Remove Gene Expression Remove Genomics Remove Life Science
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Combining the Powers of Single Cell Sequencing and AI in Understanding Disease Biology and Drug Development

XTalks

The detailed complexity of these processes can be captured by creating models that combine correlates of gene and protein expression, providing insight into the molecular composition of tissues. Visium Spatial Gene Expression Solution. Feature barcoding using gel beads. Leading Innovations in Single Cell Technology.

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Aardvark Therapeutics IPO Sets Sights on Satiating Hyperphagia and Extreme Hunger

XTalks

More recently, MSN reported on a Cell Genomics study where CRISPR reactivated dormant genes in patient-derived cells, restoring normal gene expression and improving metabolic function an innovation that could address PWS at its genetic roots.

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Epigenetic Editing with CRISPR + ADHD in Preschoolers – Xtalks Life Science Podcast Ep. 10

XTalks

In this episode, Ayesha discusses a new tool that uses CRISPR to modulate gene expression without editing DNA sequences. Dubbed “CRISPRoff,” the technology targets the epigenome to silence genes involved in diseases, with applications in cancer, AML and other conditions with a heritable component.

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Epigenetic Editing with CRISPR Might Be Easier Than We Thought

XTalks

These modifications regulate gene expression without changing the sequence or structure of DNA. The tool could also prove to be safer than conventional CRISPR-based gene therapies as it does not involve DNA editing, and thus would not cause potentially harmful off-target genomic changes. Epigenetic Editing with CRISPR.

DNA 98
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International Women’s Day 2024: A Spotlight on 5 Women’s Health Webinars with Xtalks

XTalks

A new workflow from BioSkryb Genomics merges extensive data from whole genome sequencing (WGS) and the focused insights gained from small, targeted panels that emphasize druggable targets. Through this, researchers can pinpoint breast cancer cell types and their phenotypic states.

Genetics 115
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Using CRISPR to Edit the Epigenome Might Be Easier Than We Thought

XTalks

These modifications regulate gene expression without altering the sequence or structure of DNA. The tool could also prove to be safer than conventional CRISPR-based gene therapies as it does not involve DNA editing, and thus would not cause potentially harmful off-target genomic changes. Epigenome Editing with CRISPR.

DNA 52
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Discovery of MicroRNA Genetic Regulation Leads American Scientists to Win 2024 Nobel Prize

XTalks

Essentially, microRNAs block the expression of the gene by stopping the production of the corresponding protein from mRNA’s instructions, effectively regulating which genes are “turned on” or “off” in the cell. Their ability to modulate gene expression at the RNA level provides a novel therapeutic approach for conditions.