pharmaphorum

OCTOBER 12, 2022

David Del Bourgo (CEO and co-founder, Whitelab Genomics) has always been passionate about introducing disruptive, innovative technologies to markets. We founded Whitelab Genomics after realising the potential to use data, data science, and AI in a more systematic way to develop genomic therapies,” Del Bourgo says.

Genome 105

Genome Genomics Medicine Development 105

pharmaphorum

OCTOBER 31, 2022

Verge Genomics has joined a select group of biotechs who have taken a drug discovered and developed using artificial intelligence into human testing. The post Verge Genomics takes AI-sourced drug for ALS into clinic appeared first on.

Genome 136

Genome Genomics Drugs RNA 136

Scienmag

MARCH 12, 2021

Credit: The Wistar Institute PHILADELPHIA — (March 12, 2021) — Scientists at The Wistar Institute identified a new function of ADAR1, a protein responsible for RNA editing, discovering that the ADAR1p110 isoform regulates genome […].

RNA 92

RNA Protein Genome Genomics 92

Medical Xpress

DECEMBER 29, 2022

A clinical research team from the University of Hong Kong (HKUMed) has used amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis to help more families with tailored clinical management. The findings have been published in the journal, npj Genomic Medicine.

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RNA Genome Genomics Clinical Research 75

Scienmag

OCTOBER 27, 2020

In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis. A recent addition to the toolkit, RNA sequencing, has been demonstrated to help researchers narrow down disease candidate variants identified first on exome and genome sequencing.

Genetic Disease 69

Genetic Disease RNA Genetics Genome 69

pharmaphorum

JANUARY 19, 2022

The collaboration aims to “close the gap between single-cell RNA sequencing wet-lab services and single-cell data analysis solutions,” which will allow scientists to study the finest details that can be hard to access. Research Instruments is the main distributor for genomic and life science research products in the region.

RNA 72

RNA Research Life Science Bioinformatics 72

pharmaphorum

OCTOBER 5, 2020

The only industry-led meeting showcasing the recent development of RNA editing mechanisms and dedicated to realizing the research and therapeutics opportunity of RNA editing as quickly as possible. The post 2nd RNA Editing Summit 2020 appeared first on. Visit our website: www.rna-editing-summit.com.

RNA 52

RNA Genome Genomics Research 52

World of DTC Marketing

DECEMBER 29, 2020

Both the Pfizer and Moderna vaccines copied RNA sequence from the virus genome and found a way to manufacture it at scale with high-level processes and quality control. First, a novel approach was used that didn’t require traditional vaccine production in cell cultures or eggs. 1455NO-HEALTH-CORONAVIRUS_VACCINES_PFIZER_O_.

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Vaccine Vaccination Development Clinical Trials 307

STAT News

JANUARY 30, 2023

The human genome was sequenced in 2003. It is now possible to treat diseases with gene therapy, antisense oligonucleotides, messenger RNA (mRNA), noncoding RNA (known as small interfering RNA, or siRNA), and other gene-based modalities. That said, a lot has changed in science and drug development since 1983.

RNA 111

RNA Gene Therapy Drugs Gene 111

Scienmag

MARCH 9, 2022

— Each simple RNA virus has a genome, its “native RNA.” This genome dictates how the virus replicates in cells to eventually cause disease. The genome also has the code for making a capsid, the protein shell of a virus that encapsulates the genome and protects it like a nanocontainer. RIVERSIDE, Calif.

Packaging 84

Packaging Packaging Genetics Genome 84

BioTech 365

MAY 17, 2021

NanoString’s GeoMx Mouse Whole Transcriptome Atlas Expands Leadership in Spatial Genomics by Enabling Genome-Wide RNA Profiling NanoString’s GeoMx Mouse Whole Transcriptome Atlas Expands Leadership in Spatial Genomics by Enabling Genome-Wide RNA Profiling Accelerating Discovery by Providing High Throughput Spatial Analysis … Continue (..)

Genome 40

Genome Genomics RNA 40

BioSpace

OCTOBER 7, 2020

10X Genomics just agreed to acquire ReadCoor, Inc., The $350 million deal comes on the heels of 10x Genomics’ August acquisition of CartaNA AB, a Stockholm-based developer of in situ RNA analysis technology. an innovator in the nascent field of in situ technology.

