Scienmag

MAY 17, 2021

Revelations from a fly study could improve our understanding of protein malnutrition in humans.

Protein 52

Protein Hormones Research Engineer 52

pharmaphorum

JULY 22, 2021

Pfizer has pledged a whopping $1 billion upfront for rights to an Arvinas drug for breast cancer from its protein degrader platform, which harnesses cells’ natural protein-denaturing machinery to remove rogue proteins associated with disease.

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Protein Hormones Bioavailability Drugs 116

Pharmaceutical Technology

JANUARY 22, 2023

The mutation leads to disordered thyroid hormone transport, which causes patients to experience intellectual and motor disabilities. Egetis is banking on tiratricol, an oral small molecule that restores dysfunctional thyroid hormone signalling, to be the first drug approved for this condition.

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Drugs Gene Hormones Clinical Trials 317

Pharmaceutical Technology

SEPTEMBER 26, 2022

The 'life-extending' drug combination is recommended for usage in adult patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancer who have previously received hormone therapy. It acts by hindering proteins in cancer cells to avert cell division and growth.

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HR Drugs Hormones Medicine 130

XTalks

JANUARY 24, 2022

Fooditive Group , a plant-based ingredient manufacturer, recently developed a vegan version of casein, one of the main animal proteins in milk. In developing the vegan casein, Fooditive aims to eradicate the downsides of factory farming, antibiotics, hormones and lactose. So, what is casein?

Gene Splicing 112

Gene Splicing Protein Hormones Production 112

Roots Analysis

MAY 21, 2024

Proteins are the chains of amino acids linked together in different combinations and perform a wide variety of functions. However, continuous regulation of the cellular proteome is essential for maintaining the right balance of different proteins necessary for normal cellular function, survival, and proliferation.

Protein 40

Protein Marketing Development Antibody 40

Pharmaceutical Technology

APRIL 11, 2023

Veneno will carry out a programme to generate functional peptides (DRPs) for G protein-coupled receptors (GPCRs), which will be targeted by Astellas. GPCRs, which secure extracellular neurotransmitters and hormones and transfer their signals to the inside of the cell, are engaged in maintaining homeostasis inside and outside the cell.

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Research Bacteria Hormones Protein 130

XTalks

AUGUST 27, 2021

Renegade Creamery makes plant-based cheese but adds milk proteins produced in strains of yeast and bacteria and uses an “artisan fermentation process.” Like Renegade Creamery, the company also uses transgenic bacteria and yeast to make the protein because they have a history of being a safe and reliable way of producing animal proteins.

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Production Protein Containment Branding 98

Medical Xpress

DECEMBER 12, 2022

Ana Guadaño at the Alberto Sols Biomedical Research Institute (IIBM, a combined CSIC-UAM center) and involving the Complutense University of Madrid (UCM), used CRISPR gene editing techniques to incorporate into mice a mutation of the MCT8 protein responsible for transporting thyroid hormones to the interior of the cell.

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Gene Editing Genetics Hormones Medicine 75

XTalks

MARCH 18, 2025

Standard treatment strategies include combinations of antibiotics, hormonal therapies and biologic agents most notably adalimumab (Humira), the only FDA-approved biologic for moderate to severe cases while surgery remains an option for advanced disease.

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Trials Clinical Trials Clinical Trials Hormones 59

Scienmag

FEBRUARY 12, 2021

Among the markers now in use are genes, proteins, hormones, lipids and other classes of molecules. Biomarkers play a central role in the diagnosis of disease and assessment of its course. Biomarkers can be found in the blood, in cerebrospinal fluid, urine and various types of tissues, but most of them have one thing in […].

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Hormones Protein Gene 68

Trialfacts

NOVEMBER 30, 2023

Not all proteins are created equal when it comes to muscle growth. Join researchers on this exciting journey to discover how the right combination of exercise and a specific plant-based protein blend can help you regain your muscle as you age. Explore the Power of Plant-Based Proteins for Active Aging appeared first on Trialfacts.

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Protein Research Hormones Containment 52

The Pharma Data

JULY 22, 2021

NYSE: PFE) today announced a global collaboration to develop and commercialize ARV-471, an investigational oral PROTAC® (PROteolysis TArgeting Chimera) estrogen receptor protein degrader. ER is the primary driver of hormone receptor (HR) positive breast cancer, which is the most common breast cancer subtype.

