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Vertex and CRISPR Therapeutics submit BLAs to FDA for exa-cel

Pharmaceutical Technology

Formerly known as CTX001, exa-cel is an investigational, autologous, ex vivo CRISPR/Cas9 gene-edited therapy. Vertex Pharmaceuticals chief medical officer and Global Medicines Development and Medical Affairs executive vice-president Carmen Bozic said: “The completion of our exa-cel global regulatory filings is a historic milestone. “We

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Biohacking is a response to societal problems, but is not the answer

Pharmaceutical Technology

It covers a broad range of techniques from the less invasive practice of intermittent fasting to drastic and invasive procedures, such as the implanting of microchips or injecting of gene-editing enzymes. nurses, doctors, and hospital auxiliary staff) to meet these needs.

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Strategies to Successfully Manage Complex Cell Therapy Clinical Trials

XTalks

Medpace has IP experience with both autologous and allogeneic cellular products, ex vivo and in vivo gene transfer, and a number of different gene-editing mechanisms. An overview of Medpace’s experience in conducting cell and gene therapy trials. Extensive knowledge of regional and country specific requirements.

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Are We Getting Closer to a Herpes Vaccine?

The Pharma Data

The gene edit prevents the virus from performing its normal evasive maneuver: hiding out in nervous system cells in order to elude the immune system. MONDAY, Nov. 16, 2020 — Scientists are reporting early success with an experimental herpes vaccine that uses a genetically modified version of the virus.