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Neurocrine Biosciences’ Crenessity Approved as First New Treatment in Decades for Rare Genetic Disorder CAH

XTalks

CAH is a group of rare genetic disorders affecting the adrenal glands, which produce essential hormones like cortisol, aldosterone and androgens. The most common form of CAH, 21-hydroxylase deficiency, disrupts hormone production, leading to cortisol deficiency and an overproduction of androgens.

Genetics 116
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Pancreatic Awareness Month 2024: Advancing Research to Improve Survival

XTalks

November is Pancreatic Cancer Awareness Month , a time dedicated to increasing public understanding of this challenging disease, supporting patients and their families and advancing research for better treatment options. For this reason, researchers are working hard to find new methods to identify pancreatic cancer sooner.

Research 105
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Exercise hormone may modulate genes associated with replication of novel coronavirus

Scienmag

Brazilian researchers observed that in uninfected adipocytes, the hormone irisin altered the expression of genes that regulate ACE-2, which encodes a protein to which the virus binds in order to invade human cells.

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In a first, children with rare genetic diseases get mitochondrial transplants from their mothers

STAT News

They also metabolize cholesterol and synthesize hormones and neurotransmitters. And over the next 2 billion or so years, that bacteria evolved to be the mitochondria that power nearly every cell in the human body. These capsule-shaped organelles don’t just turn oxygen and nutrients into chemical energy.

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Hormone exposure in the womb potentially linked to migraine risk in later life

Scienmag

Hormone levels in the womb before birth have been potentially linked to the risk of developing migraine in adulthood, reveals a new study of genetic and environmental information from the world’s largest database of twins.

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New genetic target for male contraception identified

Medical Xpress

Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals.

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Genetically modified mice pave the way for customized medicine in a rare disease

Medical Xpress

An international research team led by Dr. Ana Guadaño at the Alberto Sols Biomedical Research Institute (IIBM, a combined CSIC-UAM center) and involving the Complutense University of Madrid (UCM), used CRISPR gene editing techniques to incorporate into mice a mutation of the MCT8 protein responsible for transporting thyroid hormones to the interior (..)