XTalks

NOVEMBER 26, 2020

In addition to innovative new antibody drugs and mRNA vaccines, researchers have found that the sleep-regulating hormone melatonin may also offer protection against COVID-19. Melatonin, which regulates the body’s circadian rhythm and sleep-wake cycle, is also available in pill form for use as a sleep aid.

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Research Hormones Protein Regulation 98

XTalks

NOVEMBER 9, 2022

GLP-1 receptor agonists, or incretin (metabolic hormones) mimetics, are analogs of the GLP-1 peptide hormone that binds to the GLP-1 receptor to regulate blood sugar levels by boosting insulin secretion. Accordingly, the diabetes drug market is expected to balloon from $29.81 billion in 2021 to $61.6 billion by 2030.

Insulin 98

Insulin Hormones FDA Approval Sales 98

XTalks

FEBRUARY 18, 2025

million Americans depend on insulin therapy either rapid-acting, long-acting or both to regulate their blood sugar. Insulin, a hormone produced by the pancreas, allows glucose to enter cells for energy. More than 38 million people in the US have diabetes, a condition characterized by elevated blood glucose (sugar) levels.

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Insulin FDA Approval Production Hormones 59

XTalks

NOVEMBER 15, 2021

Now, new research shows that the brain hormone serotonin may cause gut inflammation that could trigger flare-ups in Crohn’s disease. Growing evidence continues to show fundamental links between the nervous system and the gut microbiome.

Hormones 98

Hormones Regulation Research Production 98

XTalks

JULY 19, 2024

These advertisements, often found on social media platforms, search engines and various websites, frequently violate advertising guidelines and regulations. More than half a million individual ads referencing GLP-1s were monitored by LegitScript in just the last two months.

Pharmacy 104

Pharmacy Drugs Production Sales 104

XTalks

MARCH 13, 2024

Related: Transforming Eye Care: Innovating New Glaucoma and Dry Eye Disease Treatments — Featuring Pierre Simon, VP Marketing, Sight Sciences – Xtalks Life Science Podcast Ep. Hormone-based therapeutics aim to delay glaucoma progression by enhancing estrogen’s potential protective effects.

Gene Therapy 111

Gene Therapy Gene Life Science DNA 111

XTalks

JULY 2, 2021

Currently, there is no scientific evidence to suggest that the vaccines induce any hormonal changes that would lead to irregular periods. This is because the processes that maintain the uterine lining, including the placenta, during pregnancy are different than those that regulate the normal menstrual cycle.

Vaccination 105

Vaccination Vaccine Protein Immune Response 105

XTalks

JUNE 10, 2024

Efruxifermin is a novel Fc-FGF21 fusion protein designed to emulate the activity of native FGF21, an endogenous hormone that regulates metabolism and alleviates cellular stress. Numerous compounds are currently under clinical investigation for MASH. This comprehensive action of efruxifermin addresses the multifaceted nature of MASH.

Insulin 52

Insulin Life Science Regulation Hormones 52

XTalks

SEPTEMBER 17, 2020

Often, the potential patient pool for a given trial is small and the unmet need is high, incentivizing drugmakers and regulators to find innovative ways to make game-changing therapeutics available to those who need them most. Symptoms and Etiology: Caused by an overproduction of growth hormone, acromegaly primarily affects adults.

Trials 98

Trials Gene Hormones Clinical Trials 98

XTalks

APRIL 29, 2022

Tirzepatide is a novel investigational obesity treatment that contains mimetics of two hormones that are involved in regulating appetite in a single peptide: a GIP (glucose-dependent insulinotropic polypeptide) receptor agonist and a GLP-1 (glucagon-like peptide-1) receptor agonist. percent and 22.5

Trials 98

Trials Drugs FDA Approval Clinical Trials 98

XTalks

JUNE 27, 2022

The BRAF gene regulates cell growth, proliferation and apoptosis. Both Tafinlar and Mekinist target the RAS/RAF/MEK/ERK pathway , which regulates cell growth and survival; however, each affects different kinases. Tafinlar + Mekinist is also the first of its kind approved for use in pediatric patients.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Gene 52

XTalks

OCTOBER 11, 2023

They mimic the action of GLP-1, a hormone that helps regulate blood sugar levels by enhancing insulin secretion. GLP-1 agonists/inhibitors work by slowing digestion to suppress appetite but can cause problems if that process slows down too much.

Drugs 59

Drugs Insulin Hormones FDA Approval 59

XTalks

MARCH 25, 2024

They work by mimicking the action of the naturally occurring hormone GLP-1, which is involved in regulating blood sugar and appetite. GLP-1 receptor agonists, a class of drugs initially developed to treat type 2 diabetes, have been found to have significant effects on weight loss.

Drugs 105

Drugs Medicine Life Science Production 105

XTalks

NOVEMBER 9, 2023

Zepbound contains mimetics of the GLP-1 and GIP hormones that regulate appetite and blood sugar. “In light of increasing rates of both obesity and overweight in the United States, today’s approval addresses an unmet medical need.”

FDA Approval 59

FDA Approval Manufacturing Drugs Pharmacy 59

XTalks

NOVEMBER 19, 2021

Natriuretic peptides like N-terminal (NT)-pro hormone B type natriuretic peptide (NT-proBNP), or BNP, are routinely used for acute and chronic heart failure. For safety endpoints, cardiac troponin — either high sensitivity or standard — are used as markers for safety and myocardial injury and toxicity. A Functional Future State.

