Scienmag

APRIL 19, 2022

New Edith Cowan University (ECU) research has identified a crucial link between arthritis and the risk of serious liver disease in people with Australia’s most common genetic condition.

Genetics 62

Genetics Genotype Research 62

Worldwide Clinical Trials

AUGUST 14, 2024

Historically, these indications have challenged the one-size-fits-all treatment approach due to patient variability, such as genetic differences in drug metabolism and underlying health conditions. This resistance may occur due to genetic mutations, epigenetic changes, or a tumor’s microenvironment.

Genetics 195

Genetics Protein Gene Genotype 195

pharmaphorum

OCTOBER 9, 2020

The rare, X-linked genetic condition is characterised by short stature and facial, limb and genital abnormalities and was first described in 1970. Because Aarskog is an X-linked genetic condition affecting predominantly males, women have traditionally been considered asymptomatic carriers. No one would listen.”.

Research 111

Research Genetics Genotype Nurses 111

Scienmag

JANUARY 13, 2021

Credit: Delaneau Group Thousands of genetic markers have already been robustly associated with complex human traits, such as Alzheimer’s disease, cancer, obesity, or height.

Genome 57

Genome Genomics Genotype Genetics 57

XTalks

FEBRUARY 4, 2021

Generation of strong research dataset cohorts must begin with high-quality clinical samples. Moreover, biobanks are no longer passive biorepositories for accrual of samples and serve a more utilitarian function in identifying and coordinating specific research cohorts for longitudinal and prospective studies.

Research 98

Research Biobanking Drugs Genomics 98

Scienmag

AUGUST 25, 2020

Credit: Iliana Baums, Penn State Coral conservation efforts could get a boost from a newly developed genotyping “chip”–the first of its kind for corals.

Genotype 66

Genotype Genetics Development Research 66

The Pharma Data

NOVEMBER 18, 2020

Genetics Tied to Thromboembolism Risk With Inflammatory Bowel Disease. 18, 2020 — Genetic variants in some patients with inflammatory bowel disease (IBD) are associated with a significantly increased risk for developing thromboembolic disease (TED), according to a study published online Oct. Professional. WEDNESDAY, Nov.

Genetics 52

Genetics Genotype Genomics Genome 52

pharmaphorum

JANUARY 16, 2023

Hormone replacement therapy (HRT) could cut the risk of Alzheimer’s in some women at elevated risk of the disease, according to researchers in the UK. Their work specifically focused on the effect of HRT on women with the APOE4 genotype. The research is published in the journal Alzheimer’s Research and Therapy.

Hormones 75

Hormones Genotype Research Genetics 75

XTalks

JANUARY 21, 2025

There, plasma is separated, and tumor DNA is identified by detecting genetic mutations, methylation patterns and fragmentation signals. Using cervical or self-collected vaginal specimens, the test works with the BD Viper LT and BD COR systems to detect individual genotypes, such as HPV 16, 18 and 31, and grouped results for other types.

FDA Approval 105

FDA Approval Manufacturing Development RNA 105

XTalks

SEPTEMBER 28, 2020

Based on the genetic biomarker(s) identified, the most effective therapy targeting the specific molecular marker can be selected. The liquid biopsy will therefore help personalize medicines for patients based on the molecular features of their disease.

Gene 105

Gene DNA Life Science Genotype 105

Roots Analysis

AUGUST 12, 2024

These diagnostic solutions are essential for detecting and monitoring diseases, identifying genetic abnormalities, and guiding personalized treatment plans. Molecular diagnostic solutions are pivotal across various medical fields, including oncological disorders, infectious diseases, genetic testing, and personalized medicine.

Genetics 40

Genetics Gene Expression RNA DNA 40

XTalks

DECEMBER 12, 2023

The world of neuroscience trials is rapidly evolving, presenting new challenges and opportunities for researchers and clinicians. This growth is primarily being driven by a rise in neurological diseases like stroke, dementia and peripheral neuropathy, coupled with increased R&D funding for neurological research. billion in 2022.

Trials 111

Trials Clinical Trials Clinical Trials Genetics 111

Roots Analysis

APRIL 28, 2024

However, the rising incidence and prevalence of rare kidney disease, with poor outcomes and high cost has led to an increased research activity in this domain. They have been described below: Clinical Heterogeneity: This arises due to the insufficient study populations, poor access to genetic testing, and phenotypical differences.

Genetics 40

Genetics Genotype Development Research 40

The Pharma Data

SEPTEMBER 8, 2021

The acquisition enables Roche to further expand the portfolio of currently over 45 CE-IVD assays and more than 100 research use assays on Roche`s LightCycler PCR instruments. TIB Molbiol is a biotech company that has supplied the global market with reagents for research and medical diagnostics for over 30 years.

Genotype 52

Genotype Reagent Genetics Research 52

Roots Analysis

AUGUST 31, 2023

Recent advances in DNA sequencing technologies have led to significant developments in healthcare-focused research on precision medicine and diagnostics. In this context, nutrigenomics studies have demonstrated that individuals who have genetic risk alleles for obesity can hasten the weight loss with the help of some dietary modifications.

