AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 1, 2022

As drug companies have embarked on an initiative to launch affordable medicines for rare diseases in India, experts have called for using pharmacogenetics to develop treatments and whole genome sequencing to identify etiologies. There […].

Development 189

Development Genome Genomics Medicine 189

pharmaphorum

JUNE 13, 2022

Canary Wharf’s bid to become a new hub for the life sciences sector in the UK has been given a boost following the decision by Genomics England to relocate to the development. It was announced three years after the European Medicines Agency (EMA) relocated from the site to Amsterdam as a result of the UK’s exit from the EU.

Genomics 111

Genomics Genome Life Science Genome Project 111

pharmaphorum

OCTOBER 31, 2022

Verge Genomics has joined a select group of biotechs who have taken a drug discovered and developed using artificial intelligence into human testing. Since then others have followed suit, including BenevolentAI with its BEN-2293 candidate for atopic dermatitis and Insilico Medicine with idiopathic pulmonary fibrosis therapy SM001-055.

Genome 136

Genome Genomics Drugs RNA 136

pharmaphorum

NOVEMBER 27, 2022

A group representing pharma companies selling precision therapies for cancer has called for a change to the way genomic testing is done in Scotland, to make sure patients get access to targeted drugs. The post Genomic testing ‘should be offered to all cancer patients in Scotland’ appeared first on. Why not lead?”

Genome 104

Genome Genomics Genetics Medicine 104

STAT News

APRIL 12, 2023

LONDON — Using genome sequencing greatly expanded the number of diagnoses researchers could provide for children with developmental disorders from thousands of families across the United Kingdom and Ireland, researchers reported in a new study Wednesday. Read the rest…

Genomics 98

Genomics Genome Medicine Research 98

Scienmag

AUGUST 7, 2020

Credit: UTHSC Neil Hayes, MD, MS, MPH, division chief of Hematology and Oncology at the University of Tennessee Health Science Center, is among recipients of the 2020 Team Science Awards from the American Association for Cancer Research (AACR) for his contributions to developing The Cancer Genome Atlas (TCGA), a groundbreaking multisite project to (..)

Genomics 86

Genomics Genome Research Development 86

Pharmaceutical Technology

MAY 17, 2023

Under the deal, Prevail obtains exclusive rights to use Scribe’s CRISPR X-Editing (XE) technologies to develop the medicines. The deal will see the integration of Scribe’s new CRISPR by Design approach and Prevail’s expertise in developing genetic medicines for neurological disorders for specific genetic targets.

Genetics 130

Genetics Medicine In-Vivo Gene Therapy 130

pharmaphorum

SEPTEMBER 12, 2022

Alongside drugs and therapeutics, data collection and technology enhancements have redefined the traditional healthcare experience, especially within oncology, and genomic profiling has become a significant factor in allowing for personalised care. Tailored oncology. In other words, every person’s cancer has its own genetic construct.

Genome 106

Genome Genomics Clinical Trials Clinical Trials 106

pharmaphorum

MARCH 24, 2022

There’s a rich history of finding useful medicines from fungi, from the antibiotic penicillin to immune suppressant cyclosporine and cholesterol drug lovastatin. The post GSK partners LifeMine on fungi-derived medicines appeared first on. Image by jggrz from Pixabay .

Medicine 105

Medicine Genome Genomics Engineer 105

Pharmaceutical Technology

JUNE 16, 2023

The deal is aimed at advancing life sciences across three strategic areas: clinical and translational research, capacity building and technology transfer, and in the area of commercialisation.

Life Science 130

Life Science Genetic Disease Genome Genomics 130

Medical Xpress

FEBRUARY 21, 2023

A large research project, led by scientists at Sylvester Comprehensive Cancer Center in the University of Miami Miller School of Medicine, Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical College, has found that whole genome sequencing (WGS) can provide much more information about classic Hodgkin lymphoma (cHL) than exome sequencing, (..)

Genomics 72

Genomics Genome Research Protein 72

Scienmag

JULY 23, 2021

Jude Children’s Research Hospital study highlights the power of comprehensive whole genome, whole exome and RNA sequencing to better understand and treat each patient’s cancer Credit: St. Jude Children’s Research Hospital St.

