BioPharma Reporter

JULY 11, 2023

A new genetic sequencing technology from Element Biosciences has helped researchers from the Translational Genomics Research Institute (TGen), part of the City of Hope, identify the likely genetic causes of disorders in six of nine children from Sonora, Mexico.

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Gene Sequencing Gene Genetics Genome 63

BioTech 365

MAY 5, 2021

First of its kind SARS-CoV-2 detection by partial N gene sequencing now publicly available at CLIA Certified Milford Connecticut laboratory First of its kind SARS-CoV-2 detection by partial N gene sequencing now publicly available at CLIA Certified Milford Connecticut laboratory … Continue reading →

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Gene Sequencing Gene 52

BioSpace

OCTOBER 11, 2023

The European Union is expected to order the gene sequencing giant to divest Grail in the coming days, according to multiple media reports citing unnamed sources familiar with the matter.

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Gene Sequencing Gene 97

BioSpace

AUGUST 24, 2021

The development of COVID-19 vaccines, which took only months from the initial gene sequencing to the time shots were in arms, was the biggest story of 2020 alongside the pandemic itself.

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Gene Sequencing Gene Vaccination Vaccine 91

Medical Xpress

FEBRUARY 1, 2023

Next-generation cancer strategies rely on next-generation gene sequencing (NGS), which paves the way for new techniques and tools to detect mutations and determine patient therapy.

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Gene Sequencing Gene Research Genetics 61

BioTech 365

DECEMBER 3, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Research team develops software that cuts time, cost from gene sequencing.A team of Johns Hopkins University researchers has developed a new software that could revolutionize how DNA … Continue reading →

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Gene Sequencing Gene Development Research 40

Scienmag

JULY 6, 2021

New method yields 10 times more data, reduces gene sequencing costs by one third Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells.

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Gene Sequencing Gene Development Research 75

Scienmag

MAY 4, 2021

Credit: Elizabeth Cooke Next-generation gene sequencing (NGS) technologies –in which millions of DNA molecules are simultaneously but individually analyzed– theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream.

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Gene Sequencing Gene Research DNA 64

Scienmag

JUNE 1, 2022

New research led by scientists at the Milner Centre for Evolution at the University of Bath suggests that determining evolutionary trees of organisms by comparing anatomy rather than gene sequences is misleading.

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Gene Sequencing Gene Scientist Research 54

BioTech 365

APRIL 20, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Algorithm maps gene expression in space.As we accumulate more and more gene-sequencing information, cell-type databases are growing in both size and complexity.

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Gene Expression Gene Gene Sequencing Research 40

BioTech 365

FEBRUARY 4, 2021

GenapSys), the company behind the world’s first highly accurate, affordable, and accessible gene sequencer, today announced it has named Jason Myers as its Chief Executive … Continue reading → GenapSys Names Jason Myers CEO GenapSys Names Jason Myers CEO REDWOOD CITY, Calif.–(BUSINESS

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Gene Sequencing Gene 40

pharmaphorum

JUNE 23, 2022

Systemic administration of gene-editing drugs would avoid that process with an “off-the-shelf” option for a one-shot, potentially curative treatment for diseases associated with genetic mutations.

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Gene Editing In-Vivo Gene Sequencing Gene 97

XTalks

DECEMBER 14, 2022

The objective of Abudayyeh and Gootenberg’s research was to develop a gene editing tool that can facilitate the splicing and replacement of a defective gene sequence without double-stranded breaks in DNA. The researchers reported very few unwanted deletions or insertions at the sites of gene integration.

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Gene Editing DNA Gene Gene Sequencing 92

pharmaphorum

FEBRUARY 23, 2022

Interest in non-viral methods of delivering gene therapies has been growing in the face of current scrutiny of the safety of viral vectors like adeno-associated viruses (AAV), with a number of clinical programmes based on AAV under clinical holds imposed by the FDA.

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Gene Therapy Gene Gene Sequencing Immune Response 105

pharmaphorum

DECEMBER 14, 2022

The two partners have revealed the first clinical data from a phase 2b trial of a personalised vaccine consisting of 34 mRNAs, each targeting mutations – identified by gene sequencing – that are thought to be driving a patient’s cancer.

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Vaccination Vaccine Trials Gene Sequencing 98

pharmaphorum

JANUARY 5, 2023

The data was from their phase 2b trial of a personalised vaccine consisting of 34 mRNAs, each targeting mutations – identified by gene sequencing – thought to be driving a patient’s cancer. The post Boost for mRNA as Moderna to acquire OriCiro for $85 million appeared first on.

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Gene Sequencing DNA Vaccination Vaccine 97

Roots Analysis

FEBRUARY 21, 2022

Since the introduction of a gene sequencing method by Frederick Sanger in 1977, the field of genomic data collection and analysis has evolved significantly. Advancement in DNA sequencing technologies have resulted in noteworthy developments in various healthcare-related research fields, such as diagnostics and personalized medicine.

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Marketing Gene Sequencing DNA Genome 52

pharmaphorum

MARCH 10, 2022

Scenic’s platform technology Cell-Seq is used to seek out genetic modifiers, defined as gene sequences that counteract the effect of another disease-associated gene.

