Scienmag

FEBRUARY 14, 2022

Researchers at the University of Toronto have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.

Protein 87

Protein Research Engineer 87

Scienmag

NOVEMBER 11, 2020

Credit: Masato Kanemaki Researchers can now more accurately and precisely target specific proteins in yeast, mammalian cells and mice to study how knocking down specific protein traits can influence physical manifestation in a cell or organism. “Conditional gene knockout and small interfering RNA […].

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Protein Genetics RNA Development 98

Pharmaceutical Technology

NOVEMBER 29, 2022

Researchers at City of Hope in the US have developed a new potential therapy to treat glioblastoma multiforme (GBM), a kind of brain cancer. For this approach, the team leveraged an oncolytic herpes simplex virus for releasing chemokines, which are signalling proteins that aid in attracting immune cells to tumours.

Development 130

Development Research Antibody Engineer 130

pharmaphorum

NOVEMBER 26, 2020

The headline news in the new agreement is the formation of a joint AI Innovation Lab – split between InstaDeep’s headquarters in London in the UK and BioNTech’s site in Mainz Germany – that will focus on drug discovery and design, protein engineering, manufacturing and supply chain.

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Research Protein Engineer Manufacturing 105

Scienmag

JULY 20, 2021

Artificially designed, amyloid-silk hybrid protein developed in Zhang lab even outperforms some spider silks Credit: Washington University in St. Now engineers at Washington University in St. Louis have designed amyloid silk hybrid proteins and produced them in engineered […].

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Engineer Protein Development Research 98

Scienmag

AUGUST 20, 2020

Some of these structures, such as those found in DNA, RNA and proteins, are formed through complex molecular interactions that are not easily duplicated by inorganic materials. A research team led by Richard Robinson, associate professor of materials science and engineering, discovered a […].

Research 75

Research RNA DNA Engineer 75

BioTech 365

JANUARY 6, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: How engineered protein patches could boost immunotherapy.How engineered protein patches could boost immunotherapy aliu Wed, 01/06/2021 – 04:38 from FierceBiotech: Biotech [link].

Engineer 40

Engineer Protein Research 40

Scienmag

MARCH 29, 2021

Credit: The Protein Society The Protein Society, the premier international society dedicated to supporting protein research, announces the winners of the 2021 Protein Society Awards, which will be conferred at the 35th Anniversary Symposium (virtual), July 7 – 14, 2021.

Protein 73

Protein Research Engineer 73

XTalks

FEBRUARY 29, 2024

Dual-function fusion proteins represent a cutting-edge approach in biopharmaceutical research, offering a promising avenue for the development of novel therapeutics in the treatment of complex diseases such as cancer and autoimmune disorders. My initial exposure to medicine came through bench research.

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Protein Development Clinical Trials Clinical Trials 94

XTalks

MAY 7, 2021

As Novavax awaits emergency use authorization (EUA) from the US Food and Drug Administration (FDA) for its protein-based COVID-19 vaccine NVX-CoV2373, the company shared new data this week on the vaccine’s efficacy against the South African B.1.351 Glenn, president of research and development at Novavax, in a news release. “It

Protein 97

Protein Vaccination Vaccine Trials 97

Scienmag

MARCH 10, 2022

Close interactions with infectious disease set both University of California, Santa Cruz graduate student Ana Nuñez Castrejon and Associate Professor of Biomolecular Engineering Rebecca DuBois on the path of studying Respiratory syncytial virus (RSV), a common and sometimes dangerous respiratory disease for which there is not currently a vaccine.

Immune Response 77

Immune Response Vaccination Vaccine Protein 77

Pharmaceutical Technology

APRIL 20, 2023

In addition to new regulatory functionalities, this feature may result in stronger and more durable protein expression. CircRNA research and development activities are being conducted at the company’s facility at the Karolinska Institute in Stockholm, Sweden.