Genomics 40

Genomics Genome Genetics Gene 40

pharmaphorum

JANUARY 18, 2023

In 2016, scientists behind a study called the Resilience Project analysed genetic data from 589,000+ people and found 13 adults who carried genetic variants that should have resulted in serious – even deadly – childhood disease, but who were apparently healthy. Why should research be any different? with their priorities.

Genetic Disease 97

Genetic Disease Genetics Research Genomics 97

XTalks

APRIL 15, 2021

A 2015 study published in Nature Genetics found that the availability of human genetic data made investigational drugs twice as likely to pass pivotal trials and eventually be approved. Figure 1: The use of Mendelian randomization to validate genetic drug targets.

Development 98

Development Drugs Genomics Genome 98

XTalks

APRIL 24, 2023

Approximately 72 percent of rare diseases are genetic, and around 70 percent of rare genetic diseases emerge in childhood. Watch the free, on-demand webinar and gain valuable insights from this team of clinical research experts. Rare diseases can often be progressive, chronic and fatal.

Gene Therapy 95

Gene Therapy Gene Trials Clinical Trials 95

The Pharma Data

NOVEMBER 2, 2020

ONWARD is investigating Adial’s lead drug candidate, AD04, as a therapeutic agent for the treatment of Alcohol Use Disorder (AUD) in persons with certain target genotypes related to the serotonin transporter and receptor genes. Key ONWARD highlights include: All 25 planned investigative sites are active.

Trials 52

Trials Genotype Marketing Production 52

XTalks

MARCH 3, 2021

The US Food and Drug Administration (FDA) has granted approval to Nulibry (fosdenopterin) for reducing the risk of death associated with molybdenum cofactor deficiency type A (MoCD Type A), making it the first treatment for the ultra-rare, genetic metabolic disorder. The approval was granted to BridgeBio Pharma, Inc.

FDA Approval 64

FDA Approval Genotype Clinical Trials Clinical Trials 64

The Pharma Data

DECEMBER 9, 2020

With the launch of Overland, we are creating a robust research and development engine in parallel with the significant growth and opportunity presented by Asia’s evolving biotech industry. BioMed X – Germany-based BioMed X Institute completed its first joint research project in neuroscience with Boehringer Ingelheim.

In-Vivo 52

In-Vivo In-Vitro Antibody Development 52

The Pharma Data

NOVEMBER 18, 2020

HIV drug resistance is caused by changes in the genetic structure of HIV that affects the ability of drugs to block the replication of the virus. The recommended specimen types for HIV drug resistance genotyping are plasma or dried blood spots. Combatting antimicrobial resistance is a global. governance and enabling mechanisms.

Drugs 52

Drugs Genotype Medicine Development 52

The Pharma Data

NOVEMBER 24, 2020

PH1 is an ultra-rare genetic disease characterized by oxalate overproduction. About Primary Hyperoxaluria Type 1 (PH1) PH1 is an ultra-rare genetic disease that affects an estimated one to three individuals per million in the United States and Europe. Oxlumo should be administered by a healthcare professional.

FDA Approval 52

FDA Approval Production RNA Medicine 52

The Pharma Data

DECEMBER 9, 2020

Vigil’s pipeline strategy is to target these diseases by combining a high-level understanding of microglia physiology, disease genotyping, and patient phenotyping to identify specific genetic variations associated with microglial dysfunction. His company, which also includes Qiuqing Ang , M.D., Genesis Therapeutics.

Marketing 52

Marketing In-Vivo Protein In-Vitro 52

The Pharma Data

MARCH 16, 2022

Roche and its subsidiary, Tib Molbiol, confirm that it has tests for research use that identify the SARS-CoV-2 subvariants of concern, Omicron: BA.1, It’s critical to quickly and accurately identify variants to inform ongoing research – including the ongoing development of therapeutics and vaccines. 3 and Delta.

In-Vitro 52

In-Vitro Genotype Reagent Protein 52

pharmaphorum

FEBRUARY 17, 2022

Researchers discovered a highly virulent variant of HIV in the Netherlands that genetic sequence analysis suggests has been circulating since the 1990s. . Led by researchers from the University of Oxford ‘s Big Data Institute, the study underscores the significance of analysing viruses continually over time.

Genomics 98

Genomics Genome Genetics Genotype 98

Delveinsight

DECEMBER 16, 2020

As per the WHO, more than 100 types of HPV are found worldwide, out of them at least 13 known HPV genotypes can cause cancer of the cervix. Some of the key companies including Evofem Biosciences, QureTechBio, Vault Pharma, Genetic Immunity, and others are involved in developing treatments for Chlamydia. Trichomoniasis.

Bacteria 52

Bacteria Development Genotype Vaccine 52

XTalks

MARCH 26, 2025

XTALKS WEBINAR: Biomarker Solutions for Steatotic Liver Disease: Enabling Better Insights into MASH/MASLD Biology Live and On-Demand: Thursday, May 29, 2025 , at 11am EDT (4pm BST / UK) Register for this free webinar to discover the impact of genetic markers on the severity and treatment of MASH/MASLD.

Trials 66

Trials Life Science Clinical Trials Clinical Trials 66