Bio Pharma Dive

DECEMBER 12, 2023

Based on the work of MIT scientists, the well-funded startup is developing ways to insert large sizes of genetic material anywhere in the genome without damaging or breaking DNA.

Genome 332

Genome Genomics DNA Genetics 332

Scienmag

JULY 19, 2022

One reason is a person’s genetic proclivity to abuse substances. […]. CHAPEL HILL, NC – Have you ever wondered why one person can smoke cigarettes for a year and easily quit, while another person will become addicted for life? Why can’t some people help themselves from abusing alcohol and others can take it or leave it?

Genetics 77

Genetics Scientist 77

Medical Xpress

MAY 14, 2023

For two decades, scientists have been comparing every person's full set of DNA they study to a template that relies mostly on genetic material from one man affectionately known as "the guy from Buffalo."

DNA 98

DNA Scientist Genome Genomics 98

AuroBlog - Aurous Healthcare Clinical Trials blog

JUNE 25, 2024

A woman in Colombia with rare genetic resistance to Alzheimer’s disease may have more company than scientists thought.

Gene 191

Gene Genetics Scientist Research 191

AuroBlog - Aurous Healthcare Clinical Trials blog

JUNE 19, 2023

The research – first brought to wider attention by The Guardian – has prompted excitement about the potential for new breakthroughs in health, genetics, and treating disease. In a major scientific first, synthetic human embryo models have been grown in the lab, without any need for the usual natural ingredients of eggs and sperm.

Scientist 191

Scientist Genetics Research Clinical Trials 191

Medical Xpress

MAY 8, 2023

Scientists at the National Institutes of Health have identified new genetic risk factors for two types of non-Alzheimer's dementia. These findings were published in Cell Genomics and detail how researchers identified large-scale DNA changes, known as structural variants, by analyzing thousands of DNA samples.

Genetics 98

Genetics DNA Research Genome 98

AuroBlog - Aurous Healthcare Clinical Trials blog

JUNE 8, 2023

As DNA holds the genetic code controlling how our bodies grow and are maintained, that’s a serious problem that […] The artificial sweetener sucralose (marketed as Splenda) is widely used and found in products like diet soda and chewing gum.

DNA 189

DNA Scientist Genetics Production 189

Scienmag

JULY 8, 2022

Scientists have identified more than 1,500 genetic differences between migratory and non-migratory hoverflies. Credit: Will Hawkes Scientists have identified more than 1,500 genetic differences between migratory and non-migratory hoverflies.

Scientist 85

Scientist Gene Genetics 85

Drug Discovery World

JUNE 11, 2024

In research published in Nature today, scientists at the Crick journeyed into a ‘gene desert’ – an area of DNA that doesn’t code for proteins – which has previously been linked to IBD and several other autoimmune diseases. The researchers are now working with LifeArc to find ways to deliver MEK inhibitors directly to macrophages.

Genetics 59

Genetics Research Gene Scientist 59

Scienmag

OCTOBER 26, 2020

New genetic sensors, developed by scientists at University of Warwick and Keele University, could function as a lab test device and even as a live monitoring system inside living cells The innovative system can detect when a specific gene in a cell is active – instead of only detecting its presence The technology is based […].

Genetics 75

Genetics Scientist Gene Development 75

STAT News

FEBRUARY 16, 2023

Zhang, one of the leading scientists in the groundbreaking field of genetic editing, had reached out two days prior to discuss a new company he was working on. Akin Akinc was scouring his email spam box last summer, looking for a missing message, when he stumbled across an unexpected email from a quite recognizable name: Feng Zhang.

Genetics 142

Genetics DNA Genome Genomics 142

Medical Xpress

FEBRUARY 14, 2023

Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have removed a major roadblock to better understanding of mpox (formerly, monkeypox).

Scientist 98

Scientist Development Allergies Genetics 98

BioSpace

JULY 14, 2021

The next COVID pandemic could be prevented by using a gene drive to preemptively edit the genome of bats to prevent them from becoming hosts for coronaviruses, according to a proposal by scientists from Israel’s Interdisciplinary Center Herzelia and the National Institutes of Health.

Scientist 99

Scientist Genetics Genome Genomics 99

Scienmag

JULY 22, 2022

Genome sequencing, where scientists use laboratory methods to determine a specific organism’s genetic makeup, is becoming a common practice in insect research.

Genome 82

Genome Genomics Scientist Research 82

Scienmag

JULY 5, 2022

Scientists have revealed the genetic and molecular structure of key molecules linked to the sometimes life-threatening mammalian-meat allergy brought on by tick bites.

Allergies 79

Allergies Genetics Scientist Research 79

Scienmag

MARCH 30, 2021

Credit: Mark Milburn/Atlantic Scuba Red algae that grow in Cornwall’s Fal Estuary are genetically unique, new research shows. University of Exeter scientists studied the population genetics of Phymatolithon calcareum, a coralline red algal species that forms maerl beds in shallow coastal seas from Portugal to Norway.

Scientist 93

Scientist Genetics Research 93

Scienmag

MAY 31, 2021

NIH- and USU- led study links ALS to a fat manufacturing gene and maps out a genetic therapy Credit: Courtesy of the NIH/NINDS.

Genetics 56

Genetics Scientist Gene Manufacturing 56

Scienmag

MARCH 30, 2021

Credit: Gretel Nicholson, EXRC Scientists have discovered a new genetic disease, which causes some children’s brains to develop abnormally, resulting in delayed intellectual development and often early onset cataracts.

