Scienmag

JANUARY 6, 2022

Protein assembly is essential for the formation of ordered biological structures, but imagine engineering one! This is exactly what researchers at Tokyo Tech have now accomplished with protein needles.

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Scienmag

JANUARY 6, 2021

Proteins engineered to form honeycomb structures can block uptake of receptors from the surface of cells Credit: Ian Haydon, UW Medicine Institute for Protein Design A new class of protein material that interacts with living cells without being absorbed by them can influence cell signaling, a new study shows.

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Pharmaceutical Technology

JUNE 24, 2022

The protein-based vaccine is engineered from the genetic sequence of the SARS-CoV-2 virus’ initial strain. Developed utilising Novavax’s recombinant nanoparticle technology to generate antigen obtained from the coronavirus spike (S) protein, the vaccine is also formulated with the company’s saponin-based Matrix-M adjuvant.

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Scienmag

NOVEMBER 17, 2021

Chemical topology is a unique dimension for protein engineering. Over the past few years, the discovery of topological nontrivial proteins in nature has already revealed their many potential functional benefits, such as enhanced thermal/mechanical/chemical stability.

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Pharmaceutical Technology

MARCH 11, 2024

is revolutionizing adoptive cell transfer therapies with patented methods to reduce HLA-A protein expression in engineered human cells. Discover how Intellia Therapeutics Inc. Explore the potential for treating cancer, infectious diseases, and autoimmune disorders.

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Pharma Times

FEBRUARY 10, 2025

New methodology may boost innovation in protein engineering

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pharmaphorum

NOVEMBER 29, 2023

Start-up Cradle tucks in $24m for protein engineering AI Phil.Taylor Wed, 29/11/2023 - 11:48 Bookmark this

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Scienmag

JULY 15, 2021

New artificial intelligence software can compute protein structures in 10 minutes Credit: Ian Haydon, UW Medicine Institute for Protein Design Scientists have waited months for access to highly accurate protein structure prediction since DeepMind presented remarkable progress in this area at the 2020 Critical Assessment of Structure Prediction, or (..)

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Protein Scientist Medicine Engineer 98

XTalks

JANUARY 7, 2025

Symvess is a one-time, single-use, acellular tissue-engineered vessel (ATEV) composed of human extracellular matrix proteins. Manufactured using vascular smooth muscle cells derived from human aortic tissue, Symvess offers a novel solution for patients with traumatic vascular injuries.

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Pharmaceutical Technology

SEPTEMBER 5, 2022

Administered as a single dose, the genetically engineered vaccine has the replication-defective adenovirus type 5 vector that expresses the spike S protein of the SARS-CoV-2 virus. In May, CanSinoBIO received an emergency use listing (EUL) from the World Health Organization (WHO) for its recombinant Covid-19 shot, Convidecia.

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Medical Xpress

DECEMBER 5, 2022

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

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Scienmag

NOVEMBER 11, 2020

Credit: Masato Kanemaki Researchers can now more accurately and precisely target specific proteins in yeast, mammalian cells and mice to study how knocking down specific protein traits can influence physical manifestation in a cell or organism. The Japan-based team published their results on November 11th in Nature Communications.

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Scienmag

JULY 7, 2022

Balancing how much protein you eat with the amount your body needs could reduce nitrogen releases to aquatic systems in the U.S. Credit: Courtesy Maya Almaraz Balancing how much protein you eat with […]. by 12% and overall nitrogen losses to air and water by 4%, according to a study from the University of California, Davis.

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Protein Engineer 85

XTalks

MARCH 31, 2023

By growing high quality crystal structures of protein-based therapeutics under microgravity, researchers can gain better insights into their complex structures and stability. The proteins will be analyzed back on Earth using techniques such as X-ray diffraction and compared with crystals from the same biologics grown on Earth.

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Scienmag

JULY 20, 2021

Artificially designed, amyloid-silk hybrid protein developed in Zhang lab even outperforms some spider silks Credit: Washington University in St. Now engineers at Washington University in St. Louis have designed amyloid silk hybrid proteins and produced them in engineered […].

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Scienmag

FEBRUARY 14, 2022

Researchers at the University of Toronto have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.

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Protein Research Engineer 87

BioPharma Reporter

OCTOBER 6, 2021

Absci Corp, a synthetic biology firm, is partnering with pharma company, EQRx, to jointly engineer and develop several clinical candidates across multiple therapeutic areas, including oncology and immunology.

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Protein Pharma Companies Production Engineer 96

Scienmag

NOVEMBER 9, 2021

Osaka, Japan – One degree (Celsius) can make a difference: a team of investigators led by Osaka University has demonstrated regulation of a critical protein complex that occurs only at physiological temperature. Credit: Hiroaki Kubota et al.

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Protein Regulation Engineer 83

XTalks

MAY 7, 2021

As Novavax awaits emergency use authorization (EUA) from the US Food and Drug Administration (FDA) for its protein-based COVID-19 vaccine NVX-CoV2373, the company shared new data this week on the vaccine’s efficacy against the South African B.1.351 1.351 variant.

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Scienmag

JUNE 18, 2021

Neuroinflammatory response-induced proteases impede the recovery process from brain injury; novel interactions between proteins (hevin and calcyon) help in the recovery of neurons in a mature brain Credit: Korea Institute of Science and Technology(KIST) Patients with brain injury (caused by stroke or trauma) primarily rely on rehabilitation therapy (..)

