Scienmag

SEPTEMBER 13, 2021

Philadelphia, September 13, 2021—Researchers at Children’s Hospital of Philadelphia (CHOP) have demonstrated that an experimental device can improve blood sugar control in patients who developed diabetes after their pancreas was removed to treat their hyperinsulinism, a genetic disease in which the pancreas produces too much insulin.

Genetic Disease 52

Genetic Disease Insulin Hormones Research 52

Pharmaceutical Technology

JANUARY 22, 2023

The mutation leads to disordered thyroid hormone transport, which causes patients to experience intellectual and motor disabilities. Egetis is banking on tiratricol, an oral small molecule that restores dysfunctional thyroid hormone signalling, to be the first drug approved for this condition.

Drugs 317

Drugs Gene Hormones Clinical Trials 317

Worldwide Clinical Trials

JULY 8, 2024

Genetic Factors : Certain genetic mutations, such as those in DNA repair genes, can affect how cells respond to radiation. Hormonal Status : A body’s hormones, such as levels of reproductive hormones and thyroid function, can impact tissue responses to radiation therapy.

Hormones 130

Hormones Regulation Clinical Trials Clinical Trials 130

Scienmag

NOVEMBER 4, 2020

Researchers from Nara Institute of Science and Technology find that the plant hormone ethylene mediates the invasion of hosts by parasitic plants Credit: Satoko Yoshida Nara, Japan – Mutants that reveal the secrets of how plants attack?

Hormones 82

Hormones Research Bioinformatics Genetics 82

Scienmag

AUGUST 14, 2020

Findings have implications for seed production and crop yield and could help rewrite textbooks, translating to practical applications for plant reproduction Credit: Dr. Wangshu Mou Researchers at the University of Maryland (UMD) have discovered an entirely new role for a well-known plant molecule called ACC, providing the first clear example of ACC (..)

Hormones 59

Hormones Production Research Genetics 59

Scienmag

MARCH 11, 2021

New research by the National Institutes of Health found that unbalanced progesterone signals may cause some pregnant women to experience preterm labor or prolonged labor. During pregnancy, the hormone progesterone helps to […]. During pregnancy, the hormone progesterone helps to […].

Hormones 74

Hormones Development Research Gene 74

XTalks

MAY 17, 2023

Research has indicated that vasomotor symptoms commonly occur during the late perimenopause and early postmenopausal years. While the exact physiology of vasomotor symptoms is not fully understood, it is believed that the significant fluctuations in reproductive hormones play a role in triggering these symptoms.

Hormones 95

Hormones FDA Approval Drugs Clinical Trials 95

Trialfacts

MAY 23, 2023

Researchers at the University of Melbourne are interested in better understanding the link between the brain and how we eat. They also want to study the contribution of stress, negative thinking patterns, and genetic and hormonal factors. Participants will be helping to advance medical research. Why Participate?

Research 52

Research Hormones Genetics Development 52

pharmaphorum

JANUARY 16, 2023

Hormone replacement therapy (HRT) could cut the risk of Alzheimer’s in some women at elevated risk of the disease, according to researchers in the UK. “Our research looked at associations with cognition and brain volumes using MRI scans,” noted Professor Minihane.

Hormones 75

Hormones Genotype Research Genetics 75

Trialfacts

JANUARY 28, 2024

More Study Details About the Research Centre Study Location Research Centre: Monash University Location: 264 Ferntree Gully Rd, Notting Hill VIC 3168 Lead Researchers: Dr Elise McGlashan, Dr Ben Bullock, and Assoc. Join now and help researchers pave the way for a better understanding of bipolar disorder. Why Participate?

Research 52

Research Hormones Genetics Drugs 52

Scienmag

MARCH 26, 2021

Bottom Line: Various genetic alterations in circulating tumor cells (CTCs) were associated with clinical outcomes and resistance to hormone therapy in patients with metastatic castrate-resistant prostate cancer (mCRPC).

Hormones 40

Hormones Genetics Research Medicine 40

Trialfacts

JANUARY 18, 2023

More Study Details About the Research Centre: Location Research Centre: Melbourne Brain Centre Imaging Unit – University of Melbourne Location: Kenneth Myer Building, 144/30 Royal Parade, Parkville VIC 3052, Australia Lead Researcher: Professor Kim Felmingham, P.h.D, Contents About the Study Why Participate?

Research 52

Research Hormones Genetics Development 52

XTalks

MARCH 13, 2024

Hormone-based therapeutics aim to delay glaucoma progression by enhancing estrogen’s potential protective effects. There are also studies examining gene therapy-based techniques to repair or replace genetic defects contributing to this disease.