Genome 58

Genome Genomics RNA Marketing 58

Scienmag

JUNE 8, 2021

Recent advances in the genomic profile of LUAD have identified a number of driver alterations in specific genes, enabling molecular classification and targeted therapy accordingly. Credit: ©Science China Press The incidence rate of lung adenocarcinoma (LUAD) is increasing gradually and the mortality is still high.

RNA 91

RNA Genome Genomics Gene 91

Roots Analysis

AUGUST 17, 2023

Genome sequencing has historically been classified into DNA sequencing and RNA sequencing. DNA sequencing generates data that is very robust, reproducible, insightful, and can be applied to genes having different expression level by selecting genomic region. between 2022 and 2035.

RNA 52

RNA DNA Genomics Genome 52

BioTech 365

MARCH 24, 2021

Ocean Genomics Partners With Geninus to Co-Develop RNA-Based Biomarkers and Advance Research Ocean Genomics Partners With Geninus to Co-Develop RNA-Based Biomarkers and Advance Research PITTSBURGH–(BUSINESS WIRE)–#RNA–Ocean Genomics (Pittsburgh, PA), a world leader in AI-based gene expression analysis and RNA biomarker … Continue (..)

RNA 40

RNA Genome Genomics Gene Expression 40

Scienmag

JULY 23, 2021

Jude Children’s Research Hospital study highlights the power of comprehensive whole genome, whole exome and RNA sequencing to better understand and treat each patient’s cancer Credit: St. Jude Children’s Research Hospital St.

Medicine 96

Medicine Genome Genomics RNA 96

BioTech 365

JUNE 28, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Outsmarting cancer with RNA, ‘genome-tuning’ drugs and other gene-altering therapies.Outsmarting cancer with RNA, ‘genome-tuning’ drugs and other gene-altering therapies arlene.weintraub Tue, 06/22/2021 (..)

RNA 40

RNA Genome Genomics Gene 40

Scienmag

OCTOBER 29, 2020

29, 2020– A new study published online in the Annals of the American Thoracic Society examines whether the amount of RNA, or genomic load, of SARS-CoV-2 detected in swab tests of patients being admitted to the hospital with viral pneumonia is associated with more severe COVID-19. Credit: American Thoracic Society Oct.

RNA 60

RNA Genome Genomics Medicine 60

Pharmaceutical Technology

FEBRUARY 15, 2023

The swift development and deployment of messenger-RNA (mRNA) vaccines against the SARS-CoV-2 virus during the COVID-19 crisis has catapulted the pharmaceuticals industry into a new paradigm. RNA has the potential to underpin breakthrough treatments for a wide variety of diseases, including many cancers, and transform medicine as we know it.

Bioassay 130

Bioassay RNA Development Drugs 130

Scienmag

NOVEMBER 26, 2021

. — To the untrained eye, the loops, kinks and folds in the single strand of RNA that makes up the coronavirus genome look like a jumble of spaghetti or tangled yarn. But to researchers like Amanda Hargrove, a chemistry professor at Duke University, the complex shapes that RNA takes on as it folds […].

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RNA Genome Genomics Research 82

Scienmag

FEBRUARY 22, 2021

Nowakowski An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome. Amunts and D.

Genome 52

Genome Genomics RNA Research 52

Medical Xpress

FEBRUARY 2, 2023

Researchers at the Hong Kong University of Science and Technology (HKUST) developed a novel technology which allows genomic DNA and RNA sequencing to be carried out simultaneously in single cells of both frozen and fresh tissues, and identified rare brain tumor cell "spies" disguised as normal cells with this method.

RNA 94

RNA DNA Genome Genomics 94

Pharmaceutical Technology

MARCH 28, 2023

The gene-editing technology allows for precise, directed changes to genomic DNA. The system comprises the Cas9 enzyme and a guide RNA. It edits genes by precisely cutting DNA, then allowing natural DNA repair processes to take over.

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Gene Editing Gene DNA Gene Therapy 235

pharmaphorum

JULY 20, 2022

Armed with a $100 million second-round financing, CAMP4 Therapeutics is preparing to start the first clinical trial of a drug targeting regulatory RNA (regRNA) molecules that can be used to fine-tune the expression of genes. ” The post CAMP4 raises $100m to take lead RNA drugs into clinic appeared first on.

