy.

Protein 53

Protein Engineer 53