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Protein Engineer Medicine 93

XTalks

FEBRUARY 29, 2024

Dual-function fusion proteins represent a cutting-edge approach in biopharmaceutical research, offering a promising avenue for the development of novel therapeutics in the treatment of complex diseases such as cancer and autoimmune disorders. At the helm of this venture is Dr. Taylor H. How is your lead program differentiated?

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Scienmag

MARCH 29, 2021

Credit: The Protein Society The Protein Society, the premier international society dedicated to supporting protein research, announces the winners of the 2021 Protein Society Awards, which will be conferred at the 35th Anniversary Symposium (virtual), July 7 – 14, 2021.

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BioPharma Reporter

NOVEMBER 23, 2023

Cradle, the biotech startup using generative AI to help scientists design and engineer proteins, has raised $24 million in Series A funding.

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Engineer Protein Scientist Regulation 101

Scienmag

MARCH 10, 2022

Close interactions with infectious disease set both University of California, Santa Cruz graduate student Ana Nuñez Castrejon and Associate Professor of Biomolecular Engineering Rebecca DuBois on the path of studying Respiratory syncytial virus (RSV), a common and sometimes dangerous respiratory disease for which there is not currently a vaccine.

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Pharmaceutical Technology

DECEMBER 8, 2022

Directed against a cell membrane protein called CD19, Yescarta uses the immune system of the patient to destroy cancer. It is created by taking T cells from the patient’s blood and then engineered in the laboratory to express chimeric antigen receptors. .

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Scienmag

JULY 15, 2021

Researchers present RoseTTAFold – a neural network approach for protein modeling with accuracies near those of what DeepMind’s AlphaFold2 has achieved, according to a new study. Proteins are the building blocks of life […].

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Protein Research Engineer 74

pharmaphorum

MAY 12, 2021

UK biotech MiNA Therapeutics has signed up another big pharma partner for its small activating RNA (saRNA) platform, which upregulates the activity of proteins, with Eli Lilly the latest to get in on the action. . The post Lilly buys into MiNA’s protein-boosting RNA tech in $1.25bn deal appeared first on.

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Pharmaceutical Technology

JUNE 21, 2023

Hemgenix works by dosing a patient with an engineered adeno-associated virus (AAV), containing the gene responsible for producing a protein called factor IX. This protein helps to form blood clots and stop bleeding, with haemophilia B arising when the body is partially or completely unable to produce it.

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Scienmag

MARCH 30, 2022

Russian researchers and their international collaborators have developed a full-function bioelectronic photocell using one molecule of a fluorescent protein attached to a carbon nanotube. The […].

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Protein Genetics Development Research 69

Pharmaceutical Technology

APRIL 20, 2023

In addition to new regulatory functionalities, this feature may result in stronger and more durable protein expression. CircAde is said to be the most advanced therapeutic concept, and leverages the company’s experience in oncolytic viruses to use engineered adenoviruses to deliver circRNA to cancer cells.

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Pharmaceutical Technology

FEBRUARY 14, 2023

Novavax president and CEO John Jacobs said: “This agreement acknowledges the need to offer the American people a diverse Covid-19 vaccine portfolio and underscores the importance of Novavax’s partnership with the US Government to ensure continuous access to a protein-based option as part of public health measures. “We

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Vaccination Vaccine Protein Engineer 162

Scienmag

JULY 12, 2021

The function of a protein can depend on its abundance in a cell. So, when investigating the properties of a new protein, it is essential to make sure that the same amount is produced by every cell. Researchers at Baylor College of Medicine and Rice University have found a new way to do just that […].

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Pharmaceutical Technology

MAY 25, 2023

The technology platforms include the Life Edit gene editing platform, an RNA, cell, protein, vector engineering and induced pluripotent stem cells (iPSCs) platform. ElevateBio intends to use the funds to advance its genetic medicine current good manufacturing practice (cGMP) and process development business, BaseCamp.

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Pharmaceutical Technology

JUNE 29, 2022

Specialty enzymes are proteins that can act as very specific biocatalysts to accelerate reactions and produce the desired target molecule in pharmaceuticals,” explains Kristoffer Laursen, Head of R&D at Novo Nordisk Pharmatech. “In In the evolving biotechnology industry, enzymes are important process aids.

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Scienmag

JULY 11, 2021

Johns Hopkins researchers describe protein regulating key step in cancer metastasis Credit: Johns Hopkins University Researchers have identified a specialized protein that appears to help prevent tumor cells from entering the bloodstream and spreading to other parts of the body.

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Protein Regulation Research Engineer 69

BioPharma Reporter

MAY 10, 2021

Endless RNA is a novel, engineered form of RNA that can be programmed to express therapeutic proteins inside the body: âa groundbreaking therapeutic platform capable of biological applications we could only dream of a few years ago,â according to the founders.

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RNA Engineer Medicine Protein 98

Pharmaceutical Technology

JUNE 23, 2022

It functions as a molecular scissor by slicing long chains of virus’ polypeptide proteins into smaller component proteins. These viruses can develop rapid defences at the cellular level by orchestrating these layers, or folding mechanisms, in viral proteins so the key is to find a way to shut them down.”.

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