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CAH is a group of rare genetic disorders affecting the adrenal glands, which produce essential hormones like cortisol, aldosterone and androgens. The most common form of CAH, 21-hydroxylase deficiency, disrupts hormone production, leading to cortisol deficiency and an overproduction of androgens.
November is Pancreatic Cancer Awareness Month , a time dedicated to increasing public understanding of this challenging disease, supporting patients and their families and advancing research for better treatment options. For this reason, researchers are working hard to find new methods to identify pancreatic cancer sooner.
Brazilian researchers observed that in uninfected adipocytes, the hormone irisin altered the expression of genes that regulate ACE-2, which encodes a protein to which the virus binds in order to invade human cells.
They also metabolize cholesterol and synthesize hormones and neurotransmitters. And over the next 2 billion or so years, that bacteria evolved to be the mitochondria that power nearly every cell in the human body. These capsule-shaped organelles don’t just turn oxygen and nutrients into chemical energy.
Hormone levels in the womb before birth have been potentially linked to the risk of developing migraine in adulthood, reveals a new study of genetic and environmental information from the world’s largest database of twins.
Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals.
An international research team led by Dr. Ana Guadaño at the Alberto Sols Biomedical Research Institute (IIBM, a combined CSIC-UAM center) and involving the Complutense University of Madrid (UCM), used CRISPR gene editing techniques to incorporate into mice a mutation of the MCT8 protein responsible for transporting thyroid hormones to the interior (..)
Other issues include medical systems that can often be dismissive of women’s health concerns or experiences, and historically less research on women’s health, which together, can lead to late diagnoses or misdiagnoses. Through this, researchers can pinpoint breast cancer cell types and their phenotypic states.
Philadelphia, September 13, 2021—Researchers at Children’s Hospital of Philadelphia (CHOP) have demonstrated that an experimental device can improve blood sugar control in patients who developed diabetes after their pancreas was removed to treat their hyperinsulinism, a genetic disease in which the pancreas produces too much insulin.
Latin America’s genetic diversity and unique health challenges are driving groundbreaking clinical research, offering new insights into disease prevention, innovative medicine, and treatments. The barbasco root is a plant used in Mexican traditional medicine that has been used to develop synthetic hormones. [1]
Genetic Factors : Certain genetic mutations, such as those in DNA repair genes, can affect how cells respond to radiation. Hormonal Status : A body’s hormones, such as levels of reproductive hormones and thyroid function, can impact tissue responses to radiation therapy.
Researchers from Nara Institute of Science and Technology find that the plant hormone ethylene mediates the invasion of hosts by parasitic plants Credit: Satoko Yoshida Nara, Japan – Mutants that reveal the secrets of how plants attack?
Findings have implications for seed production and crop yield and could help rewrite textbooks, translating to practical applications for plant reproduction Credit: Dr. Wangshu Mou Researchers at the University of Maryland (UMD) have discovered an entirely new role for a well-known plant molecule called ACC, providing the first clear example of ACC (..)
New research by the National Institutes of Health found that unbalanced progesterone signals may cause some pregnant women to experience preterm labor or prolonged labor. During pregnancy, the hormone progesterone helps to […]. During pregnancy, the hormone progesterone helps to […].
Research has indicated that vasomotor symptoms commonly occur during the late perimenopause and early postmenopausal years. While the exact physiology of vasomotor symptoms is not fully understood, it is believed that the significant fluctuations in reproductive hormones play a role in triggering these symptoms.
Researchers at the University of Melbourne are interested in better understanding the link between the brain and how we eat. They also want to study the contribution of stress, negative thinking patterns, and genetic and hormonal factors. Participants will be helping to advance medical research. Why Participate?
Researchers have discovered that an aggressive form of pancreatic cancer ‘hijacks’ the immune system’s response and therefore is more likely to respond to treatment with immunotherapy, raising hopes for new targets in the fight against the disease.
Hormone replacement therapy (HRT) could cut the risk of Alzheimer’s in some women at elevated risk of the disease, according to researchers in the UK. “Our research looked at associations with cognition and brain volumes using MRI scans,” noted Professor Minihane.
More Study Details About the Research Centre Study Location Research Centre: Monash University Location: 264 Ferntree Gully Rd, Notting Hill VIC 3168 Lead Researchers: Dr Elise McGlashan, Dr Ben Bullock, and Assoc. Join now and help researchers pave the way for a better understanding of bipolar disorder. Why Participate?
Bottom Line: Various genetic alterations in circulating tumor cells (CTCs) were associated with clinical outcomes and resistance to hormone therapy in patients with metastatic castrate-resistant prostate cancer (mCRPC).
More Study Details About the Research Centre: Location Research Centre: Melbourne Brain Centre Imaging Unit – University of Melbourne Location: Kenneth Myer Building, 144/30 Royal Parade, Parkville VIC 3052, Australia Lead Researcher: Professor Kim Felmingham, P.h.D, Contents About the Study Why Participate?
Study Location Research Centre: Monash Biomedical Imaging Location: 770 Blackburn Road, Clayton 3168 Lead Doctor: Professor Alex Fornito Ethics Committee: This study has been reviewed and approved by the Monash University Human Research Ethics Committee (Project #12692) Background Attention, young men! Are you a man aged 18 – 45?
This study will use brain imaging, genetics, questionnaires, and other assessments to map the brain systems and genes that underlie risk and resilience for mental health problems. You will be helping researchers to better understand how to identify people at risk of psychiatric disorders. Contents Background Why Participate?
