Scienmag

AUGUST 12, 2020

12) — Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the condition’s genetic foundations. The findings suggest that genetic analysis could be used to counsel parents who have previously experienced stillbirth and to unlock new human biology.

Genetics 40

Genetics Genetic Analysis Gene Research 40

The Pharma Data

JANUARY 7, 2021

The study — described as the most diverse genetic analysis for prostate cancer ever — included men of African, Asian, Hispanic and European ancestry. That is evidence that genetics play some role in the differences in frequency of prostate cancer among various racial groups, the study authors said.

Gene 52

Gene Genetics Genomics Genome 52

pharmaphorum

APRIL 5, 2022

Genetic analysis of tumours can reveal mutations that are fuelling cancers growth, some of which can be targeted with treatment, they note. They then used the AI to predict sensitivity to drug combinations, using 21 different two-drug combinations in lung cancer cells with different gene faults, such as mutations in EGFR and KRAS.

Protein 67

Protein Genomics Genome Genetic Analysis 67

The Pharma Data

SEPTEMBER 3, 2020

Comparing four separate forms of the disease, they found that samples of the most aggressive form, known as metastases-like primary tumours, saw changes in activity of 74 immune-related genes, compared with changes in only 12 in the more benign insulinoma-like tumours.

Research 52

Research Genetic Analysis Gene Scientist 52

Scienmag

FEBRUARY 11, 2021

A new largescale genetic analysis has found biological mechanisms that contribute to making people more susceptible to muscle weakness in later life, finding that diseases such as osteoarthritis and diabetes may play a large role in susceptibility.

Genetic Analysis 40

Genetic Analysis Genetics Research Gene 40

XTalks

MARCH 7, 2024

The company’s ResolveOME multiomic workflow provides a comprehensive multiomic analysis of breast cancer through the use of exome hybrid capture alongside a single-cell workflow for single-cell resolution of single nucleotide variants (SNVs), copy number alterations and gene expression signatures, coupled with a targeted protein panel.

Genetics 115

Genetics Hormones Genome Genomics 115

pharmaphorum

NOVEMBER 16, 2022

“The risk profile of developing AMD has been studied for years,” he said, “and more than 50% of a given individual’s risk profile is dependent on their genetics. So, pegcetacoplan blocks an inflammatory pathway that appears to be central for geopathic genesis based on extensive genetic analysis,” Dr Wykoff concluded.

Genetics 105

Genetics Trials Clinical Trials Clinical Trials 105

Delveinsight

FEBRUARY 25, 2021

Beam Therapeutics has taken over a startup whose technology could proffer the biotech’s genetic medicines to more tissues in the body, widening the potential to approach more diseases. The gene-editing technologies, which have reached the clinic, CRISPR, zinc finger nucleases, and TALENs, make their edits by nicking DNA at the target site.

DNA 52

DNA In-Vivo Genetics Medicine 52

The Pharma Data

APRIL 8, 2022

Genetic analysis revealed that the mechanical strain had activated molecular pathways related to immune defense and multiple antiviral genes, and these activations were reversed when the cyclical stretching was stopped.

Immune Response 52

Immune Response In-Vivo Genetic Analysis Research 52