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Genetics Gene Sequencing Gene Clinical Trials 98

pharmaphorum

AUGUST 10, 2021

The three-year project – led by respiratory medicine expert Dr Timothy Hinks from the Oxford University Respiratory Medicine Unit – will use whole-genome sequencing of around 500 patients with severe asthma, comparing their gene sequences with control subjects who don’t have asthma.

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Gene Sequencing Bioinformatics Gene Genomics 116

pharmaphorum

OCTOBER 12, 2022

The neoantigens are selected based on gene sequencing of either a tumour biopsy or a blood sample, with an individual vaccine tailored to the patient manufactured and administered in a matter of weeks.

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Vaccination Vaccine Gene Sequencing RNA 105

pharmaphorum

SEPTEMBER 14, 2022

Meanwhile, a third gene therapy candidate – SPVN30, which combines the gene sequences in SPVN06 and SPVN20 – is in early development for RP. The post SparingVision raises €75m for eye disease gene therapies appeared first on.

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Gene Therapy Gene Gene Sequencing Gene Editing 52

pharmaphorum

MARCH 15, 2022

Gene sequencing specialist Illumina has started rolling out a new test that looks for a battery of tumour-associated genes from a single tissue sample, and could be used to help guide treatment for a broad range of cancers.

Gene 52

Gene Genome Genomics Gene Sequencing 52

pharmaphorum

AUGUST 10, 2021

The decision was taken by the UUS regulator after a case of a rare blood cancer (myelodysplastic syndrome) was seen in a patient treated with Skysona that probably arose as a result of the lentiviral vector used to deliver the gene therapy.

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Gene Therapy Gene Marketing Genetic Disease 135

pharmaphorum

AUGUST 21, 2020

Cambridge, UK-based Biofidelity has raised $12 million in first-round funding for its cancer diagnosis platform, which can detect mutations quicker than current approaches like gene sequencing.

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DNA Gene Sequencing Genetics FDA Approval 59

pharmaphorum

APRIL 23, 2021

The alliance is based on Obsidian’s cytoDRIVE platform, which uses already approved small-molecule drugs alongside gene-editing medicines to control the expression of protein from a gene sequence. For example, adding a small-molecule might stabilise the medicine, allowing levels of the target protein to increase.

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Gene Editing Genetics Drugs Gene 52

pharmaphorum

FEBRUARY 22, 2021

That therapy uses an adeno-associated virus (AAV) as a vector rather than a lentivirus, a vector type that features in approved gene therapies such as Roche’s Luxturna and Novartis’ Zolgensma. million in Europe.

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Gene Therapy Gene Gene Sequencing Gene Expression 52

FDA Law Blog

OCTOBER 24, 2024

Rather, developers of diagnostic tests and, indeed of any product that relies on free access to gene sequence and other biomarker information, should pay also close attention, as PERA would overturn longstanding judicial precedent. The concerns raised by PERA are not limited to these industries, however.

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Gene DNA Genetics Gene Sequencing 62

Roots Analysis

OCTOBER 16, 2023

DNA and Gene Cloning involves the isolation of a DNA sequence of any species ( often a gene ) and its insertion into a vector to enable growth without any alteration in the original DNA sequence. These clones can be manipulated and mutated in vitro to alter the expression and function of a protein.

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DNA Gene Protein In-Vitro 40

Roots Analysis

FEBRUARY 23, 2022

Over the past few years, several companies have started offering a diverse range of genome sequencing products and services using various second and third generation sequencing technologies.

Genetics 52

Genetics DNA RNA Reagent 52

pharmaphorum

OCTOBER 1, 2021

Shares in DNA sequencing specialist Oxford Nanopore rocketed after the company made its debut on the London Stock Exchange yesterday, rising nearly 50% to propel its valuation up towards the £5 billion ($6.7 billion) mark.

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Marketing Genomics Genome Business Development 52

The Pharma Data

DECEMBER 28, 2020

Combining next generation sequencing (“NGS”) with its technology platform, the Company performs full-gene sequencing with deletion/duplication analysis in an array of panels that can be tailored to meet specific customer needs.

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Genetics Sales Gene Sequencing Marketing 52

pharmaphorum

MAY 18, 2021

The advantage of plant-based production is that it is quick – Medicago says it produced the main ingredient for its vaccine just 20 days after the gene sequence of SARS-CoV-2 was published – and is easily scalable simply by cultivating additional plants.

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Vaccination Vaccine Immune Response Gene Sequencing 64

Pharmaceutical Technology

MAY 26, 2023

As per the company, dbDNA is suitable for rapid, scalable manufacture of GMP DNA and can incorporate gene sequences of sizes ranging from 500bp to 20kb, which are typically unstable as pDNA.

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DNA Manufacturing Gene Gene Therapy 130

pharmaphorum

FEBRUARY 19, 2021

“Since 2020 there has been a 50% increase in sequences produced in African countries. This is a priority area for us to ensure that all African countries are equipped to carry out gene sequencing locally or can send samples to reference laboratories.”. Novavax has also signed a deal to provide 1.1

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Vaccination Vaccine Gene Sequencing Manufacturing 64