The Pharma Data
MARCH 25, 2021
IBRANCE may impair fertility in males and has the potential to cause genotoxicity. Advise women not to breastfeed during IBRANCE treatment and for 3 weeks after the last dose because of the potential for serious adverse reactions in nursing infants. Advise male patients to consider sperm preservation before taking IBRANCE.
The Pharma Data
FEBRUARY 8, 2021
IBRANCE may impair fertility in males and has the potential to cause genotoxicity. Advise women not to breastfeed during IBRANCE treatment and for 3 weeks after the last dose because of the potential for serious adverse reactions in nursing infants. Advise male patients to consider sperm preservation before taking IBRANCE.
The Pharma Data
MAY 13, 2021
Exposure to sorbitol during lactation causes metabolic alterations and genotoxic effects in rat offspring. Proceedings of the National Academy of Sciences of the United States of America. 2012;109(16):5984-5988. DOI: 10.1073/pnas.1120794109. 1120794109. Cardoso FS, Araujo-Lima CF, Aiub CA, Felzenszwalb I. Toxicol Lett. 2016;260:36-45.
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