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Magazine: Genomic projects exploit scale as clinical applications play catch-up

Pharmaceutical Technology

This month, we take a look at emerging research in this area , including that from the United Kingdom’s 100,000 Genomes Project, and understand how clinical applications could follow in the near future. You can also subscribe here to receive email notifications when a new issue is available.

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Parexel, NeoGenomics partner on oncology genomics project

Outsourcing Pharma

The two companies will work to advance precision cancer medicine by harnessing genomics data in trial design, recruitment, site selection and other areas.

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COSMIC database matches drugs to cancer mutations

pharmaphorum

The COSMIC (Catalogue of Somatic Mutations in Cancer) database, operated by the Wellcome Sanger Institute, grew out of the work of the Cancer Genome Project and has been gathering data on mutations associated with specific cancers for almost 17 years.

Drugs 59
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The future of genomic medicine: can it fulfil its promises?

pharmaphorum

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. This is where the future of medicine lies – where we are able to read a patient’s genome and then direct care and therapy based upon that.”.

Genomics 119
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A history of blood cancer treatment

pharmaphorum

Although clinical trials proved that chemicals could be used to treat cancer, the results of the study remained a closely guarded military secret until 1946. 2012 – The 100,000 Genomics Project begins. Unlocking the secrets of the human genome has intrigued investigators for centuries.

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Exa-Cel CRISPR Gene Therapy for Sickle Cell Disease Deemed Safe by FDA Advisory Panel

XTalks

The companies used data from the 1,000 Genomes Project but from that, only 61 datasets made the cut to encompass the ideal patient population. “I The FDA scientists agreed that Vertex’s clinical trial results, made available in documents published last week, were “strongly positive.”

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New research across its oncology portfolio at the virtual American Association for Cancer Research (AACR) Annual Meeting 2021

The Pharma Data

The data include an oral presentation in a Clinical Trials Plenary Session on April 10 on the Phase III trial CHRONOS-3 evaluating copanlisib (Aliqopa ) in combination with rituximab in patients with relapsed indolent non-Hodgkin’s Lymphoma (iNHL). Israel and Taiwan under the brand name Aliqopa. o Abstract 394; April 10, 8:30am EDT.