The Pharma Data

OCTOBER 19, 2020

Spectrum and Rutgers Clinical Genomics Laboratory (RUCDR, now IBX) first identified, then introduced the nation to the key benefits of using saliva collected exclusively with the SDNA-1000 saliva collection system as a better viral diagnostic biomaterial for COVID-19 detection. Photo: Business Wire).

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Pharmaceutical Technology

FEBRUARY 3, 2023

The field of genomic medicine has reached a true turning point. More efficient, suspension-based cell culture processes are urgently needed in the now fast-developing genomic medicine space. Two-Plasmid Packaging System for Recombinant Adeno-Associated Virus. CEVEC became part of Cytiva in October 2022. 1] BioNews.

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The Pharma Data

JANUARY 17, 2021

It received FDA guidance January 5 th and is in the midst of preparing the first package of investigational new drug (IND) applications – usually with an n-of-1, for individual patients. Patient dosing is expected to begin later this year. “No No one has ever done this before,” Stanley Crooke, M.D.,

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Cloudbyz

AUGUST 9, 2023

Future-proofing Clinical Research The nature of clinical research is evolving, with personalized medicine, genomics, and digital health becoming more prominent. Streamlined workflows, reduced errors, enhanced scalability, and quicker trial durations all contribute to cost efficiencies.

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FDA Law Blog

NOVEMBER 2, 2023

Regarding the risk of hepatotoxicity with high doses: “An arbitrary upper limit of the total vector genome dose or total capsid dose is not recommended, as it is hard to standardize vector measurements across studies or to determine if there is an appropriate upper limit… Assays for empty capsids need better standardization.”

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The Pharma Data

MARCH 20, 2021

An overview of the genome organization of SARS-CoV-2 is presented in Figure 1A. The nucleocapsid protein forms a supercoiled helix structure and helps package the single stranded viral RNA genome with at least 1,000 nucleocapsid molecules per virion ( 23 , 24 ). SARS-CoV-2 proteome.

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Roots Analysis

OCTOBER 30, 2023

Self-amplifying RNA (saRNA): Self amplifying RNA is an engineered form of RNA, combining the amplifying genome (native to certain viruses) to the therapeutic gene of interest. This allows generation of multiple copies of the gene of interest at the target owing to the amplification property of the template.

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The Pharma Data

OCTOBER 14, 2020

Live replicating orthopoxviruses, like vaccinia or horsepox, can be engineered to express foreign genes and have been explored as platforms for vaccine development because they possess; (1) large packaging capacity for exogenous DNA inserts, (2) precise virus-specific control of exogenous gene insert expression, (3) lack of persistence or genomic integration (..)

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The Pharma Data

MARCH 7, 2022

“The beauty of this approach is we can safely upregulate specific genes to affect cell activity without permanently changing the genome and cause unintended mistakes,” Levy said. PRC2 can be blocked with chemicals, but they are imprecise, affecting PRC2 function throughout the genome. it can be reawakened.

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Pharmaceutical Technology

DECEMBER 9, 2022

In regards to the latter, notable examples include the acquisition of Cergentis, a genomics-focused biotechnology company based in the Netherlands. The deal allows the company to provide proprietary technology and knowledge steeped in fast-evolving genomic techniques that support effective decision-making and R&D program design.

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The Pharma Data

AUGUST 6, 2020

See “Worldwide Pro Forma Revenue” in Quarterly Package of Financial Information for this quarter, which is available on bms.com/investors/financial-reporting/quarterly-results, for information on the revenue of the company and Celgene on a stand-alone basis for the prior-year period. In May, the company announced the U.S.

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XTalks

FEBRUARY 11, 2021

The Human Genome Project recently marked 20 years since the publication of the first full sets of human genomic sequences, an endeavor that spanned well over a decade. Today, new next-generation sequencing technologies allow for the sequencing of complex genomes within just a day or two.

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XTalks

NOVEMBER 11, 2024

Machine learning tools are transforming genome mining, allowing AI to identify antimicrobial compounds, like biosynthetic gene clusters, and predict resistance patterns early. By 2024, about 80 percent of pharmaceutical companies had adopted these packaging changes, marking a step forward in responsible antibiotic use and AMR prevention.

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XTalks

NOVEMBER 1, 2024

Meatable also partnered with Sticta Biologicals to develop a genome-scale metabolic model of porcine cells, optimizing nutrients for cell growth with more yield and reduced variability. This oven’s AI-driven features also offer insights into temperature regulation and nutrient preservation.

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FDA Law Blog

DECEMBER 6, 2024

The draft guidance recommends that no more than 15 questions are included in the briefing package. CBER will not commit to reviewing packages greater than 250 pages. The draft guidance states that a pre-BLA meeting request should be submitted at least 4 months before the anticipated BLA submission.

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The Pharma Data

MAY 5, 2021

New variant-hardy AbCellera-Lilly mAb shows utility of viral genomics surveillance ( BioCentury ). BD Taps Contract Packager for COVID-19 Test Kits ( MD+DI ). BD Taps Contract Packager for COVID-19 Test Kits ( MD+DI ). Merck KGaA raises forecast for full year 2021 ( Pharmaletter ).

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The Pharma Data

DECEMBER 22, 2020

22, 2020 (Healthday News) — As Congress passed a $900 billion pandemic relief package on Monday, U.S. Instead, it may have been identified there first because the British government has a strong monitoring system that has tracked tens of thousands of genomic sequences of virus samples. TUESDAY, Dec.

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