FDA Law Blog

MARCH 13, 2023

This meeting will host a panel of rare disease patients, caregivers, and advocates to have a focused discussion on the emerging field of gene therapy (regulated at the FDA by OTP). At least some (if not all) of the panelists will have had experience participating in gene therapy trials. One family’s daughter was the first U.S.

Gene Therapy 98

Gene Therapy Gene Trials Clinical Trials 98

The Pharma Data

JANUARY 7, 2021

Now, research is helping to bring genetic risks for people of various racial and ethnic groups into focus. Researchers from the USC Center for Genetic Epidemiology in Los Angeles and the Institute of Cancer Research in London led the study. THURSDAY, Jan. Men of Asian ancestry inherit about three-quarters the risk of white men.

Gene 52

Gene Genetics Genome Genomics 52

Scienmag

FEBRUARY 11, 2021

A new largescale genetic analysis has found biological mechanisms that contribute to making people more susceptible to muscle weakness in later life, finding that diseases such as osteoarthritis and diabetes may play a large role in susceptibility.

Genetic Analysis 40

Genetic Analysis Genetics Research Gene 40

XTalks

MARCH 7, 2024

Breast Cancer Multiomics: Unified Insights in Tumor Heterogeneity This on-demand webinar introduces a cutting-edge single-cell multiomics method designed for garnering detailed genetic insights into breast cancer. The test accurately identified a range of genetic abnormalities, including trisomies and microdeletions.

Genetics 113

Genetics Hormones Genome Genomics 113

pharmaphorum

APRIL 5, 2022

Genetic analysis of tumours can reveal mutations that are fuelling cancers growth, some of which can be targeted with treatment, they note. They then used the AI to predict sensitivity to drug combinations, using 21 different two-drug combinations in lung cancer cells with different gene faults, such as mutations in EGFR and KRAS.

Protein 67

Protein Genome Genomics Genetic Analysis 67

The Pharma Data

SEPTEMBER 3, 2020

Comparing four separate forms of the disease, they found that samples of the most aggressive form, known as metastases-like primary tumours, saw changes in activity of 74 immune-related genes, compared with changes in only 12 in the more benign insulinoma-like tumours.

Research 52

Research Genetic Analysis Gene Scientist 52

Delveinsight

FEBRUARY 25, 2021

Beam Therapeutics has taken over a startup whose technology could proffer the biotech’s genetic medicines to more tissues in the body, widening the potential to approach more diseases. The gene-editing technologies, which have reached the clinic, CRISPR, zinc finger nucleases, and TALENs, make their edits by nicking DNA at the target site.

DNA 52

DNA In-Vivo Genetics Medicine 52

pharmaphorum

NOVEMBER 16, 2022

“The risk profile of developing AMD has been studied for years,” he said, “and more than 50% of a given individual’s risk profile is dependent on their genetics. So, pegcetacoplan blocks an inflammatory pathway that appears to be central for geopathic genesis based on extensive genetic analysis,” Dr Wykoff concluded.

Genetics 105

Genetics Trials Clinical Trials Clinical Trials 105

The Pharma Data

APRIL 8, 2022

Genetic analysis revealed that the mechanical strain had activated molecular pathways related to immune defense and multiple antiviral genes, and these activations were reversed when the cyclical stretching was stopped.

Immune Response 52

Immune Response In-Vivo Genetic Analysis Research 52