Scienmag

APRIL 14, 2022

In a Policy Forum, Anna Lewis and colleagues argue that, for researchers and others who want to invoke genetic ancestry, there is a scientific and ethical imperative to move away from continental ancestry categories and to instead embrace a view of genetic ancestry that reflects continuous variation and historical depth.

Genetics 123

Genetics Medicine Research 123

Medical Xpress

MAY 8, 2023

Scientists at the National Institutes of Health have identified new genetic risk factors for two types of non-Alzheimer's dementia. These findings were published in Cell Genomics and detail how researchers identified large-scale DNA changes, known as structural variants, by analyzing thousands of DNA samples.

Genetics 98

Genetics DNA Research Genome 98

Pharmaceutical Technology

DECEMBER 23, 2022

Eli Lilly and Company has expanded a licencing and partnership agreement with ProQR Therapeutics to discover, develop and market new genetic medicines. The post Lilly and ProQR to expand genetic medicine development agreement appeared first on Pharmaceutical Technology.

Genetics 328

Genetics Medicine Development Gene Therapy 328

AuroBlog - Aurous Healthcare Clinical Trials blog

DECEMBER 21, 2022

Scientists have found an extremely subtle twist in the genetics of aging cells, one that seems to make them increasingly less functional as time goes on.

Genetics 172

Genetics Gene Scientist Research 172

Medical Xpress

APRIL 26, 2023

Researchers from Children's Hospital of Philadelphia (CHOP) and Princeton University have discovered a novel genetic disorder associated with neurodevelopmental differences. The discovery identified the disorder in 21 families from all over the world.

Genetics 101

Genetics Research Protein 101

STAT News

MARCH 14, 2023

Saying genetics researchers inconsistently and inappropriately use racial and ethnic labels that fail to capture the complex patterns of human genetic variation, the National Academies of Sciences, Engineering, and Medicine issued a report Tuesday calling for a transformation in how such descriptors are used.

Genetics 98

Genetics Research Genome Genomics 98

Drug Discovery World

JUNE 19, 2024

New research has uncovered how different people respond to sepsis based on their genetics, which could lead to the development of targeted therapies. This provides insight into how an individual’s genetic makeup influences how they respond to sepsis and who would benefit from targeted therapies.

Genetics 64

Genetics Immune Response Genome Genomics 64

Drug Discovery World

OCTOBER 5, 2023

A research team at the Francis Crick Institute and Great Ormond Street Hospital (GOSH)/UCL Great Ormond Street Institute of Child Health have identified potential treatments for children with rare genetic conditions. The researchers have shown that problems with calcium underlie these progressive diseases.

Genetics 59

Genetics Research Gene Doctors 59

Pharmaceutical Technology

MARCH 24, 2023

Moderna has entered a strategic partnership with Generation Bio for the development of non-viral genetic medicines. Moderna’s biological and technical expertise will be combined with core technologies of the non-viral genetic medicine platform from Generation Bio.

Genetics 130

Genetics Medicine Development In-Vivo 130

AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 14, 2023

Indian healthcare looks at pharmacogenomics, the study of influence of genetic factors on drug response, in patient care as comprehensive genetic tests gain ground.

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Genetics Drugs Clinical Trials Clinical Trials 146

Medical Xpress

FEBRUARY 24, 2023

A team of researchers at the University of Georgia has identified the source of several symptoms in patients suffering from familial dysautonomia (FD), a rare and debilitating genetic disease that primarily affects children.

Genetic Disease 75

Genetic Disease Genetics Research 75

Medical Xpress

DECEMBER 20, 2022

New research findings have revealed an underlying genetic cause for why some children who have had COVID-19 infection develop Multisystem Inflammatory Syndrome in Children (MIS-C), a rare but potentially life-threatening disease.

Genetics 97

Genetics Research Development 97

Medical Xpress

MARCH 7, 2023

A simple vitamin could successfully treat a rare but potentially fatal genetic disease, according to research led by a Concordia undergraduate student.

Genetics 98

Genetics Genetic Disease Research 98

Pharma Times

JUNE 19, 2024

Congenital melanocytic naevus syndrome can cover up to 80% of the bodies of children

Genetics 124

Genetics Research 124

Medical Xpress

MARCH 14, 2023

National Institutes of Health researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced. The results of this study, published in Biological Psychiatry, may help researchers develop more precise treatments to improve cognition in people with Down syndrome.

Genetics 72

Genetics Development Research 72

Worldwide Clinical Trials

FEBRUARY 6, 2023

When using genetic screening to identify clinical trial volunteers, a sponsor’s obligations for further testing and disclosure of results to patients and families are unclear, especially when the results have no impact on medical management. Guidance in this area is much needed. Read the full article! Read the full article!

Genetics 130

Genetics Clinical Trials Clinical Trials Genotype 130

Medical Xpress

MARCH 2, 2023

How many children an individual may have is influenced by reproductive biology and human behavior, according to the largest study to date, which identifies genetic determinants.

Genetics 73

Genetics Research Genome Genomics 73

Pharmaceutical Technology

JUNE 4, 2023

In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Transcription factors for genetically modified cells. However, not all innovations are equal and nor do they follow a constant upward trend.