Medicine 96

Medicine Genomics Genome RNA 96

Scienmag

FEBRUARY 12, 2021

Research offers new lead for cancer drug discovery Credit: Rensselaer Polytechnic Institute TROY, N.Y. — An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the “guardian of the genome” for its ability to repair DNA damage or destroy cancerous cells.

Genomics 98

Genomics Genome DNA Protein 98

Scienmag

JULY 26, 2021

American Heart Association Scientific Statement DALLAS, July 26, 2021 — Genomic studies have produced advances in how to calculate and reduce heart-disease risk, however, the benefits don’t necessarily apply to people from historically marginalized racial and ethnic groups and Indigenous populations.

Genomics 71

Genomics Genome Research Cardiology 71

Pharmaceutical Technology

SEPTEMBER 1, 2022

According to the latest deal, Merck will collaborate with Guardant’s data researchers on a range of treatment development activities that leverage the genomics and clinical information available using the GuardantINFORM platform. This approach aids in expediting next-generation cancer therapy research and development.

Development 162

Development Genome Genomics Medicine 162

Scienmag

SEPTEMBER 30, 2021

LA JOLLA—(September 30, 2021) Salk Assistant Professor Graham McVicker has been awarded a National Human Genome Research Institute (NHGRI) Genomic Innovator Award, which supports early-career scientists who conduct innovative, creative research in genomics. The award, which provides $2.85

Genomics 76

Genomics Genome Scientist Research 76

Scienmag

FEBRUARY 4, 2021

The study will leverage genomics and digital technologies to better understand factors that contribute to obesity and type 2 diabetes LA JOLLA, CA–Scripps Research, a globally recognized nonprofit biomedical research institute, today announced a collaborative research program with Tempus, a leader in precision medicine and artificial intelligence, (..)

Research 89

Research Genome Genomics Medicine 89

Scienmag

SEPTEMBER 29, 2021

Describing a previously unknown genetic condition that affects children, researchers at University of California San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine say they also found a potential method to prevent the gene mutation by administering a drug during pregnancy.

Genetics 84

Genetics Research Genome Genomics 84

STAT News

MARCH 14, 2023

Saying genetics researchers inconsistently and inappropriately use racial and ethnic labels that fail to capture the complex patterns of human genetic variation, the National Academies of Sciences, Engineering, and Medicine issued a report Tuesday calling for a transformation in how such descriptors are used. Read the rest…

Genetics 98

Genetics Research Genome Genomics 98

Pharmaceutical Technology

MAY 25, 2023

The Medicines and Healthcare products Regulatory Agency (MHRA) aims to launch a pilot genetic biobank that will gather patient data to associate drug-related adverse events to their genetic makeup. The Yellow Card biobank will launch as a joint venture with the UK-government funded entity Genomics England on June 1.

Biobanking 130

Biobanking Genetics Genome Project Genomics 130

Scienmag

JULY 21, 2021

By a team of researchers from the Faculty of Medicine & Surgery at the University of Malta Pregnancy-induced diabetes, also known as gestational diabetes, is a common metabolic complication of pregnancy. The disorder carries a significant risk of adverse obstetric outcome.

Genomics 74

Genomics Genome Research Medicine 74

XTalks

MAY 23, 2024

One of the more intriguing developments in cancer research in recent years is the growing understanding of clonal hematopoiesis, a phenomenon where blood cells expand from a single clone due to genetic mutations. Clonal hematopoiesis increases in prevalence with age and can precede hematologic malignancies.

Genetics 114

Genetics Research Genome Genomics 114

pharmaphorum

APRIL 14, 2021

More than 5,000 collaborative studies were thwarted by GDPR rules in 2019 – but is there a way to protect sensitive data while still allowing international health research to thrive? . Said the authors: “Health research is crucial for all. The mechanisms by which GDPR endangers research are multiple and complex.

Research 145

Research Regulation Genome Genomics 145

Outsourcing Pharma

JUNE 1, 2022

The Lifebit CloudOS will be employed to create a Federate Trusted Research Environment within the centerâs supercomputing cluster to handle data management.

Genomics 72

Genomics Genome Medicine Research 72

Pharmaceutical Technology

FEBRUARY 15, 2023

Genomic medicine researchers at Sanofi are accelerating progress toward gene and cell therapies using an array of technologies, from nucleic acid nanostructures to viral and non-viral gene-delivery platforms. Sanofi is one of the leading patent filers working with viral vectors.

