The Pharma Data

JANUARY 10, 2021

We expect to further advance our late stage endocrinology pipeline with the anticipated approval and launch in the United States and the approval in Europe of TransCon hGH for pediatric growth hormone deficiency, and to obtain phase 3 results for TransCon PTH in adult hypoparathyroidism. •. ?. .

Hormones 40

Hormones Clinical Development Clinical Trials Clinical Trials 40

Pharmaceutical Technology

APRIL 24, 2023

Biologics are costly to produce and sell, and the more recent modalities, such as cell and gene therapies, can be difficult to manufacture. With new drugs on the market, companies are now looking for ways to manufacture recently approved biologics, and countries are racing to claim their corner – or maintain their decades-old market share.

Contract Manufacturing 130

Contract Manufacturing Manufacturing Protein Sales 130

Roots Analysis

SEPTEMBER 9, 2024

Over the years, pharmaceutical companies have shifted their priorities from traditional interventions towards more advanced pharmacological strategies, such as protein therapeutics. Further, $400 billion is the anticipated sales of protein-based therapeutics in 2023. The mRNA is then translated into to form functional proteins.

Protein 40

Protein Gene Production DNA 40

Camargo

NOVEMBER 29, 2021

Recombinant therapeutic proteins. Fusion proteins. They may contain proteins that control the action of other proteins and cellular processes, genes that control production of vital proteins, modified human hormones, or cells that produce substances that suppress or activate components of the immune system.

Development 180

Development Protein Production Hormones 180

XTalks

NOVEMBER 6, 2024

Gelteq’s formulations enable the delivery of various active ingredients like branched-chain amino acids, protein, caffeine and essential minerals, opening applications in sports performance, nutrition and therapeutic use.

Drug Delivery 104

Drug Delivery Drugs Bioequivalency Bioavailability 104

Pharmaceutical Technology

MAY 31, 2023

The therapeutic candidate targets immune checkpoint, programmed cell death protein 1 (PD1). Les Laboratoires Servier overview Les Laboratoires Servier (Servier) researches, develops, manufactures, and markets drugs for treating various diseases. It is administered as an intravenous infusion.

Generic Drugs 100

Generic Drugs Hormones Manufacturing Development 100

Pharmaceutical Technology

FEBRUARY 14, 2023

Alkaloids, natural dyes, drugs, proteins, and enzymes are some of the important classes of natural heterocyclic compounds essential for human life. The company filed heterocyclic composition patents in areas such as PAD4 inhibitors, factor Xa inhibitors, and nuclear hormone receptor modulators.

Antibody 130

Antibody Hormones DNA Licensing 130

Pharmaceutical Technology

MARCH 10, 2023

Pharmaceutical and biotechnology industries widely use freeze-drying systems to protect vaccines, antibodies, antibiotics such as penicillin, blood plasma, proteins, enzymes, hormones, viruses, and bacteria from heat and minimise their biological activity.

Manufacturing 147

Manufacturing Production Containment Antibody 147

The Pharma Data

OCTOBER 14, 2020

The AOP Orphan Group manufactures 80% of its drugs in Europe and has more than 20 subsidiaries and representative offices across the whole of Europe as well as in the United Arab Emirates and Israel. All jobs have been maintained and the workforce has grown from about 220 to 350. CARB-X will provide Polyphor with initial funding of up to $2.62

Clinical Trials 52

Clinical Trials Clinical Trials Manufacturing In-Vivo 52

The Pharma Data

MARCH 22, 2021

Novartis has established global expertise and specialized supply chain and manufacturing capabilities across its network of four radioligand therapy production sites, and is further increasing capacity to ensure delivery of radioligand therapies like 177 Lu-PSMA-617 to patients in need.

Hormones 52

Hormones Gene Therapy Medicine Trials 52

Roots Analysis

MARCH 21, 2022

Medical device manufacturers have developed a diverse range of products that can enable subcutaneous delivery of various injectable therapies. Many of these antibody-based products are highly viscous and need to be administered using delivery systems in volumes that exceed the standard fill of a 1 mL prefilled syringe.

