Bio Pharma Dive

FEBRUARY 23, 2023

Graphite Bio and Sangamo are stopping work on their respective sickle cell gene therapies, while Intellia revealed partner Novartis ended development of its genetic treatment for the blood disease.

Gene Therapy 264

Gene Therapy Gene Development Genetics 264

Pharmaceutical Technology

FEBRUARY 13, 2023

While several therapeutics are available for treating symptoms associated with epilepsy, researchers and patients have strongly called out the need for more holistic treatments that would address the condition as a whole. Meanwhile, others are researching the link between gene variation and different responses to treatments.

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Research Gene Gene Therapy Genome 264

Bio Pharma Dive

DECEMBER 12, 2021

But despite continued setbacks, drug developers are hopeful that genetic technologies and a better understanding of biology will bring new options in the not-too-distant future The fatal nerve disease has few treatments.

Genetics 264

Genetics Drugs Research Development 264

Bio Pharma Dive

MARCH 1, 2023

At a time when many startups have struggled to gain cash, the biotech has raised another $135 million to back its research, a new twist on genetic medicine.

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Genetics Medicine Research 321

Worldwide Clinical Trials

DECEMBER 19, 2024

At the recent World Orphan Drug Congresses (WODC) in Europe and the United States, Worldwide Clinical Trials Derek Ansel , Vice President, Therapeutic Strategy Lead, Rare Disease, facilitated roundtable discussions to explore the operational challenges and ethical barriers surrounding genetic testing.

Genetics 130

Genetics In-Vitro Drugs Clinical Trials 130

AuroBlog - Aurous Healthcare Clinical Trials blog

SEPTEMBER 17, 2024

We are witnessing a revolution in healthcare, driven by advances in genetics, Omics, RNA and CRISPR gene-editing technology, to deliver precision and personalised medicine, said Kiran Mazumdar-Shaw, executive chairperson, Biocon and Biocon Biologics. This holds the potential to cure genetic diseases that have plagued families for generations.

Genetic Disease 159

Genetic Disease Genetics Gene Editing Medicine 159

AuroBlog - Aurous Healthcare Clinical Trials blog

SEPTEMBER 30, 2024

Researchers see a greater need for new generation therapeutics to propel precision medicine. The development of innovative therapeutic approaches in healthcare encompass a variety of fields, including gene therapy, personalized medicine, immunotherapy, and advanced biologics.

Medicine 167

Medicine Research Gene Therapy Genetics 167

Bio Pharma Dive

SEPTEMBER 12, 2024

Spun out of research at Nationwide Children’s Hospital, Vironexis claims it will be the first company to start a study testing a cancer drug delivered via the adeno-associated viruses commonly used in genetic medicines.

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Gene Therapy Gene Genetics Trials 290

XTalks

MAY 23, 2024

One of the more intriguing developments in cancer research in recent years is the growing understanding of clonal hematopoiesis, a phenomenon where blood cells expand from a single clone due to genetic mutations. Clonal hematopoiesis increases in prevalence with age and can precede hematologic malignancies.

Genetics 114

Genetics Research Genome Genomics 114

Pharmaceutical Technology

MARCH 1, 2024

1910 Genetics has entered an agreement with Microsoft, aiming to revitalise pharmaceutical research and development (R&D) productivity.

Genetics 130

Genetics Production Development Research 130

Bio Pharma Dive

JANUARY 4, 2024

The CRISPR specialist joins some of its genetic medicine peers in trimming staff, announcing an “organizational streamlining” to focus resources on prioritiy drug programs.

Genetics 195

Genetics Research Medicine Drugs 195

Bio Pharma Dive

APRIL 1, 2022

Taysha Gene Therapies is narrowing its research efforts and cutting around 35% of its workforce, the latest in a series of layoffs announced by makers of genetic medicines.

Gene Therapy 289

Gene Therapy Gene Development Genetics 289

Bio Pharma Dive

FEBRUARY 12, 2021

Lysosomal storage disorders, diseases of cellular metabolism gone wrong, are the focus of a fast-expanding lineup of experimental genetic medicines, a research boom that recalls biotech's roots.

Gene Therapy 290

Gene Therapy Gene Genetics Medicine 290

Pharma Times

FEBRUARY 9, 2024

The rare neurodevelopmental condition CDKL5 is characterised by early-onset epilepsy

Genetics 138

Genetics Research 138

Worldwide Clinical Trials

DECEMBER 12, 2022

Genetic testing provides patients with a diagnosis for their illness, helps patients and family members to understand risks of developing new diseases, and can be used to support clinical trial advancement. What are the benefits and limitations to using genetic testing? It is important to consider the type of testing performed (e.g.,

Clinical Trials 130

Clinical Trials Clinical Trials Genetics Trials 130

AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 14, 2023

Indian healthcare looks at pharmacogenomics, the study of influence of genetic factors on drug response, in patient care as comprehensive genetic tests gain ground.

Genetics 152

Genetics Drugs Clinical Trials Clinical Trials 152

Bio Pharma Dive

SEPTEMBER 9, 2021

billion, expands Lilly's work in genetic medicine research. An agreement with the Dutch biotech, which could be worth as much as $1.3

RNA 264

RNA Genetics Medicine Research 264

Medical Xpress

DECEMBER 27, 2024

UT Southwestern Medical Center researchers have identified a genetic mutation that slows the growth of melanoma and potentially other cancers by harnessing the power of the immune system.

Genetics 99

Genetics Medicine Research 99

Pharmaceutical Technology

MARCH 24, 2023

Moderna has entered a strategic partnership with Generation Bio for the development of non-viral genetic medicines. Moderna’s biological and technical expertise will be combined with core technologies of the non-viral genetic medicine platform from Generation Bio.

