XTalks

AUGUST 30, 2022

We know that a lot of different pathologies, especially as we’ve entered the era of molecular medicine and gene therapies, cause many of the same symptoms and work through final common pathways. Viral Vectors for Gene Delivery to the CNS. Reporter genes to understand dose and distribution. The patients are waiting!

Trials 83

Trials Drug Delivery Drugs Gene 83

pharmaphorum

APRIL 7, 2021

Novartis has made radioligands one of four pillars of its cancer business, along with cell and gene therapy, targeted drugs and immunotherapeutics, and has been steadily bolting on assets to expand its pipeline in this area.

DNA 52

DNA Licensing Licensing Gene Therapy 52

The Pharma Data

AUGUST 5, 2021

Bayer recently formed its own cell and gene therapy platform as part of its transformation strategy for Pharmaceuticals. Research and development expenses increased against the low prior-year figure and were partly attributable to the cell and gene therapy unit. Sales of prescription medicines (Pharmaceuticals) rose by 16.2

Sales 52

Sales Production Gene Therapy Allergies 52

The Pharma Data

AUGUST 15, 2021

target genes associated with cellular proliferation, angiogenesis and tumor growth. The major efficacy endpoint for the treatment of VHL-associated RCC was ORR measured by radiology assessment using RECIST v1.1 WELIREG is the first HIF-2? inhibitor therapy approved in the U.S. As an inhibitor of HIF-2?, months (range, 2.8

Hormones 52

Hormones Clinical Trials Clinical Trials Trials 52

XTalks

NOVEMBER 7, 2022

Such information can reveal details about tumor staging, tumor progression, heterogeneity, gene mutations and clonal evolution. The first option is to design a personalized small NGS gene panel based on the somatic mutations that were detected in the patient, and this can be used for monitoring disease progression.

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

Delveinsight

DECEMBER 10, 2020

OCA-B, or B cell-specific Oct1/2 coactivator, binds to and controls about 150 genes involved in a process through which T cells are reactivated upon reencountering antigens they have earlier identified and memorised. UniQure/CSL haemophilia B gene therapy curbs bleeding in phase 3.

Gene Therapy 52

Gene Therapy Gene Vaccination Vaccine 52

The Pharma Data

DECEMBER 23, 2020

Of the 17 mutations, eight are in the gene that encodes the spike protein. Gene Pathway Linked to Schizophrenia. One of the differentially expressed genes along the pathway is serum-glucocorticoid kinase 1 (SGK1), an inhibitor of GSK3 beta, which has been linked with schizophrenia. Two are particularly concerning.

Research 52

Research Protein Gene Vaccination 52

The Pharma Data

MAY 3, 2021

Six patients with dementia went to Mexico for an unproven gene therapy, a biotech CEO claims ( STAT ). Avrobio changes course after FDA closes path for speedy gene therapy approval ( BioPharmaDive ). Radiology Partners, Aidoc talk AI adoption, handling bias, FDA actions ( MedtechDive ).

Gene Therapy 52

Gene Therapy Vaccination Vaccine Bioequivalency 52

XTalks

SEPTEMBER 14, 2020

Results are available in about 15 minutes, so the test is much faster than currently available tests which detect viral genes. Drugs and Vaccines.

Vaccination 92

Vaccination Vaccine Antibody Life Science 92