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Neurocrine Biosciences’ Crenessity Approved as First New Treatment in Decades for Rare Genetic Disorder CAH

XTalks

CAH is a group of rare genetic disorders affecting the adrenal glands, which produce essential hormones like cortisol, aldosterone and androgens. The most common form of CAH, 21-hydroxylase deficiency, disrupts hormone production, leading to cortisol deficiency and an overproduction of androgens. billion in revenue by 2024.

Genetics 116
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Eli Lilly’s Tirzepatide Shows Promise for Keeping Prediabetic Patients Diabetes-Free

XTalks

These gut hormones are released in response to nutrient intake and play a crucial role in the incretin effect, which enhances insulin secretion. While GlobalData predicts that Mounjaro and Zepbound will contribute to GLP-1 drugs becoming the best-selling drug class this year, sales of the drugs have been slightly lower than anticipated.

Sales 105
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Roche Invests $5.3B in Zealand’s Petrelintide, an Obesity Drug Candidate

XTalks

billion, primarily linked to initiating Phase III trials for petrelintide as a stand-alone therapy, with sales-based milestones that could push the total value to $5.3 Amylin, a hormone co-secreted with insulin, plays a key role in regulating appetite by enhancing leptins effects the hormone that signals fullness after eating.

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Why Mask-Associated Dry Eye Won’t Necessarily Boost Restasis Sales

XTalks

Anti-inflammatory drugs like Restasis and Xiidra are popular treatment options for the condition, but will the emergence of mask-associated dry eye bolster their sales? But if you thought the growing number of patients presenting with mask-associated dry eye would mean higher sales for Restasis, think again.

Sales 119
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FDA Approves New Type 2 Diabetes Injection Mounjaro + US Reports First Case of Monkeypox – Xtalks Life Science Podcast Ep. 62

XTalks

In this episode, Ayesha discussed the FDA approval of Eli Lilly’s diabetes injection Mounjaro (tirzepatide) for the treatment of adults with type 2 diabetes This is a great advancement in the diabetes space as Mounjaro is a first-in-class medicine that targets the activity of two hormones involved in hunger and blood sugar control (GLP-1 and GIP).

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Povorcitinib Phase III Results Stir Mixed Signals for Incyte and Investors

XTalks

Hidradenitis suppurativa affecting roughly 1% of the population is a chronic skin condition marked by painful boils and abscesses that can significantly disrupt daily life. On March 17, 2025 , Incytes stock closed at $62.01, down 8.62% from the previous close of $67.86.

Trials 59
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New Zepbound TV Commercial Inspires ‘Change’

XTalks

Related: Eli Lillys Zepbound Approved as First Treatment for Obstructive Sleep Apnea The commercial describes Zepbounds mechanism of action as a dual receptor against that works by activating two naturally occurring hormone receptors in [the] body [GLP-1 and GIP-1]. Late last year, Zepbound brought in $1.26