Drug Delivery Systems 52

Drug Delivery Systems Drug Delivery Antibody Drugs 52

Roots Analysis

AUGUST 31, 2023

Further, the expression of any gene is dependent on the rate at which it is transcribed into mRNA and translated into proteins. There are various regulatory proteins or transcription factors that are responsible for affecting the transcription rate. When activator binds to the operon, it either speeds up or permits gene expression.

Gene 40

Gene Gene Therapy Gene Expression Regulation 40

The Pharma Data

JUNE 26, 2021

Two additional studies with 177 Lu-PSMA-617 radioligand therapy in earlier lines of treatment for metastatic prostate cancer are ongoing, investigating potential clinical utility in the mCRPC pre-taxane setting ( PSMAfore ) and in the metastatic hormone-sensitive setting ( PSMAddition ).

Medicine 52

Medicine HR Hormones Protein 52

XTalks

FEBRUARY 8, 2024

for a one-month supply Why it did so well: Jardiance belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors, inhibiting the SGLT2 protein in the kidneys to lead to the excretion of excess glucose through the urine. Jardiance brought in $2.06 billion for Eli Lilly and $6.23 billion for Boehringer Ingelheim.

Sales 52

Sales Insulin FDA Approval Drugs 52

The Pharma Data

DECEMBER 27, 2020

Proteasomes play an important role in cell function and growth by breaking down proteins that are damaged or no longer needed. i KYPROLIS has been shown to block proteasomes, leading to an excessive build-up of proteins within cells. Since its first approval in 2012, approximately 150,000 patients worldwide have received KYPROLIS.

Production 52

Production Drugs Clinical Trials Clinical Trials 52

The Pharma Data

AUGUST 3, 2021

Initial data from LUMAKRAS in combination with a mitogen-activated protein kinase kinase (MEK) inhibitor and LUMAKRAS in combination with an oral EGFR inhibitor are planned to be submitted for presentation at a Q4 2021 medical conference. Manufacturing Facilities. Tarlatamab (AMG 757). Efavaleukin alfa (AMG 592).

Sales 52

Sales Production Antibody Development 52

The Pharma Data

MARCH 17, 2021

In estrogen receptor-positive (ER+) breast cancer cell lines, cyclin D1 and CDK4 & 6 promote phosphorylation of the retinoblastoma protein (Rb), cell cycle progression, and cell proliferation. Verzenio is Lilly’s first solid oral dosage form to be made using a faster, more efficient process known as continuous manufacturing.

HR 52

HR Trials In-Vitro Manufacturing 52

The Pharma Data

APRIL 23, 2021

GSK is responsible for the ongoing research, development, commercialisation, and manufacture of each of these products under the Agreement. related adverse reactions, which may be severe or fatal, can occur in patients treated with antibodies blocking the programmed cell death protein?1 Important Information for JEMPERLI in the EU.

Antibody 40

Antibody Hormones Containment Licensing 40

XTalks

DECEMBER 22, 2021

RNA, and its protein-generating form messenger RNA (mRNA) discovered in 1961 , has quickly transitioned from being an obscure, finicky molecule that is difficult to work with, to becoming a significant cornerstone of therapeutic innovation in pharma and biotech. The RNA Revolution: From mRNA Vaccines to RNA Editing.

Life Science 98

Life Science RNA Vaccination Vaccine 98

The Pharma Data

MAY 14, 2021

It’s all based on human biology… I refer to it as your “metabolism switch”… But the scientific name for it is AMP-activated protein kinase…. Which is your #1 fat-storing hormone. Their waists got smaller… They also saw an improvement in fat-regulating hormones. How little you exercise….