Gene Therapy 240

Gene Therapy RNA Gene Development 240

pharmaphorum

SEPTEMBER 16, 2022

Alphabet subsidiary and precision health company Verily recently announced a breakthrough in its AI drug discovery GPCR research collaboration with Sosei Heptares. Verily’s Immune Profiler platform is “a discovery engine consisting of proprietary immune profiling lab workflow, growing multi-omic database, and advanced analytical tools”.

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Development Research Drugs Clinical Trials 135

Scienmag

JULY 15, 2021

Researchers present RoseTTAFold – a neural network approach for protein modeling with accuracies near those of what DeepMind’s AlphaFold2 has achieved, according to a new study. Proteins are the building blocks of life […].

Protein 74

Protein Research Engineer 74

Pharmaceutical Technology

JUNE 23, 2022

Researchers at the University of New Hampshire (UNH) have found that a repurposed drug, CCG-50014, could hinder the activity of a key enzyme of the SARS-CoV-2 virus, which causes Covid-19. Mpro has become the main focus of intense research and treatment development as it is vital for viral replication.

Drugs 130

Drugs Protein Genome Genomics 130

Pharmaceutical Technology

MAY 25, 2023

The technology platforms include the Life Edit gene editing platform, an RNA, cell, protein, vector engineering and induced pluripotent stem cells (iPSCs) platform. New investors included research and development partner Novo Nordisk, Lee Family Office (Asia) and Woodline.

Gene Therapy 243

Gene Therapy Gene Gene Editing Development 243

Scienmag

MARCH 30, 2022

Russian researchers and their international collaborators have developed a full-function bioelectronic photocell using one molecule of a fluorescent protein attached to a carbon nanotube.

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Protein Genetics Development Research 69

Pharmaceutical Technology

FEBRUARY 14, 2023

The modified contract is backed by previously allocated federal funding from Biomedical Advanced Research and Development Authority, HHS, and the Administration for Strategic Preparedness and Response.

Vaccination 162

Vaccination Vaccine Protein Engineer 162

Scienmag

JULY 11, 2021

Johns Hopkins researchers describe protein regulating key step in cancer metastasis Credit: Johns Hopkins University Researchers have identified a specialized protein that appears to help prevent tumor cells from entering the bloodstream and spreading to other parts of the body.

Protein 69

Protein Regulation Research Engineer 69

Medical Xpress

MAY 16, 2023

and China engineered active immunotherapy to create smart nanovesicles for personalized treatment. In a new report in Science Advances, Kerui Wu and colleagues in the departments of cancer biology, translation biology and breast surgery in the U.S.,

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Engineer Protein Development Research 109

Scienmag

JULY 12, 2021

The function of a protein can depend on its abundance in a cell. So, when investigating the properties of a new protein, it is essential to make sure that the same amount is produced by every cell. Researchers at Baylor College of Medicine and Rice University have found a new way to do just that […].

Gene Expression 63

Gene Expression Engineer Gene Protein 63

Pharmaceutical Technology

APRIL 28, 2023

Generate Biomedicines has signed a co-development and commercialisation agreement with the University of Texas MD Anderson Cancer Center to expedite the development of new protein therapeutics for oncology using generative AI. It enables innovative and collaborative research to rapidly bring new treatment options to patients.

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Development Clinical Trials Clinical Trials Protein 130

BioTech 365

JANUARY 27, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers reveal recipe for engineering ribosomes.Ribosomes are complex molecular machines in the cell that catalyze the production of proteins.

Engineer 40

Engineer Research Protein Production 40

Scienmag

NOVEMBER 15, 2021

A Ludwig Cancer Research study has devised a highly efficient method to generate large numbers of immune cells specifically engineered to recognize neoantigens—small fragments of randomly mutated proteins that are typically unique to a patient’s cancer—and destroy the tumors that express them.

Engineer 87

Engineer Protein Research 87

Pharmaceutical Technology

OCTOBER 12, 2022

Nimbus Therapeutics and Eli Lilly and Company (Lilly) have signed a research partnership and licence agreement to develop and market new therapies that activate a specific AMPK isoform to treat metabolic diseases. The company will lead the research activities, while Lilly will undertake the global development and marketing activities.

