Scienmag

DECEMBER 23, 2020

Forward genetics pinpoints gene linked to ASD involving severe speech impairment and opens door to search for more mutations, future treatments Credit: Photo taken by Brian Coats for UT Southwestern Medical Center DALLAS – Dec.

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Scientist Gene Genetics Research 97

STAT News

NOVEMBER 30, 2022

The scientists sent the blood 950 miles east to Massachusetts General Hospital in Boston, to a tiny lab (recently converted from a storeroom) where a 28-year-old postdoc named James Gusella and his 23-year-old research technician, Rudolph Tanzi, got to work.

Genetics 111

Genetics Scientist DNA Gene 111

Worldwide Clinical Trials

DECEMBER 12, 2022

Genetic testing provides patients with a diagnosis for their illness, helps patients and family members to understand risks of developing new diseases, and can be used to support clinical trial advancement. What are the benefits and limitations to using genetic testing? It is important to consider the type of testing performed (e.g.,

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Clinical Trials Clinical Trials Genetics Trials 130

Pharmaceutical Technology

JULY 7, 2022

Genetic mutations, both germline and acquired, are behind a large proportion of the most debilitating and sometimes life-threatening human diseases. But scientists have struggled to find effective treatments for many of these diseases since the dawn of modern medicine. A new frontier in cancer research.

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Gene Therapy Gene Medicine Genetics 245

Medical Xpress

MARCH 2, 2023

QUT and Dutch scientists have identified two new genes involved in hemiplegic migraine, a rare, debilitating subtype of migraine that causes weakness along one side of the body during the aura phase.

Scientist 76

Scientist Gene Genetics 76

BioSpace

JULY 14, 2021

The next COVID pandemic could be prevented by using a gene drive to preemptively edit the genome of bats to prevent them from becoming hosts for coronaviruses, according to a proposal by scientists from Israel’s Interdisciplinary Center Herzelia and the National Institutes of Health.

Scientist 99

Scientist Genetics Genome Genomics 99

STAT News

FEBRUARY 22, 2023

Moderna is aiming to build a gene editing franchise powered by some of the same technologies used in its COVID-19 vaccines. The Cambridge biotech company announced Wednesday that it will partner with Life Edit Therapeutics to develop potentially permanent treatments for rare genetic diseases and other conditions.

Gene Editing 126

Gene Editing Gene Genetic Disease Research 126

Scienmag

APRIL 8, 2021

Credit: UT Southwestern Medical Center DALLAS – April 8, 2021 – New research has uncovered a surprising role for so-called “jumping” genes that are a source of genetic mutations responsible for a number of human diseases.

Scientist 77

Scientist Gene Genetics Research 77

Scienmag

OCTOBER 13, 2021

LA JOLLA—(October 13, 2021) For the past fifteen years, cancer researchers have been using DNA sequencing technology to identify the gene mutations that cause the different forms of cancer.

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Scientist Gene DNA Genetics 52

Medical Xpress

MAY 15, 2023

Scientists at Université de Montréal, McGill University and its affiliated Montreal Children's Hospital have made a promising breakthrough in understanding the origins of mirror movement disorder, a rare inherited neurological disorder.

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Scientist Gene Genetics 98

Scienmag

MARCH 5, 2021

Researchers develop tunable system that harnesses the spread of cargo carried by gene drives Credit: Gerard Terradas, UC San Diego Powerful new genetic engineering methods have given scientists the potential to revolutionize several sectors of global urgency.

Gene 52

Gene Scientist Genetic Engineering Genetics 52

BioTech 365

OCTOBER 26, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists develop genetic ‘monitors’ that detect when genes are active.Genetic sensors that can detect the activity from genes, rather than just the genes themselves, have been developed … Continue reading → (..)

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Genetics Gene Scientist Development 40

Scienmag

MAY 31, 2021

NIH- and USU- led study links ALS to a fat manufacturing gene and maps out a genetic therapy Credit: Courtesy of the NIH/NINDS.

Genetics 56

Genetics Scientist Gene Manufacturing 56

Medical Xpress

MAY 4, 2023

Mutations of a gene called Foxp2 have been linked to a type of speech disorder called apraxia that makes it difficult to produce sequences of sound. A new study from MIT and National Yang Ming Chiao Tung University sheds light on how this gene controls the ability to produce speech.

Gene 98

Gene Scientist Genetics 98

Scienmag

NOVEMBER 25, 2020

Credit: Professor Jane Farrar and Dr Daniel Maloney, Trinity College Dublin Scientists from Trinity College Dublin have developed a new gene therapy approach that offers promise for one day treating an eye disease that leads to a progressive loss of vision and affects thousands of people across the globe.

Gene Therapy 87

Gene Therapy Scientist Gene Development 87

Scienmag

MAY 6, 2021

Jude Children’s Research Hospital scientists have developed a highly efficient method to address a major challenge in biology–identifying the genetic ‘switches’ that regulate gene expression. Credit: St. Jude Children’s Research Hospital St.

Gene Expression 97

Gene Expression Regulation Gene DNA 97

STAT News

FEBRUARY 7, 2023

From the color of our eyes to our odds of developing cancer, we’re all shaped by the genetic legacy of our ancestors. Both these modifications and their metabolic effects were shown to have passed down for at least three to six generations — something scientists once assumed was impossible. Read the rest…

Gene 105

Gene DNA Genetics Scientist 105

Scienmag

MARCH 31, 2021

Independent of cholesterol, gene variants raise risk of heart disease, diabetes, high blood pressure Credit: In-Hyuk Jung, PhD, Stitziel Lab High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke.