Genetic Disease 52

Genetic Disease Genetics Scientist Development 52

Medical Xpress

FEBRUARY 6, 2023

Scientists may have solved the question of why Ashkenazi Jews are significantly more susceptible to a rare genetic disorder known as Gaucher disease—and the answer may help settle the debate about whether they are less susceptible to tuberculosis (TB).

Genetics 75

Genetics Genetic Disease Scientist 75

pharmaphorum

JANUARY 24, 2023

Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates. The logical extension to this kind of approach is treating individual patients, with their individual genetic makeup.

Genetics 97

Genetics Drugs Genome Project Biobanking 97

Medical Xpress

NOVEMBER 30, 2022

In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides—the basic structural unit of DNA coded in the base of chemicals cytosine (C), adenine (A), guanine (G) and thymine (T)—is repeated multiple times in tandem.

Genetics 98

Genetics DNA Scientist 98

Medical Xpress

NOVEMBER 22, 2022

Scientists at University of Florida (UF) Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The compound restored the health of neurons in the lab and rescued mice with the disease.

RNA 76

RNA Scientist Genetics Development 76

Medical Xpress

DECEMBER 1, 2022

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

Genetics 75

Genetics Scientist 75

Drug Discovery World

APRIL 9, 2024

Scientists have found that certain molecules called chemokines, specifically CXCL9 and CXCL10, play a crucial role in attracting immune cells, particularly activated T cells, to the tumour site.

Genetic Engineering 52

Genetic Engineering Engineer Genetics Immune Response 52

pharmaphorum

MARCH 21, 2024

Surgeons in the US have carried out the world’s first transplant of a pig kidney into a human, a feat made possible by genetic modification of the organ and an experimental immunosuppressant drug regimen to prevent rejection.

Scientist 108

Scientist Genetics Drugs 108

STAT News

FEBRUARY 21, 2023

BEIJING — Hong Kong on Tuesday revoked a visa it granted to a Chinese scientist who set off an ethical debate five years ago with claims that he made the world’s first genetically edited babies, pulling it hours after he announced his research plans in the financial hub.

Scientist 98

Scientist Genetics Licensing Licensing 98

Scienmag

MARCH 29, 2021

Tissue collection at NOAA Fisheries lab helps reveal genetic distinction Credit: Mansur/WCR Bangladesh New genetic analysis and years of painstaking research has revealed that one of the world’s most endangered marine mammals is actually two species rather than one, as scientists had long assumed.

Genetics 86

Genetics Genetic Analysis Scientist Research 86

Scienmag

APRIL 15, 2021

Team of Japanese and European scientists identify a novel genetic mitochondrial disorder by analyzing DNA samples from three distinct families Credit: Fujita Health University DNA ligase proteins, which facilitate the formation of bonds between separate strands of DNA, play critical roles in the replication and maintenance of DNA.

Genetics 105

Genetics DNA Genome Genomics 105

Scienmag

NOVEMBER 19, 2021

LA JOLLA, CA—New research shows how genetic variations linked to severe cases of COVID-19 affect our immune cells. Credit: La Jolla Institute for Immunology LA JOLLA, CA—New research shows how genetic variations linked to severe cases of COVID-19 affect our immune cells.

Genetics 94

Genetics Scientist Research 94

Pharma Times

JUNE 25, 2021

Genetic changes could be used to guide treatment for the rare and aggressive cancer type

Genetics 95

Genetics Scientist 95

Medical Xpress

NOVEMBER 10, 2022

Scientists at the University of Pittsburgh School of Medicine have discovered the missing puzzle piece in the mystery of how melanoma tumors control their mortality.

Scientist 76

Scientist Genetics Medicine 76

Scienmag

JUNE 28, 2022

Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed “T cell exhaustion” by scientists. Now, researchers at Gladstone Institutes and Stanford University have revealed the genetic switches that get […].

Scientist 80

Scientist Genetics Research Medicine 80

Bio Pharma Dive

JUNE 2, 2022

Severino left the pharma company in April after eight years as its chief scientist and then president. He'll lead Tessera Therapeutics, a well-funded genetic medicine startup.

Pharma Companies 274

Pharma Companies Genetics Scientist Medicine 274

pharmaphorum

JANUARY 18, 2023

In 2016, scientists behind a study called the Resilience Project analysed genetic data from 589,000+ people and found 13 adults who carried genetic variants that should have resulted in serious – even deadly – childhood disease, but who were apparently healthy. Giving participants something in return.

Genetic Disease 95

Genetic Disease Genetics Research Genome 95

Medical Xpress

FEBRUARY 28, 2023

Northwestern Medicine scientists have identified the cause of a genetic subtype of autism and schizophrenia that results in social deficits and seizures in mice and humans.

Genetics 75

Genetics Scientist Medicine 75

Drug Discovery World

JANUARY 19, 2024

UK scientists have uncovered the interplay between cancer-driving genetic mutations and inherited genetic variants in a rare type of blood cancer. The study describes how inherited genetic variants can influence whether a spontaneous mutation in a particular gene increases the risk of developing this rare blood cancer.

Genetics 59

Genetics Gene DNA Development 59

STAT News

APRIL 19, 2023

But after Cheung herself developed a genetic condition so rare it doesn’t have an official name, causing her to start losing her vision, HHMI decided to stop funding her.

Scientist 136

Scientist Genetic Disease Genetics Research 136