Development 130

Development Protein Engineer Drugs 130

Scienmag

AUGUST 31, 2020

The researchers […]. A team led by a biomedical scientist at the University of California, Riverside has found a new mechanism responsible for the abnormal development of neuronal connections in the mouse brain that leads to seizures and abnormal social behaviors.

Protein 97

Protein Scientist Development Research 97

Pharmaceutical Technology

JUNE 4, 2023

There are two main genes in the AAV genome, rep and cap, which encode nine different proteins. Transcription of the rep gene is initiated from the p5 or p19 promoters to, respectively, produce the large (Rep78 and Rep68) and small (Rep52 and Rep40) nonstructural Rep proteins.

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Gene Gene Therapy Genetics DNA 262

Scienmag

MAY 27, 2021

Credit: SFU SFU computing science professor Ghassan Hamarneh is using his medical imaging analysis expertise to help UBC researchers understand the role of caveolin-1 (CAV1) in certain cancer types. CAV1 is a protein associated with poor outcomes in aggressive breast and prostate cancer.

Research 92

Research Protein Bioinformatics Engineer 92

Scienmag

AUGUST 10, 2020

Now, Salk researchers have developed a new imaging method that lets them […].

Protein 93

Protein Development Research Engineer 93

Scienmag

NOVEMBER 19, 2020

Credit: Meditech Gloves Cranfield University researchers in partnership with Meditech Gloves, one of the leading manufacturers of high-quality examination and surgical gloves, have shown how energy savings can be made with the development of more sustainable, biodegradable, protein-free, natural rubber gloves.

Manufacturing 82

Manufacturing Research Protein Development 82

Scienmag

MARCH 11, 2021

Proteins choreograph the infinitesimal dance of living cells and functional biomaterials Credit: Lehigh University | Thamma, Kowal, Falk, Jain An interdisciplinary research team at Lehigh University has unraveled how functional biomaterials rely upon an interfacial protein layer to transmit signals to living cells concerning their adhesion, proliferation (..)

Research 78

Research Protein Development Engineer 78

Roots Analysis

SEPTEMBER 9, 2024

Over the years, pharmaceutical companies have shifted their priorities from traditional interventions towards more advanced pharmacological strategies, such as protein therapeutics. Further, $400 billion is the anticipated sales of protein-based therapeutics in 2023. The mRNA is then translated into to form functional proteins.

Protein 40

Protein Gene Production DNA 40

Scienmag

FEBRUARY 23, 2021

(February 23, 2021) – The Gates Biomanufacturing Facility (GBF) has completed the manufacturing and release of a protein-based biologic under Good Manufacturing Practice for Phase 1 Investigational Drugs for first-in-human clinical trials.

Protein 57

Protein Manufacturing Clinical Trials Clinical Trials 57

BioTech 365

OCTOBER 8, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Deep-learning algorithm aims to accelerate protein engineering.Proteins are the molecular machines of all living cells and have been exploited for use in many applications, including therapeutics and … Continue reading → (..)

Protein 40

Protein Engineer Research 40

Scienmag

MAY 17, 2021

Revelations from a fly study could improve our understanding of protein malnutrition in humans.

Protein 52

Protein Hormones Research Engineer 52

The Pharma Data

MAY 19, 2023

HIGH SCHOOL SCIENTISTS AND ENGINEERS WIN NEARLY $9 MILLION AT THE REGENERON INTERNATIONAL SCIENCE AND ENGINEERING FAIR 2023 Regeneron Pharmaceuticals, Inc. Using her research, she says she found the smallest of these planets ever discovered. Kaitlyn Wang won first place and received the $75,000 George D.

Engineer 52

Engineer Scientist Protein Research 52

The Pharma Data

MARCH 23, 2022

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase. Polymerase is a viral protein that directs how Ebola virus replicates its genome as it infects new hosts. The researchers discovered that Ebola virus polymerase hijacks a cellular protein called GSPT1.

Protein 52

Protein Genome Genomics Research 52