Protein 52

Protein Development HR Hormones 52

Scienmag

SEPTEMBER 15, 2020

Researchers develop a wider spectrum for dLight1 sensor, allowing multiplex imaging of neurotransmitters Credit: UC Regents Sacramento, CA– In 2018, Lin Tian and her team at UC Davis Health developed dLight1, a single fluorescent protein-based biosensor.

Hormones 55

Hormones Protein Development Research 55

XTalks

JANUARY 31, 2022

By using analytical chemistry to identify key flavor compounds found in animal-based meat, the San-Francisco-based startup structured the compounds around plant-based proteins composed mainly of pea protein. It also contains sunflower oil, refined coconut oil and cocoa butter.

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Branding Protein Containment Production 98

XTalks

MARCH 7, 2024

Optimizing Sleep During Perimenopause and Beyond Sleep plays a crucial role in overall health, particularly for midlife women transitioning into menopause, a phase marked by perimenopause where hormonal changes can severely disrupt sleep due to symptoms like nocturnal hot flashes.

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Genetics Hormones Genome Genomics 115

XTalks

NOVEMBER 2, 2021

The test measures levels of C-peptide protein in the blood, which is a byproduct of insulin synthesis that is released from the pancreas along with the hormone. Moreover, current ultrasensitive C-peptide assays can detect levels of the protein in very low ranges of 0.0015–0.0025 nmol/L.

Insulin 98

Insulin Protein Hormones Regulation 98

XTalks

JULY 2, 2021

Currently, there is no scientific evidence to suggest that the vaccines induce any hormonal changes that would lead to irregular periods. However, the similarity between the two proteins is not great enough for anti-spike antibodies to cross-react with placental syncytin-1.

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Vaccination Vaccine Protein Immune Response 105

XTalks

JANUARY 3, 2024

Perdue celebrated this launch with a special “ Ultimate at Home Wing Kit ,” showcasing its commitment to antibiotic-, hormone- and steroid-free chicken, raised cage-free on a vegetarian diet. These high-protein, low-sugar bars offer a portable and keto-friendly snack option.

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Production Protein Hormones Packaging 103

XTalks

JANUARY 23, 2024

Pediatric growth hormone deficiency (PGHD) is one such condition, affecting a child’s growth and development. This rare endocrine disorder, characterized by inadequate secretion of growth hormone from the pituitary gland, has profound impacts on physical and sometimes cognitive development.

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Development Hormones Drugs Trials 72

XTalks

NOVEMBER 5, 2024

a clinical-stage biotech company focused on pioneering therapies based on G protein-coupled receptors (GPCRs), recently completed its initial public offering (IPO), marking a significant milestone for the South San Francisco-based firm. SEP-786, an oral parathyroid hormone 1 receptor (PTH1R) agonist, aims to restore essential mineral balance.

Drugs 59

Drugs Hormones Protein Antibody 59

The Pharma Data

DECEMBER 9, 2020

The trial, conducted in nine countries, found that adding chemotherapy to hormone-blocking drugs brought no added benefit to a particular group of patients. Those were postmenopausal women with hormone-sensitive breast cancer that had spread to only one to three lymph nodes, and who had a low risk of recurrence. WEDNESDAY, Dec.

Hormones 52

Hormones Trials Medicine Research 52

XTalks

SEPTEMBER 17, 2020

Symptoms and Etiology: Caused by an overproduction of growth hormone, acromegaly primarily affects adults. By reducing the amount of growth hormone in the blood, progressive enlargement of bones should be slowed. By reducing the amount of growth hormone in the blood, progressive enlargement of bones should be slowed.

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Trials Gene Hormones Clinical Trials 98

Pharmaceutical Technology

MARCH 23, 2023

Hormonal contraceptives, and other drugs like clomiphene, eflornithine have been reported to ameliorate symptoms. While the number of new investigational therapies specifically designed to treat PCOS is scant, some companies continue to repurpose hormonal medications. The study’s results are anticipated for release in mid-2023.

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Development Insulin Hormones Research 130

pharmaphorum

SEPTEMBER 14, 2020

The drug zeroes in on cancer cells expressing a protein known as LIV-1 and is in phase 1 development for breast cancer and other solid tumours. MSD will be responsible for ex-US filings including Europe and will record sales outside the US, Europe, and Canada.

