Scienmag

MARCH 11, 2021

The CRISPR-based gene editor, C-to-G Base Editor (CGBE), opens up treatment avenues for up to 40 per cent of genetic disorders caused by single-nucleotide mutations Credit: Agency for Science, Technology and Research (A*STAR), Genome Institute of Singapore (GIS) A team of researchers from the Agency for Science, Technology and Research’s (A*STAR) (..)

Gene 74

Gene Scientist Genomics Genome 74

Scienmag

OCTOBER 7, 2020

Credit: UC Berkeley Biochemist Jennifer Doudna, a professor at UC Berkeley and faculty scientist at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab), is co-winner of the 2020 Nobel Prize in Chemistry for “the development of a method for genome editing.”

Genomics 89

Genomics Genome Scientist Development 89

XTalks

DECEMBER 14, 2022

We wanted to work toward what gene therapy was supposed to do at its original inception, which is to replace genes, not just correct individual mutations.”. The PASTE gene editing technique was recently published in Nature Biotechnology.

Gene Editing 98

Gene Editing DNA Gene Gene Sequencing 98

pharmaphorum

JANUARY 24, 2023

Though instances of this kind of therapy are rare, it is a growing area. The cost of testing per human genome in 2006 was approximately $14 million , and in less than two decades, an average consumer-purchased genetic test costs $100. Scientists are able to study the aggregated, de-identified genetics of these individuals.

Genetics 98

Genetics Drugs Genome Project Biobanking 98

pharmaphorum

MAY 18, 2022

Genomics has unlocked entirely new insights to what exactly may cause certain neurological conditions. Also, there is particular emphasis on exploring the potential of gene therapy to develop targeted treatments for these and further neurodegenerative conditions. Conclusion.

Gene Therapy 92

Gene Therapy Gene Genetics Development 92

Pharmaceutical Technology

FEBRUARY 3, 2023

The field of genomic medicine has reached a true turning point. With scientists fervently developing mRNA vaccines, nucleic acid therapeutics, and viral vector-based gene therapies, clinicians are set to have a growing number of tools available to treat a wide range of conditions, from infectious diseases to genetic disorders and more.

Genomics 244

Genomics Genome Medicine Gene Therapy 244

XTalks

MAY 4, 2021

The epigenome plays a key role in many diseases such as heart disease, viral infections and cancer, and the new CRISPRoff technology could lead to powerful epigenetic therapies. In the paper, the scientists also describe the CRISPRon “antidote,” which removes methylation marks placed by CRISPRoff, making the process fully reversible.

DNA 98

DNA Gene Gene Silencing Genomics 98

STAT News

FEBRUARY 22, 2023

Life Edit is the North Carolina subsidiary of ElevateBio, a cell and gene therapy manufacturing firm in Waltham. Moderna will fund preclinical research studies run by the two companies using Life Edit’s tools based on CRISPR technologies that allow scientists to make precise changes to the human genome.

Gene Editing 126

Gene Editing Gene Genetic Disease Research 126

Delveinsight

DECEMBER 15, 2020

The combined entity will put forward two rapidly converging, patient-centric models of care delivery with combined strengths in immunology, biologics, genomics and oligonucleotides to drive future medicine innovation. Welcome the new entrant in Gene therapy market: InnoSkel.

Vaccine 54

Vaccine Vaccination Gene Therapy Gene 54

XTalks

MAY 4, 2021

The epigenome plays a key role in many diseases such as heart disease, viral infections and cancer, and the new CRISPRoff technology could lead to powerful epigenetic therapies. In the paper, the scientists also describe the CRISPRon “antidote,” which removes methylation marks placed by CRISPRoff, making the process fully reversible.

DNA 52

DNA Gene Gene Silencing Genomics 52

The Pharma Data

MARCH 16, 2022

The research scientist at the Max Planck Institute for Medical Research received the award in recognition of his ground-breaking work in establishing various approaches to protein labeling in living cells that have enabled far-reaching advances in chemical and cell biology. Dr. Connor W.

Protein 52

Protein Scientist Gene Development 52

XTalks

MARCH 8, 2022

From leading COVID-19 vaccine developments to being at the helm of the latest gene therapies and inventing ground-breaking DNA technologies like CRISPR, women have been at the forefront of some of the most leading-edge scientific discoveries in recent years, both as innovators and leaders.

Life Science 105

Life Science Gene Therapy DNA Vaccine 105

The Pharma Data

AUGUST 11, 2020

In the field of immune cell therapy, this includes registrational CAR T cell agents for numerous diseases, and a growing early-stage pipeline that expands cell and gene therapy targets, and technologies. 1%) as determined by an FDA-approved test, with no EGFR or ALK genomic tumor aberrations.

Trials 52

Trials Hormones Clinical Trials Clinical Trials 52

The Pharma Data

AUGUST 11, 2020

In the field of immune cell therapy, this includes registrational CAR T cell agents for numerous diseases, and a growing early-stage pipeline that expands cell and gene therapy targets, and technologies. 1%) as determined by an FDA-approved test, with no EGFR or ALK genomic tumor aberrations.

Trials 52

Trials Hormones Clinical Trials Clinical Trials 52

Pharmaceutical Technology

FEBRUARY 20, 2023

This may lead to therapies and dosing regimes being less suitable for minority populations – and according to Hans Bunschoten, chief strategy officer at clinical research company Cerba Research, part of Cerba Healthcare, this is a major problem. The technology platforms are almost the same.

Research 130

Research Clinical Trials Clinical Trials Trials 130

Advarra

OCTOBER 10, 2024

Phages deliver their genetic material into the bacteria so, when the bacteria flourishes and reproduces, the bacteria also copies the viral genome and hands it down to bacterial progeny. As scientists look for new strategies to combat antibiotic resistance, the idea of taking advantage of bacteria’s natural pathogens has become resurgent.

Bacteria 52

Bacteria Genetics Genetic Engineering Gene 52

pharmaphorum

SEPTEMBER 1, 2020

But it was only in collaboration with the scientists at Eli Lilly that they were able to sufficiently purify the extract and industrially produce and distribute it as an effective medicine. The first was insulin – Frederick Banting and colleagues managed to isolate insulin that could treat diabetes, up until that point a fatal condition.

Medicine 145

Medicine Insulin Drugs Pharmacy 145

XTalks

DECEMBER 24, 2020

From isolating SARS-CoV-2 in early January to sequencing its genome shortly thereafter and having a prototype vaccine against it within days, scientific process and progress have held steadfast throughout the pandemic. Infectious disease expert, epidemiologist and director of the Yale Institute for Global Health at Yale University, Saad B.

Life Science 111

Life Science Vaccine Vaccination Gene 111