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Supercharging AI-drug discovery with strategic multiomic biobanks 

Drug Discovery World

Narain , PhD, President and CEO of BPGbio asks how a better calibre of biobanks in life sciences can lead to more drugs making it to market. In anticipation of the long-awaited personalised medicine revolution, many different types of biobanks have emerged to catalogue samples. But the utility of biobanks varies.

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How Pharmacogenomics may finally realise its promise

pharmaphorum

There have been great strides made in genomics to refine tools that determine the safest, most effective course of treatments for patients across a number of disease states. Looking at an individual’s genomic profile also provides an understanding of appropriate medication dosage.

Genome 85
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Rare Disease Diagnosis: Why Tackling the Genomic Analysis Bottleneck is Key to Advancing Precision Medicine

XTalks

For more information on tackling this “genomic analysis bottleneck,” watch this on-demand webinar. HS: Due to the heterogeneity of the rare disease population, there are many relevant gene lists, and the genomic data analysis of these patients covers almost 2,000 different genetic targets.

Genome 98
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Why a recent advancement is a giant leap for human genomics

Drug Discovery World

The first complete, gapless sequence of a human genome was published 1 April 2022 in a special issue of the journal Science 1. While The Human Genome Project mapped about 92% of the human genome two decades ago, sequencing the last 8% of the genome proved highly challenging.

Genome 52
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10 Key Learnings from Successful Cellular and Gene Therapy Trials for Rare Diseases

XTalks

According to Dr. Melanie Blank, clinical team leader for General Medicine Branch 1 at the US Food and Drug Administration’s (FDA) Division of Clinical Evaluation and Pharmacology/Toxicology (DCEPT), the agency is seeing one or two new applications coming in every week for new gene therapies for different diseases.

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Biorepositories as a Guiding Resource for Research & Drug Discovery

XTalks

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Genuity Science focuses on population genomics as a tool to derive novel biological insights through partnerships with industry-leading pharmaceutical and biotech companies.

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How biomarkers can help discover new treatments for women’s health

Drug Discovery World

RA: You’ve recently announced a collaboration with the University of Oxford to access genotype data on women with endometriosis. SG: Endometriosis is a common disease that causes chronic pain and reduced fertility, reducing the quality of life of over 200 million women around the world.

Genome 72