pharmaphorum

JANUARY 26, 2023

2022 was a banner year for genomics. In March, the collaborative T2T consortium published the first complete telomere-to-telomere sequence of the human genome, filling in the last 8% of the 3 billion base pairs that make up our DNA.

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Genomics Genome Genome Project Genetics 129

Scienmag

NOVEMBER 25, 2020

Credit: Photo: IPK Leibniz Institute/ Andreas Bähring In order to record all genetic information of an individual, its genome must be completely decoded. IPK scientists and international partners for barley already succeeded in doing this three years ago (Mascher et al.

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Genomics Genome Scientist Genetics 88

STAT News

MARCH 3, 2023

Next week, hundreds of scientists from around the world will convene in London for an international summit on genome editing. That technology, which enables scientists to easily excise, alter, or replace specific sections of DNA, was awarded the 2020 Nobel Prize for Chemistry. Continue to STAT+ to read the full story…

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Genomics Genome Gene Editing Genetic Disease 111

STAT News

FEBRUARY 16, 2023

Zhang, one of the leading scientists in the groundbreaking field of genetic editing, had reached out two days prior to discuss a new company he was working on. Akin Akinc was scouring his email spam box last summer, looking for a missing message, when he stumbled across an unexpected email from a quite recognizable name: Feng Zhang.

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Scienmag

MARCH 10, 2022

Scientists have developed a powerful, inclusive new tool for genomic research that boosts efforts to develop more precise treatments for many diseases by leveraging a better representation of the genetic diversity of people around the world.

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Genomics Genome Research Scientist 84

XTalks

APRIL 21, 2023

The application of whole genome sequencing (WGS) to derive a more complete understanding of cancer has been a central goal of cancer researchers even before the first human genome was decoded in 2003. Ultima Genomics has already partnered with other leading biotech startups.

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Genomics Genome Bioinformatics Genetics 77

Worldwide Clinical Trials

DECEMBER 12, 2022

Genetic testing provides patients with a diagnosis for their illness, helps patients and family members to understand risks of developing new diseases, and can be used to support clinical trial advancement. What are the benefits and limitations to using genetic testing? It is important to consider the type of testing performed (e.g.,

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Clinical Trials Clinical Trials Genetics Trials 130

XTalks

OCTOBER 8, 2024

The 2024 Nobel Prize in Physiology or Medicine has been awarded to American scientists Victor Ambros and Gary Ruvkun for their groundbreaking discovery of microRNA (or miRNA) and its role in post-transcriptional gene regulation. This control plays a critical role in development and cellular function.

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Regulation Genetics Scientist RNA 52

BioSpace

JULY 14, 2021

The next COVID pandemic could be prevented by using a gene drive to preemptively edit the genome of bats to prevent them from becoming hosts for coronaviruses, according to a proposal by scientists from Israel’s Interdisciplinary Center Herzelia and the National Institutes of Health.

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Scientist Genetics Genomics Genome 99

Pharmaceutical Technology

JUNE 30, 2022

Earlier this month, scientists from Cambridge University and the Madrid-based National Cancer Research Center described a novel framework tracking chromosomal instability and copy number changes in particularly deadly cancers. Genomic research have greatly expanded our understanding of disease pathophysiology over the years.

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STAT News

MARCH 6, 2023

That was the message Chinese scientists delivered Monday on the opening day of the Third International Summit on Human Genome Editing in London. LONDON — The first gene-edited children were born in China five years ago , but it’s unlikely to happen again there anytime soon.

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Genomics Genome Gene Editing Genetics 98

Scienmag

APRIL 15, 2021

Team of Japanese and European scientists identify a novel genetic mitochondrial disorder by analyzing DNA samples from three distinct families Credit: Fujita Health University DNA ligase proteins, which facilitate the formation of bonds between separate strands of DNA, play critical roles in the replication and maintenance of DNA.

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Genetics DNA Genomics Genome 105

BioTech 365

FEBRUARY 2, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: ‘Genetic SD-card’: Scientists obtain new methods to improve the genome editing system.Researchers from Peter the Great St.Petersburg Polytechnic University (SPbPU) in collaboration with colleagues from Belgium take (..)

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Genomics Genome Genetics Scientist 40

Pharmaceutical Technology

FEBRUARY 3, 2023

The field of genomic medicine has reached a true turning point. With scientists fervently developing mRNA vaccines, nucleic acid therapeutics, and viral vector-based gene therapies, clinicians are set to have a growing number of tools available to treat a wide range of conditions, from infectious diseases to genetic disorders and more.

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Genomics Genome Medicine Gene Therapy 244

Scienmag

FEBRUARY 9, 2022

A new genomic analysis by an international team of scientists has now uncovered the genetic underpinnings of some of the most unusual features of Steller’s […].

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Genomics Genome Genetics Scientist 87

pharmaphorum

JANUARY 18, 2023

In 2016, scientists behind a study called the Resilience Project analysed genetic data from 589,000+ people and found 13 adults who carried genetic variants that should have resulted in serious – even deadly – childhood disease, but who were apparently healthy. Giving participants something in return.

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Genetic Disease Genetics Research Genome 96

BioTech 365

APRIL 16, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists are on a path to sequencing 1 million human genomes and use big data to unlock genetic secrets.The first draft of the human genome was published … Continue reading →

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Medical Xpress

MARCH 27, 2023

To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.

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Genomics Genome Scientist Genetics 75

Scienmag

FEBRUARY 25, 2021

Publication in Science Credit: David Porubsky, University of Washington In 2001, the International Human Genome Sequencing Consortium announced the first draft of the human genome reference sequence. This reference, however, […].

