Remove Genetics Remove Hormones Remove Insulin
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Researchers show novel device improves blood sugar control in hyperinsulinism patients whose pancreas has been removed

Scienmag

Philadelphia, September 13, 2021—Researchers at Children’s Hospital of Philadelphia (CHOP) have demonstrated that an experimental device can improve blood sugar control in patients who developed diabetes after their pancreas was removed to treat their hyperinsulinism, a genetic disease in which the pancreas produces too much insulin.

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What Are Biopharmaceuticals?

Pharma Packaging Solutions

Hormones (such as insulin, glucagon, and growth hormone, to name a few) are produced by recombinant DNA, as are blood factors, thrombolytic agents, interferons, monoclonal antibodies, therapeutic enzymes, and more.

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Treatment Reverses Young Man’s Type 1 Diabetes. Will It Last?

The Pharma Data

7, 2020 — After starting a drug that’s officially approved to treat a type of blood cancer, a young man with type 1 diabetes was able to stop using insulin. He’s been off insulin since August 2018 — more than two years. This patient had a genetic mutation that ruxolitinib is known to work on.

Insulin 52
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Type 1 Diabetes Vaccine: Does Diamyd Have a Winning Formula?

XTalks

A vaccine developed by Swedish company Diamyd Medical has demonstrated significant treatment efficacy in a predefined genetic subgroup of individuals with type 1 diabetes in a Phase IIb clinical trial. The trial showed a preservation of function of insulin-producing ?-cells cells at 15 months post-diagnosis. cells (see video above).

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Alnylam finds belly fat gene and drug target in UK Biobank study

pharmaphorum

Transgenic mice in which the gene has been deleted have improved control of blood glucose and insulin sensitivity. “We are currently testing this hypothesis, with the goal of pursuing a development candidate targeting INHBE in the near future,” said Paul Nioi, head of Alnylam’s human genetics group.

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From Gene to Protein: The Journey of Protein Expression Technology

Roots Analysis

Algal Expression System: This expression system is used in genetic engineering, biofuel production, botany. Hormones (includes recombinant insulin, erythropoietin and growth hormones) Enzyme replacement therapies used in treatment of rare genetic disorders such as Gaucher disease.

Protein 40
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Diamyd Medical and Critical Path Institute announce data sharing collaboration to develop advanced drug development tools in type 1 diabetes

The Pharma Data

The Phase III trial evaluated the use of the diabetes vaccine Diamyd ® , an antigen-specific immunotherapy based on the auto-antigen GAD (glutamic acid decarboxylase), to induce immunological tolerance and stop the autoimmune destruction of insulin producing cells. People with type 1 diabetes cannot produce insulin.