Production 52

Production Insulin Packaging Packaging 52

Pfizer

JANUARY 27, 2023

Current variants of concern can be resistant to treatments that work by binding to the spike protein found on the surface of the SARS-CoV-2 virus. Contraception: Use of ritonavir may reduce the efficacy of combined hormonal contraceptives. In preclinical studies, nirmatrelvir did not demonstrate evidence of mutagenic DNA interactions.

Marketing 75

Marketing Production Drugs Licensing 75

XTalks

AUGUST 2, 2023

Most of the company’s revenue comes from the manufacture and sale of biopharmaceutical products. 5) Ibrance (palbociclib) Ibrance is a chemotherapy drug indicated for hormone receptor positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer. billion in 2022, a 23.43 billion, a 42.74 Pfizer Inc.

Sales 98

Sales Manufacturing FDA Approval Life Science 98

Pfizer

DECEMBER 20, 2022

Current variants of concern can be resistant to treatments that work by binding to the spike protein found on the surface of the SARS-CoV-2 virus. Microsomal triglyceride transfer protein inhibitor: lomitapide. Contraception: Use of ritonavir may reduce the efficacy of combined hormonal contraceptives.

Drugs 69

Drugs Licensing Licensing Containment 69

Pfizer

DECEMBER 13, 2022

Current variants of concern can be resistant to treatments that work by binding to the spike protein found on the surface of the SARS-CoV-2 virus. Microsomal triglyceride transfer protein inhibitor: lomitapide. Contraception: Use of ritonavir may reduce the efficacy of combined hormonal contraceptives.

Drugs 110

Drugs Licensing Licensing Production 110

The Pharma Data

JANUARY 4, 2021

TIGIT and PD-L1 are proteins that play a role in suppression of the immune system. Tiragolumab is a monoclonal antibody designed to bind with TIGIT, a protein receptor on immune cells. Tecentriq is a monoclonal antibody designed to bind with a protein called PD-L1. Dual blockade of the TIGIT and PD-L1 pathways. receptors. .

Medicine 52

Medicine Immune Response Protein Gene 52

The Pharma Data

FEBRUARY 8, 2021

Metastatic castration-sensitive prostate cancer, also known as metastatic hormone-sensitive prostate cancer (mHSPC), refers to prostate cancer that still responds to hormonal therapy and has spread beyond the prostate to other parts of the body. [4]. About Metastatic Castration-Sensitive Prostate Cancer. About ERLEADA ® (apalutamide).

HR 52

HR Hormones Development Production 52

Pfizer

NOVEMBER 23, 2022

Europe plays a critical role in the delivery of PAXLOVID to patients across the globe, as the site of four of Pfizer’s key PAXLOVID manufacturing facilities. Current variants of concern can be resistant to treatments that work by binding to the spike protein found on the surface of the SARS-CoV-2 virus. Immunosuppressants: voclosporin.

Licensing 40

Licensing Licensing Drugs Manufacturing 40

The Pharma Data

FEBRUARY 8, 2021

Hypothyroidism — In 2 randomized studies, hypothyroidism was reported for 8% of patients treated with ERLEADA ® and 2% of patients treated with placebo based on assessments of thyroid-stimulating hormone (TSH) every 4 months. The safety profile was consistent with prior studies of ERLEADA ® , with no new safety signals observed.

HR 52

HR In-Vitro Development Clinical Trials 52

Pfizer

JANUARY 27, 2023

Working with collaborators, we have conducted research where the original SARS-CoV-2 virus has been used to express the spike protein from new variants of concern. Contraception: Use of ritonavir may reduce the efficacy of combined hormonal contraceptives.

Research 112

Research Vaccination Vaccine Drugs 112

The Pharma Data

MAY 4, 2021

Following the completion of the spin-off of the Upjohn Business (4) in the fourth quarter of 2020, Pfizer now operates as a focused innovative biopharmaceutical company engaged in the discovery, development, manufacturing, marketing, sales and distribution of biopharmaceutical products worldwide. down 7%, which reflects relatively stable U.S.

Vaccination 40

Vaccination Vaccine Production Sales 40