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World Cancer Day 2024: Trends in Oncology Research and More

XTalks

Innovations in Cancer Therapy CRISPR/Cas9, a groundbreaking gene-editing technology, has demonstrated significant potential in oncology, offering new avenues for cancer treatment. By editing these genes, researchers can effectively neutralize their cancer-promoting effects.

Research 118
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How Advanced Diagnostics are Shaping the Future of Precision Medicine and Gene Therapy

Cloudbyz

This revolution is enabling the growth of innovative biomarker-based precision medicine and cell and gene therapy, transforming both clinical research and post-market care. For instance, in oncology, patients with specific genetic mutations (e.g.,

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Patient Safety and Radiopharmaceuticals Administration: Minimizing Radiation Exposure and Risks

Worldwide Clinical Trials

Genetic Factors : Certain genetic mutations, such as those in DNA repair genes, can affect how cells respond to radiation. Individuals with familial cancer syndrome may have inherited mutations that predispose them to cancer development, affecting genes involved in DNA repair and cell cycle regulation.

Hormones 130
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Considerations for Neuroscience Trials with Intrathecal Delivery and Other Methods of Direct CNS Administration

XTalks

We know that a lot of different pathologies, especially as we’ve entered the era of molecular medicine and gene therapies, cause many of the same symptoms and work through final common pathways. Viral Vectors for Gene Delivery to the CNS. Reporter genes to understand dose and distribution. The patients are waiting!

Trials 83
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Hypoxia-Inducible Factor-2 Alpha (HIF-2?) Inhibitor WELIREG™ (belzutifan) for the Treatment of Patients With Certain Types of Von Hippel-Lindau (VHL) Disease-Associated Tumors

The Pharma Data

target genes associated with cellular proliferation, angiogenesis and tumor growth. The major efficacy endpoint for the treatment of VHL-associated RCC was ORR measured by radiology assessment using RECIST v1.1 This is a rare genetic disease with an estimated incidence of 10,000 people in the U.S. WELIREG is the first HIF-2?

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The Utility of Liquid Biopsy in Oncology Clinical Trials

XTalks

Such information can reveal details about tumor staging, tumor progression, heterogeneity, gene mutations and clonal evolution. Dr. Bahassi explained that technological advances in genetic sequencing of cfDNA have enabled liquid biopsies and led to marked increase in the detection of therapeutically-targetable mutations.

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AstraZeneca’s COVID-19 vaccine; Type 1 diabetes research updates; FDA nod to Zebra’s X-ray modelling AI; UniQure/CSL haemophilia B gene therapy curbs bleeding in phase 3

Delveinsight

Mice that were genetically modified to be in a deficit of the protein were secured from Type 1 diabetes, and a small peptide inhibitor of OCA-B also prevented the disease in newly diabetic animals, as per the results published in the Journal of Experimental Medicine. UniQure/CSL haemophilia B gene therapy curbs bleeding in phase 3.