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FogPharma clears another big-ticket financing for its ‘miniprotein’ pipeline

pharmaphorum

The Helicons are taken into cells using endocytic trafficking, a process which sees the compounds packaged into folds in the plasma membrane, forming vesicles that are then internalised.

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Mirikizumab Up-Regulates Genes Associated with Mucosal Healing in Ulcerative Colitis for Up to One Year in Phase 2 Study

The Pharma Data

Eli Lilly and Company (NYSE: LLY) announced new Phase 2 data showing that gene expression changes induced by mirikizumab in patients with ulcerative colitis (UC) over a 12-week induction treatment were maintained for up to one year. For methodology, see the “About the Studies” section below.

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AI-designed protein awakens silenced genes, one by one

The Pharma Data

The new technique controls gene activity without altering the DNA sequence of the genome by targeting chemical modifications that help package genes in our chromosomes and regulate their activity. These methyl groups must be refreshed so if PRC2 is blocked the genes it has silenced. it can be reawakened.

Protein 52
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Women in Science Who Have Paved the Way Forward in Genetics

XTalks

Daly’s histone research proved to be pioneering, being fundamental to our understanding of DNA packaging, gene expression and epigenetics, among other areas in genetic research. She also established a scholarship fund at Queens College for African Americans in commemoration of her father in 1988.

Genetics 119