Clinical Trials 98

Clinical Trials Clinical Trials Trials In-Vitro 98

The Pharma Data

APRIL 11, 2023

About Bayer Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition. Bayer will present the first clinical Phase 1 results on aryl hydrocarbon receptor (AhR) inhibitor BAY 2416964, the company’s most advanced Immuno-Oncology program.

Research 40

Research Clinical Trials Clinical Trials Trials 40

XTalks

AUGUST 2, 2023

5) Ibrance (palbociclib) Ibrance is a chemotherapy drug indicated for hormone receptor positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer. It is a CDK 4/6 inhibitor that is taken in combination with other hormonal therapies to stop the growth of cancer and healthy cells. billion in 2022.

Sales 98

Sales Manufacturing FDA Approval Life Science 98

XTalks

NOVEMBER 20, 2023

AstraZeneca has won its first-in-class approval for its AKT inhibitor Truqap (capivasertib) in combination with Faslodex (fulvestrant) for treating patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer. It was also given FDA priority review.

HR 98

HR FDA Approval Gene Trials 98

XTalks

MARCH 1, 2021

And while conventional dry eye can have a number of causes — including blepharitis, hormone-related changes in post-menopausal women and contact lens use — mask-associated dry eye is largely cropping up in people who wear face masks for extended periods during the day.

Sales 119

Sales Drugs Life Science Containment 119

pharmaphorum

JUNE 8, 2022

The UK medicines regulator has awarded Alnylam’s RNAi-based therapy zilebesiran for hypertension an ‘innovation passport ‘, a designation designed to speed up NHS access to promising new medicines.

Gene Silencing 52

Gene Silencing Drugs Medicine Regulation 52

The Pharma Data

DECEMBER 9, 2020

The creation of Overland isn’t the only exciting thing happening for international life sciences companies and organizations. This work has led to the identification of molecular components regulating crucial processes impaired in depression. Below is a roundup of some of this week’s interesting news.

In-Vivo 52

In-Vivo In-Vitro Antibody Development 52

XTalks

FEBRUARY 5, 2024

In the dynamic landscape of oncology therapeutics, understanding the trends and performances of leading drugs is crucial for stakeholders across the healthcare and life sciences sectors. Zoladex is an artificial form of a hormone that regulates many processes in the body. mg implant) is around $1,006.

FDA Approval 101

FDA Approval Drugs Sales Development 101

XTalks

FEBRUARY 8, 2024

Diabetes remains a critical global challenge, affecting millions of lives and commanding significant attention from the medical, life sciences and pharmaceutical sectors. NovoMix encompasses a series of premixed insulin treatments for individuals with diabetes who require insulin to regulate their blood glucose levels.

Sales 52

Sales Insulin FDA Approval Drugs 52

XTalks

FEBRUARY 5, 2024

In the dynamic landscape of oncology therapeutics, understanding the trends and performances of leading drugs is crucial for stakeholders across the healthcare and life sciences sectors. Zoladex is an artificial form of a hormone that regulates many processes in the body. mg implant) is around $1,006.

FDA Approval 52

FDA Approval Drugs Sales Development 52

pharmaphorum

MARCH 5, 2021

Fundamental metabolic and hormonal differences can make women difficult to study compared to men but that is exactly why we must ensure we’re studying them.”. Indeed, with the pandemic shifting practices across healthcare and regulation, Maini is optimistic the disruptive forces are here to stay. “I About the interviewee.

Clinical Trials 116

Clinical Trials Clinical Trials Trials Vaccine 116

Pharmaceutical Technology

JANUARY 22, 2023

The mutation leads to disordered thyroid hormone transport, which causes patients to experience intellectual and motor disabilities. Egetis is banking on tiratricol, an oral small molecule that restores dysfunctional thyroid hormone signalling, to be the first drug approved for this condition.

Drugs 317

Drugs Gene Hormones Clinical Trials 317

XTalks

MARCH 5, 2025

In the pivotal Phase III VERIFY study, researchers evaluated rusfertide, a firstinclass investigational hepcidin mimetic peptide therapeutic designed to mimic the natural hormone that regulates iron, to see if it could reduce the need for regular blood removals (phlebotomies).

Trials 59

Trials Clinical Trials Clinical Trials Hormones 59

XTalks

MAY 20, 2022

The injection is intended to regulate blood sugar, in conjunction with diet and exercise, in adults with type 2 diabetes. Life science industry data analytics company Evaluate Vantage predicts that Mounjaro could bring in $4.9 billion in sales for Lilly by 2026. The dose is adjusted as tolerated to meet blood sugar goals.

Insulin 52

Insulin Life Science Drugs Sales 52

XTalks

JANUARY 10, 2025

Free testosterone, a key hormone involved in muscle growth, bone density and reproductive health, has been challenging to measure with precision. Each test delivers rapid results in just 48 minutes, with platforms capable of processing up to 60 samples per hour making it a powerhouse for busy labs.

Hormones 105

Hormones Antibody Clinical Trials Clinical Trials 105

XTalks

FEBRUARY 27, 2025

AstraZeneca plans to present the full dataset at an upcoming medical meeting and engage with global regulators. In the SERENA-2 Phase II trial, camizestrant improved PFS versus fulvestrant irrespective of ESR1 status or prior CDK4/6 inhibitor use, while SERENA-1 Phase I confirmed its tolerability and anti-tumor profile with CDK4/6 inhibitors.

Trials 59

Trials HR Clinical Trials Clinical Trials 59