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In 2021, the FDA granted approval to San Francisco-based Excision BioTherapeutics to start trials assessing CRISPR geneediting as a potential treatment for HIV. The noteworthy candidate, EBT-101, is designed to eliminate HIV proviral DNA using CRISPR-Cas9 along with two guide RNAs (gRNAs). In November 2023, Hookipa Pharma Inc.,
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Moderna’s COVID-19 vaccine triggers an immuneresponse in older adults. Freenome’s diagnostic searches for direct indication of tumors and signs of the immune system’s response, integrating genomics, transcriptomics, methylomics, and proteomics technologies.
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