RNA 52

RNA Genetic Disease Drugs Protein 52

BioTech 365

JUNE 23, 2021

Genomic Testing Cooperative Completes New York State Approval and Medicare (Palmetto) Coverage for all DNA and RNA Tests Offered for Molecular Profiling of Hematologic and Solid Tumors Genomic Testing Cooperative Completes New York State Approval and Medicare (Palmetto) Coverage for … Continue reading →

Genome 40

Genome Genomics RNA DNA 40

Scienmag

NOVEMBER 20, 2020

Scientists at Goethe University within the international consortium COVID19-NMR refine previous 2D models The genetic code of the SARS-CoV2 virus is exactly 29,902 characters long, strung through a long RNA molecule. It contains the information for the production of 27 proteins.

Genome 70

Genome Genomics RNA Protein 70

Roots Analysis

AUGUST 28, 2022

As a result, industry and non-industry stakeholders, are on the lookout for advanced platforms that can simultaneously capture the arrangement of multiple biomolecules (DNA, RNA, proteins and others) with single-cell or subcellular resolution. 70+ spatial Genomics solutions are developed by industry and non-industry players.

Genome 52

Genome Genomics RNA Genome Project 52

Pharmaceutical Technology

JUNE 23, 2022

Coronaviruses, like Covid-19, are a notorious group of infectious agents that include a large class of viruses with RNA genomes, similar to the human DNA genome, that depend on well-organised protein structures crucial for viral growth and replication.

Drugs 130

Drugs Protein Genome Genomics 130

BioTech 365

DECEMBER 1, 2021

Genomic Testing Cooperative to Present data at the American Society of Hematology Meeting on its Proprietary Machine Learning Approaches for RNA Transcriptome Data and on the Use of Liquid Biopsy Genomic Testing Cooperative to Present data at the American Society … Continue reading →

Genome 40

Genome Genomics RNA 40

pharmaphorum

OCTOBER 13, 2020

It is also looking to expand its RNA silencing research, potentially bringing it into competition with biotech heavyweights such as Alnylam, something that Mortazavi focused on during his long time at the helm of Silence Therapeutics. The company has considerably more cash than at the start of the year – on 31 July it had £15.1

Gene Silencing 100

Gene Silencing Gene RNA Genomics 100

XTalks

OCTOBER 21, 2020

The Duke researchers developed statistical methods to identify adaptive changes that arose specifically in the SARS-CoV-2 genome in humans, but not in closely related coronaviruses found in bats and pangolins. Moreover, Berrio says the changes likely affected the folding and function of viral RNA.

RNA 98

RNA Protein Genomics Genome 98

XTalks

AUGUST 5, 2020

In recent webinars by Genuity Science, formerly known as WuXi NextCODE, experts from the biotech and pharma industries spoke about leveraging the power of single cell RNA sequencing platforms and solutions in conjunction with machine learning technologies such as AI in cell biology and disease research. The Power of Single Cell Technology.

Gene Expression 112

Gene Expression Development RNA Drugs 112

BioTech 365

JANUARY 26, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Using machine learning to identify ancient RNA viruses in the human genome.A team of researchers affiliated with multiple institutions in Japan has used machine learning algorithms to … Continue reading →

RNA 40

RNA Genome Genomics Research 40

pharmaphorum

OCTOBER 5, 2022

Sanofi has added to its rare disease pipeline by licensing an antibody-RNA conjugate (ARC) for facioscapulohumeral muscular dystrophy (FSHD), a genetic muscle disorder, from US biotech miRecule. billion deal in 2018.

RNA 105

RNA Genetics Dermatology Antibody 105

Scienmag

SEPTEMBER 30, 2020

Now, researchers reporting in ACS Central Science have identified small molecules that target a structure within the RNA genome […]. Scientists are fighting back with multiple strategies, including vaccines, repurposed drugs developed for other diseases and brand-new therapies.

RNA 40

RNA Genome Genomics Branding 40

Pharmaceutical Technology

FEBRUARY 23, 2023

Moderna Genomics general manager and chief scientific officer Eric Huang said: “Through our collaboration with Life Edit, we hope to harness the power of gene editing technologies as part of our broader research and development engine, helping to advance our mission and deliver on the promise of mRNA.”

Gene Editing 147

Gene Editing Gene In-Vivo Gene Therapy 147

BioTech 365

APRIL 13, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scaling up genome editing in tiny worms.Understanding the effects of specific mutations in gene regulatory regions—the sections of DNA and RNA that turn genes on and off—is … Continue reading →

Genome 40

Genome Genomics RNA DNA 40