Genetics 130

Genetics Gene Expression DNA Antibody 130

pharmaphorum

JANUARY 18, 2023

In 2016, scientists behind a study called the Resilience Project analysed genetic data from 589,000+ people and found 13 adults who carried genetic variants that should have resulted in serious – even deadly – childhood disease, but who were apparently healthy. Why should research be any different? with their priorities.

Genetic Disease 77

Genetic Disease Genetics Research Genome 77

Scienmag

SEPTEMBER 29, 2021

Describing a previously unknown genetic condition that affects children, researchers at University of California San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine say they also found a potential method to prevent the gene mutation by administering a drug during pregnancy.

Genetics 84

Genetics Research Genome Genomics 84

Pharmaceutical Technology

FEBRUARY 15, 2023

In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Genetically modified animal models. Regeneron Pharmaceuticals is one of the leading patent filers in the generation of genetically modified animal models.

Genetics 130

Genetics DNA Antibody Genome 130

Pharma Times

MAY 30, 2024

Affecting the immune system, various forms of SCID are estimated to affect one in 75,000 to 100,000 newborns

Genetics 114

Genetics Research 114

Pharma Times

JUNE 19, 2024

The serious condition is responsible for approximately 11 million deaths worldwide every year

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Genetics Research Genome Genomics 122

BioSpace

OCTOBER 6, 2022

This week, researchers presented findings in how ancestry affects cancer treatment, nanotechnology and genetic diseases. Here's a look at that and more.

Genetic Disease 79

Genetic Disease Genetics Research 79

Pharmaceutical Technology

MAY 25, 2023

The Medicines and Healthcare products Regulatory Agency (MHRA) aims to launch a pilot genetic biobank that will gather patient data to associate drug-related adverse events to their genetic makeup. The first patients will have their genetic makeup sequenced in Spring 2024 and this data will be shared in 2025.

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Biobanking Genetics Genome Project Genome 130

Pharma Times

FEBRUARY 9, 2024

The rare neurodevelopmental condition CDKL5 is characterised by early-onset epilepsy

Genetics 136

Genetics Research 136

Medical Xpress

MARCH 21, 2023

The cellular glitches underlying a rare genetic disorder called activated PI3K Delta syndrome 2 (APDS2) have been identified by researchers at the Garvan Institute of Medical Research. The disorder is caused by genetic variations that disrupt immune cell signaling through a protein called PI3K.

Genetics 84

Genetics Protein Research 84

Scienmag

JULY 12, 2022

July 11, 2022, CLEVELAND: New research from Cleveland Clinic is demonstrating that pathogenic polymerase epsilon and delta (POLE/POLD1) genetic mutations lead to improved response to immune checkpoint blockade, a powerful class of immunotherapy drugs.

Genetics 79

Genetics Clinical Research Research Drugs 79

Medical Xpress

NOVEMBER 29, 2022

Genetically modified and attenuated measles viruses are considered a promising platform for research and development of vector vaccines and oncolytic measles viruses.

Genetics 74

Genetics Vaccination Vaccine Research 74

Advarra

MARCH 31, 2023

The use of engineered genetic materials in clinical trials is rapidly expanding, with potential applications for genetic vaccines, gene-modified cellular therapies, and gene therapies. A key part of the IBC’s evaluation is assessing the risks posed by the engineered genetic materials.

Engineer 52

Engineer Genetics Clinical Research Research 52

Bio Pharma Dive

JANUARY 4, 2024

The CRISPR specialist joins some of its genetic medicine peers in trimming staff, announcing an “organizational streamlining” to focus resources on prioritiy drug programs.

Genetics 177

Genetics Research Medicine Drugs 177

Scienmag

JULY 4, 2022

Medical and life science researchers will benefit from the most comprehensive atlas yet of genetic data on zebrafish, newly published research suggests. The atlas will help researchers to better study conditions from various types of cancer (e.g. skin cancer), heart disease, and neurodegeneration.

Genetics 61

Genetics Research Life Science 61

Medical Xpress

FEBRUARY 7, 2023

The provider asks the patient some basic questions, like alcohol cravings and stress levels, and collects a blood sample for genetic testing. Imagine a patient has been diagnosed with alcohol use disorder, and their health care provider is reviewing medication options to help them curb their drinking.

Genetics 95

Genetics Doctors Doctor Research 95

Drug Discovery World

DECEMBER 13, 2022

Boston Children’s Hospital researchers will use HiFi whole-genome sequencing (HiFi WGS) for the purpose of investigating genetic and epigenetic variants associated with rare paediatric diseases. As causative variants are identified by CRDC researchers, results are returned to participants.

Genetics 52

Genetics Research Genome Genomics 52

Medical Xpress

NOVEMBER 30, 2022

In any given cell at any given time, molecular processes are underway to seal cracks in the double helix or proofread the genetic code, all part of a perpetual upkeep program that maintains the body's status quo and staves off disease.

Genetics 96

Genetics Genetic Disease DNA Research 96

Olympian Clinical Research

SEPTEMBER 27, 2023

While the exact cause of vitiligo remains a subject of ongoing research, genetics has emerged as a significant factor in understanding its onset and progression. In this deep dive, we’ll explore the genetic links associated with vitiligo and address the burning question: Is vitiligo hereditary?

Genetics 52

Genetics Gene Clinical Research Research 52

Medical Xpress

MARCH 23, 2023

Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds—and possibly streamline the diagnosis and treatment of gliomas, a study suggests.

Genetics 105

Genetics Research 105