Hormone-based therapeutics aim to delay glaucoma progression by enhancing estrogen’s potential protective effects. There are also studies examining gene therapy-based techniques to repair or replace genetic defects contributing to this disease.
22, 2020 — Pregnancy can increase the risk of a rare, dangerous heart condition called aortic dissection, researchers report. Researchers analyzed data from 29 women who were unexpectedly hospitalized for aortic dissection while pregnant. THURSDAY, Oct. Patients require lifesaving care.
While clinical researchers occasionally need to identify and validate a new surrogate endpoint for a given trial, choosing endpoints that have been previously used as the basis of NDAs and BLAs can clear the path to eventual approval. Symptoms and Etiology: Caused by an overproduction of growth hormone, acromegaly primarily affects adults.
Furthermore, the condition carries the risk of differential diagnosis as more than 50 genetic/metabolic diseases are associated with infantile spasms, and many patients have other disorders that cause developmental delays (e.g., Early diagnosis is necessary for better treatment outcomes. cerebral palsy, Down syndrome, tuberous sclerosis, etc.)
The RNA interference specialist says its researchers and collaborators have identified mutations in a gene called INHBE that are associated with protection against abdominal obesity and metabolic syndrome – a condition impacting more than 20% of adults worldwide. .
FDA’s Green Flag to Ascendis’s Once-Weekly SKYTROFA for Treatment of Pediatric Growth Hormone Deficiency. Growth Hormone Deficiency , commonly known as dwarfism, can constitute short stature and complications with metabolism, which arise due to inadequate production of growth hormones by the pituitary gland inside the body.
Hypoparathyroidism arises when the parathyroid glands fail to produce enough parathyroid hormone (PTH) or when the PTH produced is ineffective. In some cases, the cause could be autoimmune or genetic. Hypoparathyroidism is most commonly caused due to accidental injury to or the removal of the parathyroid glands.
This patient had a genetic mutation that ruxolitinib is known to work on. Forbes said it’s not clear if other people with type 1 diabetes also have this specific genetic mutation. Insulin is a hormone that ushers the sugars from foods into the body’s cells to be used as fuel. But more research is needed, she added.
More Study Details About the Research Centre Study Location Research Centre: Melbourne Brain Centre Imaging Unit, The University of Melbourne Location: Kenneth Myer Building, 30 Royal Parade, Parkville, VIC 3052, Australia Lead Researcher: Trevor Steward, Ph.D. Why Participate? Who Can Participate? Study Location What’s Next?
About the Research Center: Location. Research Center: Parexel. Lead Researcher: David Han, M.D. Achondroplasia (ACH) is a genetic condition that affects children’s growth. CNP is a hormone produced by the body that plays an important role in the bone growth of children. About the Research Center: Parexel.
With ongoing research and clinical trials , institutions like Olympian Clinical Research are at the forefront of finding innovative treatment options. Family History: Genetics plays a significant role. Hormonal Changes: Hormonal fluctuations, especially during puberty, can influence the severity and onset of psoriasis.
The Endometriosis Awareness Month 2024 campaign is focused on increasing awareness of the latest advancements in treating this condition, as well as discussing the ongoing efforts of the medical and research communities to understand and address endometriosis. Understanding Endometriosis In the US, an estimated 6.5
While the exact cause is unknown, factors like genetics, inflammation, and hormones play a role. Here are some common triggers of HS: Hormonal Changes: Many individuals with HS report flare-ups during periods of hormonal change, such as menstruation, pregnancy, or menopause.
But because it’s not often suspected in men, diagnosis often comes only after a tumor has begun to spread throughout the body, new research shows. “Approximately one-half of males with breast cancer received a diagnosis after it had already spread,” either to nearby or distant tissues, said a team of researchers at the U.S.
director of the Division of General Endocrinology in the FDA’s Center for Drug Evaluation and Research. Achondroplasia is a genetic condition that causes severely short stature and disproportionate growth. Researchers measured the participants’ annualized growth velocity, or rate of height growth, at the end of the year.
More Study Details About the Research Centre: Location Research Centre: Melbourne Brain Centre Imaging Unit – University of Melbourne Location: Kenneth Myer Building, 144/30 Royal Parade, Parkville VIC 3052, Australia Lead Researcher: Professor Kim Felmingham, P.h.D, Contents About the Study Why Participate?
It has been a year dominated by the pandemic and many life sciences research projects were put on hold as big pharma turned its attention to vaccines and therapies. But there was some considerable progress in other fields of medicine even though research efforts were diverted away, reports Richard Staines. Rare disease progress.
The buildup in adrenal glands leads to the insufficient hormonal response, thus leading to several of the symptoms such as deficiency of steroid hormones (mainly cortisol and aldosterone), impaired cortisol secretion, and others that are harbingers of the disease. The disorder can occur at any stage of life and vary with severity.
Relugolix is a once-daily, oral gonadotropin-release hormone (GnRH) receptor antagonist. X-linked myotubular myopathy (XLMTM) is a rare genetic neuromuscular disorder and leads to muscle weakness, respiratory failure, and early death. mg and norethindrone acetate (0.5 mg) in the US and Canada. The post A USD 4.2
Advise patients of these risks and the need for effective non-hormonal contraception. WELIREG can render some hormonal contraceptives ineffective. This is a rare genetic disease with an estimated incidence of 10,000 people in the U.S. WELIREG can render some hormonal contraceptives ineffective.
Frank Nestle, Sanofi’s chief scientific officer and Global Head of Research, and Dietmar Berger, Sanofi’s chief medical officer and Global Head of Development, provided an overview of the company’s clinical activities and highlighted some of the assets that will be key revenue drives for the company. That’s a significant goal.
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