Gene Therapy 246

Gene Therapy Gene Genome Genomics 246

Outsourcing Pharma

FEBRUARY 18, 2021

The two companies will work to advance precision cancer medicine by harnessing genomics data in trial design, recruitment, site selection and other areas.

Genome Project 66

Genome Project Genomics Genome Medicine 66

BioTech 365

JUNE 23, 2021

Pacific Biosciences and Rady Children’s Institute for Genomic Medicine Announce its First Research Collaboration for Whole Genome Sequencing Pacific Biosciences and Rady Children’s Institute for Genomic Medicine Announce its First Research Collaboration for Whole Genome Sequencing HiFi Sequencing will be … Continue reading →

Genomics 40

Genomics Genome Medicine Research 40

Scienmag

MAY 31, 2021

By including multi-ethnic participants, a largescale genetic study has identified more regions of the genome linked to type 2 diabetes-related traits than if the research had been conducted in Europeans alone.

Genomics 75

Genomics Genome Genetics Research 75

Scienmag

JUNE 28, 2021

McIndoe, bioinformatics expert and associate director of the Center for Biotechnology and Genomic Medicine at the Medical College of Georgia, is leading a dynamic, new $6.2 million federally funded initiative to support highly innovative research ideas in three areas with tremendous impact on health.

Bioinformatics 75

Bioinformatics Research Genome Genomics 75

Scienmag

JANUARY 24, 2022

Link to full release with images: Credit: Mark Stone/University of Washington Link to full release with images: [link] FROM: James Urton University of Washington 206-543-2580 jurton@uw.edu (NOTE: researcher contact information at end) For Immediate Release Jan.

Genome 74

Genome Genomics Research Medicine 74

Scienmag

NOVEMBER 3, 2020

Credit: Encarnacion/UConn Photo The advent of genome science has given researchers an unprecedented ability to understand the root causes of a host of conditions.

Genetics 71

Genetics Genomics Genome Research 71

Scienmag

OCTOBER 13, 2020

NCI-MATCH precision medicine trial makes major contributions to the use of tumor gene testing to select treatment for patients; new data has broad relevance in medicine and provides a roadmap for future precision medicine trials Credit: ECOG-ACRIN Cancer Research Group Five years ago, the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and National Cancer (..)

Clinical Trials 88

Clinical Trials Clinical Trials Trials Genomics 88

The Pharma Data

OCTOBER 26, 2021

The AVENIO Tumor Tissue Comprehensive Genomic Profiling (CGP) Kit is the first jointly-developed product that brings together the expertise and reach of Roche with Foundation Medicine’s pioneering leadership in genomic science. Cancer is a disease of the genome and treatment no longer depends solely on the tissue of origin.

Genome 52

Genome Genomics Research Medicine 52

Pharmaceutical Technology

FEBRUARY 26, 2023

Regulatory concerns remain Overall, microbiome research has not advanced as much as expected, which is partly due to safety issues, says Hota. Though the pandemic disrupted research in general, it was particularly difficult to conduct research that relied on stool samples, adds Hota.

Bacteria 278

Bacteria Trials Research Medicine 278

Scienmag

APRIL 28, 2021

In collaboration with VGP, the research group has published a research paper in Nature on platypus and echidna genomes early this year (see report in the right column).

Genomics 64

Genomics Genome Research Drugs 64

pharmaphorum

OCTOBER 19, 2022

million ($40 million) first-round financing that will be used to explore so-called ‘dark’ regions of the human genome. M Ventures’ Dr Bauke Anninga said that that the startup has a “differentiated platform technology has the potential to fundamentally shift the way we discover and develop precision medicines.

Genomics 59

Genomics Genome Gene Gene Expression 59

BioTech 365

FEBRUARY 22, 2021

Twist Bioscience and Berry Genomics to Offer New NGS Solution to Advance Research and Precision Medicine Twist Bioscience and Berry Genomics to Offer New NGS Solution to Advance Research and Precision Medicine SOUTH SAN FRANCISCO, Calif.–(BUSINESS

Genomics 40

Genomics Genome Medicine Research 40