XTalks

JUNE 21, 2024

The ban targets artificial smoke flavorings linked to genotoxicity concerns. Genotoxicity involves damage to genetic material within cells, increasing cancer and inherited disease risks. The EFSA concluded that the majority of assessed smoke flavorings posed genotoxicity risks. Other companies, like I.T.S

Genotoxicity 52

Genotoxicity Regulation Production Manufacturing 52

Drug Discovery World

JANUARY 10, 2024

These therapies, which exhibit substantial long-term side effects, including genotoxicity and an increased predisposition to secondary cancers, have significantly higher rates of subsequent malignancies than the rate reported for patients following CAR-T cell immunotherapies.

Gene Therapy 59

Gene Therapy Genotoxicity Gene Genetics 59

Drug Discovery World

MAY 10, 2023

This stage is more highly regulated and consists of both preclinical testing and clinical trials. Specific guidelines set forth to regulate these testing processes are issued by the ICH, a non-profit organisation with representation from global regulatory agencies and pharmaceutical companies. Toxicologic Pathology. 2011;39(4):716-744.

Bioassay 52

Bioassay Genotoxicity Drugs In-Vivo 52

The Pharma Data

MAY 13, 2021

The trans-fat ban–food regulation and long-term health. Exposure to sorbitol during lactation causes metabolic alterations and genotoxic effects in rat offspring. Regulation of glucose metabolism from a liver-centric perspective. Neural and Genetic Correlates of the Social Sharing of Happiness. Biochem Cell Biol.

Insulin 52

Insulin Production Hormones Medicine 52