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Novo Nordisk’s gene silencing alliance with Dicerna bears first fruit

pharmaphorum

Two years after starting to work together, Novo Nordisk and Dicerna have selected the first candidate from a joint project to find new, gene-silencing drugs for liver-related cardiometabolic diseases. The post Novo Nordisk’s gene silencing alliance with Dicerna bears first fruit appeared first on.

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The 3rd Annual RNAi – Based Therapeutics Summit Returns!

pharmaphorum

As the industry continues to expand RNAi drug development, it is becoming more important than ever to overcome the hurdles of analytics, raw material supply, & manufacturing. Effective Strategies to Advance Analytical Development & CMC of siRNA Therapeutics. Hear expert insights from AstraZeneca & Abbvie.

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NICE backs NHS use of Novartis’ cholesterol drug Leqvio

pharmaphorum

As well as the access agreement for high-risk patients, the Novartis deal also covers a large-scale trial of the PCSK9 inhibitor and the creation of a consortium with academic groups aimed at improving the manufacturing of oligonucleotide drugs in the UK.

Drugs 98
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RNA Therapeutics: A Novel Approach to Treating Diseases

Roots Analysis

RNA interference (RNAi) Therapeutics : Fundamentally, RNAi is a natural process of post-transcriptional gene silencing, involving short strands of nucleic acids. Cells use this process to silence and / or inhibit gene expression, via targeted degradation of specific (unwanted) mRNA molecules.

RNA 40
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FDA Approves Oxlumo (lumasiran) for the Treatment of Primary Hyperoxaluria Type 1

The Pharma Data

About RNAi RNAi (RNA interference) is a natural cellular process of gene silencing that represents one of the most promising and rapidly advancing frontiers in biology and drug development today. Until today, there were no approved pharmaceutical therapies for PH1.