Genetics 130

Genetics Medicine Development In-Vivo 130

AuroBlog - Aurous Healthcare Clinical Trials blog

JUNE 25, 2024

A woman in Colombia with rare genetic resistance to Alzheimer’s disease may have more company than scientists thought.

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Gene Genetics Scientist Research 205

Bio Pharma Dive

FEBRUARY 25, 2021

Sean Nolan and Joe Nolan, former leaders at the Zolgensma developer, are behind Jaguar Gene Therapy, which plans to research treatments for a rare metabolic disease as well as genetically linked autism and diabetes.

Gene Therapy 260

Gene Therapy Gene Genetics Development 260

AuroBlog - Aurous Healthcare Clinical Trials blog

DECEMBER 25, 2024

Researchers studied cancer growth in mice. Nature, 2024) Aging brings two opposing trends in cancer risk: first, the risk climbs in our 60s and 70s, as decades of genetic mutations build up in our bodies. Zhuang et al., But then, past the age of around 80, the risk drops again and a new study […]

Genetics 213

Genetics Research Clinical Trials Clinical Trials 213

Pharma Times

JUNE 19, 2024

Congenital melanocytic naevus syndrome can cover up to 80% of the bodies of children

Genetics 128

Genetics Research 128

Worldwide Clinical Trials

FEBRUARY 6, 2023

When using genetic screening to identify clinical trial volunteers, a sponsor’s obligations for further testing and disclosure of results to patients and families are unclear, especially when the results have no impact on medical management. Guidance in this area is much needed. Read the full article! Read the full article!

Genetics 130

Genetics Clinical Trials Clinical Trials Genotype 130

Pharmaceutical Technology

APRIL 30, 2024

Unlock the potential of genetic modification with Precision Biosciences Inc's patented MTEM technology for precise editing of eukaryotic cells. Discover how this mitochondria-targeting engineered meganuclease is revolutionizing genetic research.

Engineer 195

Engineer DNA Genetics Research 195

Pharma Times

AUGUST 19, 2024

In the UK study, researchers analysed 2,023 bowel cancers from the 100,000 Genomes Project

Genome Project 112

Genome Project Genetics Research Genome 112

Pharmaceutical Technology

FEBRUARY 15, 2023

In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Genetically modified animal models. Regeneron Pharmaceuticals is one of the leading patent filers in the generation of genetically modified animal models.

Genetics 130

Genetics DNA Genome Genomics 130

Pharmaceutical Technology

JUNE 4, 2023

In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Transcription factors for genetically modified cells. However, not all innovations are equal and nor do they follow a constant upward trend.

Genetics 130

Genetics Gene Expression DNA Gene 130

STAT News

FEBRUARY 9, 2023

Researchers who believe genomics can transform human health love to recount success stories. They’ll tell you about the 3-month-old boy whose heart was failing until researchers pinpointed what was ailing him. Read the rest…

Genetic Disease 119

Genetic Disease DNA Genetics Genome 119

Pharma Times

JUNE 19, 2024

The serious condition is responsible for approximately 11 million deaths worldwide every year

Genetics 126

Genetics Research Genome Genomics 126

AuroBlog - Aurous Healthcare Clinical Trials blog

SEPTEMBER 9, 2024

The convergence of gene therapies and clinical research is pushing the boundaries of what’s possible in ophthalmic care, offering hope for more effective treatments and potential cures for a range of vision-threatening conditions.

Gene Therapy 198

Gene Therapy Gene Genetics Clinical Research 198

Pharmaceutical Technology

NOVEMBER 8, 2022

Cyagen and Neurophth Therapeutics have entered a strategic partnership to jointly develop next-generation AAV gene therapy vectors for specific kinds of genetic ophthalmic ailments. Under the collaboration, Cyagen is entitled to get research phase and clinical phase milestone payments and sales-based royalty payments totalling over $140m.

Gene Therapy 305

Gene Therapy Gene Development Genetics 305

Pharmaceutical Technology

MAY 25, 2023

The Medicines and Healthcare products Regulatory Agency (MHRA) aims to launch a pilot genetic biobank that will gather patient data to associate drug-related adverse events to their genetic makeup. The first patients will have their genetic makeup sequenced in Spring 2024 and this data will be shared in 2025.

Biobanking 130

Biobanking Genetics Genome Project Genome 130

Pharma Times

MAY 30, 2024

Affecting the immune system, various forms of SCID are estimated to affect one in 75,000 to 100,000 newborns

Genetics 116

Genetics Research 116

Medical Xpress

MAY 11, 2023

Using new genetic tools to study statins in human cells and mice, Stanford Medicine researchers and collaborators have uncovered how the cholesterol-lowering drugs protect the cells that line blood vessels.

Research 137

Research Genetics Medicine Drugs 137

Pharmaceutical Technology

MAY 17, 2023

The deal will see the integration of Scribe’s new CRISPR by Design approach and Prevail’s expertise in developing genetic medicines for neurological disorders for specific genetic targets. Scribe will receive $75m, including an upfront payment and equity investment via a convertible note.

Genetics 130

Genetics Medicine In-Vivo Gene Therapy 130

AuroBlog - Aurous Healthcare Clinical Trials blog

SEPTEMBER 22, 2024

(Richard Jones/Science Photo Library/Getty Images) Scientists have discovered hundreds of genes that could potentially promote cancer, new research shows. Cancer is typically triggered by some kind of change to our genetic coding that interferes with a cell’s ability to manage its growth.

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Scientist Gene Genetics Research 197