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Genetics Development Drugs Protein 52

The Pharma Data

NOVEMBER 2, 2020

That’s one finding from an early study that tested the injection drug, which mimics the effects of a natural hormone called fibroblast growth factor 21 (FGF21). FGF21 is a hormone that helps control metabolism by stimulating certain receptors in fat tissue, the liver, the pancreas and the central nervous system. MONDAY, Nov.

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Antibody Drugs Hormones Insulin 52

Delveinsight

JULY 30, 2020

Adrenoleukodystrophy (ALD/ X-ALD) is a rare, X-linked disorder secondary to a mutation in the ABCD1 gene, which encodes for a peroxisomal membrane protein, resulting in an excessive accumulation of very-long-chain fatty acids (VLCFAs) in the brain and adrenal glands. The disorder can occur at any stage of life and vary with severity.

Hormones 52

Hormones Marketing Gene Trials 52

Trialfacts

NOVEMBER 22, 2022

In this study, researchers want to see how different markers (such as hormones and proteins) in your blood and muscle, respond to physical activity and recovery. You can experience these periods of muscle rest due to healing time after surgery, illness, rehab, or injury. .

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Research Hormones Protein 52

XTalks

SEPTEMBER 28, 2023

Parabens, which are also prevalent in cosmetics, can interfere with the regular operation of human hormonal systems, affecting both male and female reproductive health, development, fertility and birth results. There’s been varied research regarding the synthetic hormone’s association with breast cancer.

Hormones 52

Hormones Containment Production Cosmetics 52

XTalks

JULY 13, 2021

Additionally, per serving, they have 14 grams of protein, made mostly of fava bean, and have 40 percent less saturated fat than other tenders on the market. The plant-based tenders are free of GMOs, antibiotics, and hormones. They are breaded, tender and great for a quick snack or even a lunchtime meal.

Protein 52

Protein Marketing Production Hormones 52

The Pharma Data

JANUARY 7, 2021

He also noted innovations are occurring with protein degraders, antibody conjugates, nanobodies and multi-specific antibodies, specifically bi- and tri-specific. That platform will allow the company to engineer new proteins, Nestle said. To meet that goal, Sanofi is investing in areas like synthetic biology and cell and gene therapy.

Protein 52

Protein Antibody Genetics Gene Therapy 52

Roots Analysis

OCTOBER 24, 2023

This has led to their widespread production and extensive use in the treatment of various indications including hormonal imbalances, oncological disorders and respiratory disorders. The ADCs bind to specific proteins or peptides in cancer cells with very high specificity and efficacy influencing the biological functions.

Manufacturing 40

Manufacturing Hormones Contamination Containment 40

Delveinsight

DECEMBER 7, 2020

The test identifies Ubiquitin and Glial Fibrillary Acidic Protein (GFAP)- 2 brain-specific protein biomarkers- that appear rapidly in the blood of a patient after a brain injury. The device can be configured to inject a specific dose of the hormones into the patient.

Protein 56

Protein Insulin Development Hormones 56

XTalks

MARCH 13, 2024

Hormone-based therapeutics aim to delay glaucoma progression by enhancing estrogen’s potential protective effects. Immunotherapies, which are at an early stage of development for glaucoma, have the potential to correct immune system anomalies associated with glaucoma.

Gene Therapy 111

Gene Therapy Gene Life Science DNA 111

XTalks

SEPTEMBER 15, 2020

In addition to the vaccine, the company is also developing an investigational drug called Remygen for the regeneration of endogenous insulin production and to improve hormonal response to hypoglycemia; trials to test the treatment are currently ongoing in patients that have been living with type 1 diabetes for more than five years.

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Vaccine Vaccination Insulin Trials 103

Find Me Cure

OCTOBER 13, 2019

CDK4/6 inhibitors are used alongside hormone therapy. HER2 is a protein that plays an important role in cancer cell growth and is found on the surface of cancer cells in a very high quantity in about 10-20% of breast cancers. Then they checked which of her TILs would recognize the mutated proteins.

Development 52

Development DNA Clinical Trials Clinical Trials 52

Delveinsight

JANUARY 7, 2021

It also slates to commence a Phase Ib trial of its second candidate, TERN-201, a vascular adhesion protein (VAP-1) inhibitor, with top-line data anticipated in the first half of 2022. Terns schedules to bring a third candidate into the clinic this year, TERN-501, a thyroid hormone receptor (THR) beta-agonist.

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RNA Clinical Trials Clinical Trials Bioavailability 52