Scientist 62

Scientist Genetics Gene Medicine 62

Scienmag

JANUARY 6, 2021

Credit: IGDB Chinese scientists from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS) have found a gene that plays an important role in helping rice adapt to low soil nitrogen.

Scientist 52

Scientist Gene Genetics 52

Scienmag

JUNE 24, 2021

NIH scientists discover that bacteria may drive activity of many hallmark aging genes in flies Credit: Courtesy of the Giniger lab NIH/NINDS.

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Scientist Gene Bacteria Research 72

Scienmag

FEBRUARY 23, 2021

CRISPR gene editing has transformed research, but it is not perfect, and can sometimes target unintended genes; to watch CRISPR enzymes respond to different genes, Leipzig University researchers developed a new method using DNA origami and were able to me Credit: Image courtesy of Julene Madariaga Marcos.

DNA 56

DNA Gene Gene Editing Scientist 56

Scienmag

APRIL 16, 2021

– April 16, 2021 – Scientists at Sanford Burnham Prebys have identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes COVID-19. Credit: Dotted Yeti LA JOLLA, CALIF.

Gene 60

Gene Scientist Research Allergies 60

pharmaphorum

JANUARY 24, 2023

Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates. The logical extension to this kind of approach is treating individual patients, with their individual genetic makeup.

Genetics 98

Genetics Drugs Genome Project Biobanking 98

Scienmag

MARCH 11, 2021

The CRISPR-based gene editor, C-to-G Base Editor (CGBE), opens up treatment avenues for up to 40 per cent of genetic disorders caused by single-nucleotide mutations Credit: Agency for Science, Technology and Research (A*STAR), Genome Institute of Singapore (GIS) A team of researchers from the Agency for Science, Technology and Research’s (A*STAR) (..)

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Gene Scientist Genome Genomics 74

Scienmag

APRIL 27, 2022

CHAPEL HILL, NC – Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA – a crucial regulatory step before proteins are created. Then, organs develop and hopefully function properly.

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Scientist Gene RNA Protein 83

Scienmag

JUNE 23, 2022

Scientists have discovered some genetic variants that increase the risk for developing Alzheimer’s; the most well-known of these for people over the age of 65 is the APOE ?4 (Boston)—Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8

Genetics 62

Genetics Gene Research Scientist 62

Medical Xpress

DECEMBER 7, 2022

New research published in the Annals of Clinical and Translational Neurology has identified three genes and their expressed proteins that may be involved in the pathogenesis of multiple sclerosis.

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Gene Scientist Protein Research 75

Scienmag

MARCH 30, 2021

Credit: Gretel Nicholson, EXRC Scientists have discovered a new genetic disease, which causes some children’s brains to develop abnormally, resulting in delayed intellectual development and often early onset cataracts.

Genetic Disease 52

Genetic Disease Genetics Scientist Development 52

Scienmag

MARCH 25, 2021

Decade-long search uncovers genes responsible for lacunar strokes, a major cause of vascular dementia Scientists have identified new genetic clues in people who’ve had small and often apparently ‘silent’ strokes that are difficult to treat and a major cause of vascular dementia, according to research funded by the British Heart Foundation (..)

Genetics 75

Genetics Gene Scientist Research 75

BioTech 365

MARCH 18, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists uncover the underlying genetics that make flies champion fliers.Flies have developed excellent flying skills thanks to a set of complicated interactions between numerous genes influencing wing … Continue reading (..)

Genetics 40

Genetics Scientist Gene Development 40

Medical Xpress

NOVEMBER 16, 2022

Researchers at the National Institutes of Health have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD).

Gene 98

Gene Research Genome Genomics 98

pharmaphorum

FEBRUARY 22, 2022

A study has revealed that current NHS guidelines on testing for genetic alterations linked to cancer could be missing around half of people carrying them, says a new study. The post NHS gene testing missing half of people at cancer risk appeared first on. That corresponds to just under 5% of the total sample size. Prof Rosalind Eeles.

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Gene Genetics Scientist Research 105

Scienmag

MARCH 29, 2021

Tissue collection at NOAA Fisheries lab helps reveal genetic distinction Credit: Mansur/WCR Bangladesh New genetic analysis and years of painstaking research has revealed that one of the world’s most endangered marine mammals is actually two species rather than one, as scientists had long assumed.

Genetics 86

Genetics Genetic Analysis Scientist Research 86

Scienmag

APRIL 15, 2021

Team of Japanese and European scientists identify a novel genetic mitochondrial disorder by analyzing DNA samples from three distinct families Credit: Fujita Health University DNA ligase proteins, which facilitate the formation of bonds between separate strands of DNA, play critical roles in the replication and maintenance of DNA.

Genetics 105

Genetics DNA Genome Genomics 105

Scienmag

AUGUST 14, 2020

Finding could lead to genetic tests that identify infants at risk for the disease Credit: NIAID WHAT: New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, promoting the development (..)

Genetics 52

Genetics Scientist Gene Development 52

Scienmag

JULY 6, 2021

Credit: UT Southwestern Medical Center Using artificial intelligence, UT Southwestern scientists have identified thousands of genetic mutations likely to affect the immune system in mice. “This study identifies 101 novel gene candidates with greater than 95% chance of […].

Scientist 77

Scientist Genetics Gene Medicine 77

XTalks

DECEMBER 14, 2022

Expanding upon the CRISPR-Cas9 gene editing system, researchers at MIT have designed a new technique called PASTE gene editing that can cut out defective genes and replace them with new genes in a safer and more efficient way. The PASTE gene editing technique was recently published in Nature Biotechnology.

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Gene Editing DNA Gene Gene Sequencing 95