Gene Therapy 111

Gene Therapy Gene Life Science DNA 111

The Pharma Data

OCTOBER 22, 2020

22, 2020 — Pregnancy can increase the risk of a rare, dangerous heart condition called aortic dissection, researchers report. Researchers analyzed data from 29 women who were unexpectedly hospitalized for aortic dissection while pregnant. THURSDAY, Oct. Patients require lifesaving care.

Cardiology 52

Cardiology Hormones Genetics Research 52

XTalks

SEPTEMBER 17, 2020

While clinical researchers occasionally need to identify and validate a new surrogate endpoint for a given trial, choosing endpoints that have been previously used as the basis of NDAs and BLAs can clear the path to eventual approval. Symptoms and Etiology: Caused by an overproduction of growth hormone, acromegaly primarily affects adults.

Trials 98

Trials Gene Hormones Clinical Trials 98

Delveinsight

SEPTEMBER 27, 2021

Furthermore, the condition carries the risk of differential diagnosis as more than 50 genetic/metabolic diseases are associated with infantile spasms, and many patients have other disorders that cause developmental delays (e.g., Early diagnosis is necessary for better treatment outcomes. cerebral palsy, Down syndrome, tuberous sclerosis, etc.)

Marketing 77

Marketing Hormones Radiology Pharma Companies 77

pharmaphorum

JULY 28, 2022

The RNA interference specialist says its researchers and collaborators have identified mutations in a gene called INHBE that are associated with protection against abdominal obesity and metabolic syndrome – a condition impacting more than 20% of adults worldwide. .

Biobanking 52

Biobanking Gene Gene Silencing Drugs 52

XTalks

AUGUST 22, 2024

Hypoparathyroidism arises when the parathyroid glands fail to produce enough parathyroid hormone (PTH) or when the PTH produced is ineffective. In some cases, the cause could be autoimmune or genetic. Hypoparathyroidism is most commonly caused due to accidental injury to or the removal of the parathyroid glands.

Hormones 52

Hormones FDA Approval Trials Clinical Trials 52

The Pharma Data

DECEMBER 17, 2020

This patient had a genetic mutation that ruxolitinib is known to work on. Forbes said it’s not clear if other people with type 1 diabetes also have this specific genetic mutation. Insulin is a hormone that ushers the sugars from foods into the body’s cells to be used as fuel. But more research is needed, she added.

Insulin 52

Insulin Genetics Doctors Doctor 52

Trialfacts

JANUARY 16, 2024

More Study Details About the Research Centre Study Location Research Centre: Melbourne Brain Centre Imaging Unit, The University of Melbourne Location: Kenneth Myer Building, 30 Royal Parade, Parkville, VIC 3052, Australia Lead Researcher: Trevor Steward, Ph.D. Why Participate? Who Can Participate? Study Location What’s Next?

Research 52

Research Hormones Genetics 52

Trialfacts

NOVEMBER 23, 2022

About the Research Center: Location. Research Center: Parexel. Lead Researcher: David Han, M.D. Achondroplasia (ACH) is a genetic condition that affects children’s growth. CNP is a hormone produced by the body that plays an important role in the bone growth of children. About the Research Center: Parexel.

Clinical Trials 52

Clinical Trials Clinical Trials Research Hormones 52

XTalks

MARCH 28, 2024

The Endometriosis Awareness Month 2024 campaign is focused on increasing awareness of the latest advancements in treating this condition, as well as discussing the ongoing efforts of the medical and research communities to understand and address endometriosis. Understanding Endometriosis In the US, an estimated 6.5

Hormones 40

Hormones Life Science In-Vitro Drugs 40

Olympian Clinical Research

NOVEMBER 6, 2023

While the exact cause is unknown, factors like genetics, inflammation, and hormones play a role. Here are some common triggers of HS: Hormonal Changes: Many individuals with HS report flare-ups during periods of hormonal change, such as menstruation, pregnancy, or menopause.

Hormones 52

Hormones Doctor Doctors Clinical Trials 52

The Pharma Data

OCTOBER 15, 2020

But because it’s not often suspected in men, diagnosis often comes only after a tumor has begun to spread throughout the body, new research shows. “Approximately one-half of males with breast cancer received a diagnosis after it had already spread,” either to nearby or distant tissues, said a team of researchers at the U.S.

Genetics 52

Genetics Hormones Research Gene 52

Trialfacts

AUGUST 2, 2023

More Study Details About the Research Centre: Location Research Centre: Melbourne Brain Centre Imaging Unit – University of Melbourne Location: Kenneth Myer Building, 144/30 Royal Parade, Parkville VIC 3052, Australia Lead Researcher: Professor Kim Felmingham, P.h.D, Contents About the Study Why Participate?