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Genomics Genome Genome Project Genetics 60

Pharmaceutical Technology

JUNE 14, 2023

However, more immeasurable characteristics such as personality, behaviour, and even intelligence are all influenced by genetics to varying degrees. All that DNA is organised into hereditary units called genes, with humans having about 25,000 genes collectively known as the genome. The first human genome cost $2.7bn to sequence.

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Genome Project Medicine Genomics Genome 130

BioTech 365

SEPTEMBER 28, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists use ‘genomic time travel’ to discover new genetic traits to breed more productive, resilient African cattle.Scientists announced today the discovery of a new set of detailed … Continue reading → (..)

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Genomics Genome Genetics Scientist 40

pharmaphorum

JANUARY 24, 2023

Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates. The logical extension to this kind of approach is treating individual patients, with their individual genetic makeup.

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Genetics Drugs Genome Project Biobanking 97

STAT News

MARCH 1, 2023

Genome editing summits are generally friendly, nerdy affairs, but for a moment at a Lisbon hotel last June, the conversation at the FASEB genome engineering conference grew tense. ” It was a rare moment: Tessera had raised around $600 million and passed a $1 billion valuation, but published little in academic medical journals.

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Gene Editing Genetic Disease Genomics Genome 119

Medical Xpress

DECEMBER 12, 2022

For the most part, the genomic changes that underlie this metamorphosis and push it forward have been obscure, hindering advances in treatment.

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Genetics Scientist Genomics Genome 81

pharmaphorum

SEPTEMBER 14, 2020

Last week geneticist Dr Charles Steward shared with us his experiences of searching for a genetic cause for his children’s rare neurological diseases. Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential.

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Genomics Genome Medicine Gene 119

pharmaphorum

OCTOBER 19, 2022

million ($40 million) first-round financing that will be used to explore so-called ‘dark’ regions of the human genome. Nucleome’s platform adds 3D genomic information to a wealth of available genomic data, uncovering a new dimension of information that is disease as well as cell type-specific.

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Genomics Genome Gene Gene Expression 59

Scienmag

OCTOBER 13, 2021

An artificial intelligence (AI)-based technology rapidly diagnoses rare disorders in critically ill children with high accuracy, according to a report by scientists from University of Utah Health and Fabric Genomics, collaborators on a study led by Rady Children’s Hospital in San Diego.

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Genetics Genomics Genome Scientist 87

pharmaphorum

JULY 20, 2022

Now, scientists in the UK think they have found a culprit implicated in cancer. Junk DNA is a term used to describe the 97% of the genetic sequence in human cells found between the 3% coding for our 20,000 genes, once thought to be inert. The post UK scientists say they have found cancer driver in junk DNA appeared first on.

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DNA Scientist Genome Genomics 115

Scienmag

SEPTEMBER 29, 2020

Credit: Dr Ira Deveson A new mobile app has made it possible to analyse the genome of the SARS-CoV-2 virus on a smartphone in less than half an hour.

Genomics 55

Genomics Genome Genetics Scientist 55

Scienmag

NOVEMBER 25, 2020

Credit: University of Adelaide An international research collaboration, including scientists from the University of Adelaide’s Waite Research Institute, has unlocked new genetic variation in wheat and barley – a major boost for the global effort in breeding higher-yielding wheat and barley varieties.

Genomics 52

Genomics Genome Genome Project Genetics 52

XTalks

NOVEMBER 10, 2020

Expeditious and accurate diagnoses are necessary for patients to access healthcare services and treatment options for rare genetic diseases. Increasing the efficiency of case analysis and interpretation is essential to providing timely care for patients with genetic diseases.

Genomics 98

Genomics Genome Medicine Genetic Disease 98

BioTech 365

SEPTEMBER 11, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists debate promise, peril of tweaking wild genomes.In the movie Jurassic Park, reconstructing and tweaking genetic material makes it possible to bring dinosaurs back to life.

Scientist 40

Scientist Genomics Genome Genetics 40

Scienmag

DECEMBER 15, 2020

An international team of Swedish, Norwegian, Danish and Irish scientists has used whole genome sequencing to characterise 53 herring populations from the Atlantic Ocean and the Baltic Sea. They have developed genetic markers that make it possible to better monitor herring populations and avoid overfishing.

Genomics 52

Genomics Genome Genetics Scientist 52

STAT News

OCTOBER 3, 2022

A Swedish scientist won the 2022 Nobel Prize in medicine or physiology on Monday for his groundbreaking research into the evolutionary history of humankind. Pääbo unlocked scientists’ understanding of how genes from these extinct relatives have been passed down to present-day humans.

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Medicine Research Contamination DNA 142

pharmaphorum

OCTOBER 2, 2020

Swiss medical data specialist Sophia Genetics has raised $110 million in an oversubscribed funding round that will be used to boost its headcount and international presence and prepare to take its shares public. The post $110m financing sets up US, Asia expansion for Sophia Genetics appeared first on.

Genetics 59

Genetics Genome Genomics Life Science 59

Scienmag

MARCH 11, 2021

The CRISPR-based gene editor, C-to-G Base Editor (CGBE), opens up treatment avenues for up to 40 per cent of genetic disorders caused by single-nucleotide mutations Credit: Agency for Science, Technology and Research (A*STAR), Genome Institute of Singapore (GIS) A team of researchers from the Agency for Science, Technology and Research’s (A*STAR) (..)

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Gene Scientist Genomics Genome 74

Medical Xpress

FEBRUARY 10, 2023

They report their findings in npj Genomic Medicine. Researchers at the National Institutes of Health have discovered a new neurological condition characterized by issues with motor coordination and speech.

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Scientist Genomics Genome Medicine 98