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Tryngolza works by targeting a protein in the liver, apoC-III, which regulates triglyceride metabolism. People with FCS often have triglyceride levels higher than 880 mg/dL, compared to a healthy target level of below 150 mg/dL. FCS also severely impacts quality of life, causing chronic fatigue and recurrent stomach pain.
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Not only this, the potential for this type of therapy extends far beyond infectious diseases and into numerous therapy areas. On the back of the approvals for Pfizer/BioNTech and Moderna, suddenly there is a large amount of interest from big pharmacompanies to get involved in the mRNA space. Attracting attention.
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