Research 52

Research Hormones Genetics Development 52

Delveinsight

JULY 30, 2020

The buildup in adrenal glands leads to the insufficient hormonal response, thus leading to several of the symptoms such as deficiency of steroid hormones (mainly cortisol and aldosterone), impaired cortisol secretion, and others that are harbingers of the disease. The disorder can occur at any stage of life and vary with severity.

Hormones 52

Hormones Marketing Gene Trials 52

The Pharma Data

AUGUST 15, 2021

Advise patients of these risks and the need for effective non-hormonal contraception. WELIREG can render some hormonal contraceptives ineffective. This is a rare genetic disease with an estimated incidence of 10,000 people in the U.S. WELIREG can render some hormonal contraceptives ineffective.

Hormones 52

Hormones Clinical Trials Clinical Trials Trials 52

The Pharma Data

JANUARY 7, 2021

Frank Nestle, Sanofi’s chief scientific officer and Global Head of Research, and Dietmar Berger, Sanofi’s chief medical officer and Global Head of Development, provided an overview of the company’s clinical activities and highlighted some of the assets that will be key revenue drives for the company. That’s a significant goal.

Protein 52

Protein Antibody Genetics Gene Therapy 52

XTalks

NOVEMBER 12, 2024

November is Pancreatic Cancer Awareness Month , a time dedicated to increasing public understanding of this challenging disease, supporting patients and their families and advancing research for better treatment options. For this reason, researchers are working hard to find new methods to identify pancreatic cancer sooner.

Research 105

Research FDA Approval Trials Clinical Trials 105

XTalks

FEBRUARY 14, 2024

The extensive research in developing more effective and less toxic treatments, such as targeted therapies, immunotherapies and precision medicine , has helped to considerably improve the survival rates for many types of childhood cancers.

Hormones 52

Hormones Development Genetics Life Science 52

Trialfacts

NOVEMBER 30, 2023

Stuart Phillips IRB: This study has been reviewed and approved by the Hamilton Integrated Research Ethics Board (HiREB) under Project #16408 About the Study We all know that resistance training is a powerful tool to rebuild lost muscle mass, but did you know that what you eat plays a crucial role in enhancing these effects? Why Participate?

Protein 52

Protein Research Hormones Containment 52

Roots Analysis

OCTOBER 24, 2023

Owing to the advancement in clinical pharmacology and oncology domain, and the rising demand for targeted therapeutics and precision medicines, high potency active pharmaceutical ingredients (HPAPIs) and cytotoxic drugs have become one of the key areas of interest to researchers and drug manufacturers across the globe.

Manufacturing 40

Manufacturing Hormones Contamination Containment 40

The Pharma Data

JANUARY 11, 2021

Brown fat generates heat by drawing glucose from the bloodstream, as opposed to energy-storing white fat, explained senior researcher Dr. Paul Cohen. But research now shows that adults who have active brown fat tissues in their bodies are far less likely than their peers to suffer from a range of chronic illnesses. ” Cypess said.

Medicine 52

Medicine Research Hormones Genetics 52

Olympian Clinical Research

MARCH 3, 2023

In contrast, pediatric eczema is typically associated with genetics and family history. When we are under stress, our bodies release cortisol, a hormone that can weaken the skin’s natural barrier and make it more susceptible to irritation and inflammation. Stress Stress is a known trigger for adult eczema outbreaks.

Clinical Research 52

Clinical Research Production Containment Research 52

Delveinsight

JANUARY 7, 2021

Omega Funds led the series B round with assists from fellow new investor Fidelity Management & Research and existing backers Atlas Venture, OrbiMed, and Bristol Myers Squibb, which became involved through its Celgene acquisition. Biotheranostics’ two PCR-based genetic tests are well established in the U.S.:

RNA 52

RNA Clinical Trials Clinical Trials Bioavailability 52

The Pharma Data

JUNE 2, 2023

Eliav Barr, senior vice president, head of global clinical development and chief medical officer, Merck Research Laboratories, said, “It is imperative that we create new ways to treat advanced cancers and help improve patient outcomes by building on the current standard of care. In the U.S., For the U.S.

FDA Approval 52

FDA Approval HR Trials Hormones 52

Olympian Clinical Research

MARCH 1, 2024

Genetics, hormonal changes, and certain medications can also play a role in developing age spots. Years of sun exposure can damage the skin, leading to premature aging and age spots.

Dermatology 52

Dermatology Production Cosmetics Hormones 52