Scienmag

JUNE 21, 2022

Diabetes is a lifelong, chronic health condition caused by abnormalities in the body’s production and use of the hormone insulin. Research has shown that the feel-good hormone, dopamine (DA), plays a key role in how the body regulates the production of insulin.

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XTalks

SEPTEMBER 24, 2020

Some of these chemicals are known endocrine (hormone) disruptors linked to developmental, cognitive and other health problems in babies and adults. In terms of the potential harms of food additives and packaging, synthetic chemicals that affect hormones have additive or synergistic effects.

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Regulation Hormones Containment Packaging 94

Pharmaceutical Technology

JUNE 13, 2023

The combination therapy is intended to treat hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer in adult patients, after recurrence or progression on or after an endocrine-based regimen. AstraZeneca stated that its NDA is being reviewed under Project Orbis.

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Scienmag

DECEMBER 10, 2021

Use of certain personal care products during pregnancy may impact maternal hormone levels, according to a new Rutgers study. These chemicals interact with hormone systems, influencing synthesis, regulation, transport, […].

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Hormones Production Containment Regulation 63

Scienmag

APRIL 13, 2021

Cortisol, a steroid hormone commonly known as the “stress hormone,” plays a significant role in the regulation of a range of […]. The paper was published in the journal Talanta.

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Hormones Regulation Development Research 59

Scienmag

OCTOBER 21, 2020

Low levels of key, body-regulating chemicals in mothers during the first three months of pregnancy may interfere with the baby’s brain development, a large American study shows. These chemicals, or hormones, are produced in the thyroid gland in the neck and are known to influence fetal growth.

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Hormones Regulation Production Development 66

BioTech 365

OCTOBER 6, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: The plant hormone auxin may promote disease by regulating virulence gene expression.Scientists have long known that the plant hormone auxin controls many aspects of plant growth, development, … Continue reading →

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XTalks

MARCH 19, 2025

Eneboparatide (AZP-3601), an investigational parathyroid hormone 1 receptor (PTH1R) agonist, met its primary endpoint in the CALYPSO Phase III trial, offering new data for adults with chronic hypoparathyroidism. AstraZeneca received eneboparatide during its $1.05 Without proper PTH function, patients may face kidney and bone complications.

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Trials Hormones Engineer Licensing 59

Antidote

JUNE 16, 2023

They also are responsible for producing hormones and regulating various salts and minerals that are necessary for bodily functions. Despite being relatively small organs, the kidneys are extremely important to the functioning of the human body. Their main function is to filter the blood, eliminating wastes, toxins, and excess fluids.

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XTalks

MARCH 17, 2025

Amylin, a hormone co-secreted with insulin, plays a key role in regulating appetite by enhancing leptins effects the hormone that signals fullness after eating. Petrelintide, Zealand Pharmas long-acting amylin analog, is currently in Phase II clinical development and is designed for once-weekly subcutaneous injections.

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Scienmag

JANUARY 19, 2022

Seeking to better understand the key role the female hormone estrogen plays in maintaining energy balance and weight control, a group led by researchers at Baylor College of Medicine looked into estrogen interactions with specific brain regions that provide these anti-obesity benefits.

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Regulation Research Hormones Medicine 64

XTalks

FEBRUARY 5, 2025

a clinical-stage biotech company focused on developing next-gen injectable and oral nutrient-stimulated hormone (NuSH) analog peptides for the treatment of obesity, overweight and related conditions, has priced its initial public offering (IPO) at $18.00 Metsera, Inc., per share, raising $275 million in gross proceeds.

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Hormones Bioavailability Clinical Trials Clinical Trials 59

XTalks

FEBRUARY 21, 2025

Related: Obesity-Focused Metsera Launches IPO Amid Much Anticipation Aardvarks approach centers on developing novel, small-molecule drugs that harness the bodys natural hunger-regulating mechanisms. In the gut, these receptors prompt the release of hormones such as cholecystokinin and GLP-1, which together signal satiety.

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Genetics Hormones Gene Expression Gene 59

BioTech 365

SEPTEMBER 18, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Yeast and bacteria together biosynthesize plant hormones for weed control.Plants regulate their growth and development using hormones, including a group called strigolactones that prevent excessive budding and … Continue (..)

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Outsourcing Pharma

APRIL 24, 2024

revealed that XTANDITM (enzalutamide) has received a label extension from the European Commission, marking it as the inaugural and only novel hormone therapy endorsed for high-risk biochemical recurrent non-metastatic hormone-sensitive prostate cancer (nmHSPC) treatment in the European Union (EU).

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Hormones Drugs Regulation Marketing 91

pharmaphorum

JANUARY 17, 2022

Under the joint research plan, the Danish giant will work with EraCal to identify novel drug targets relevant for food intake regulation and additional metabolic phenotypes. Securing FDA approval was a huge development for the obesity space, marking the first approval for a weight management drug to be granted by the regulator since 2014.

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pharmaphorum

MARCH 23, 2021

The company said it plans to present data at an upcoming medical meeting and will include it in filings with the FDA and regulators in Europe. In castration resistant prostate cancer (CRPC), the tumour shows signs of growth, such as rising Prostate Specific Antigen (PSA) levels, despite the use of hormone treatments that lower testosterone.

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Pharmaceutical Technology

APRIL 14, 2023

The regulator has issued a complete response letter. Along with endocrine therapy, Verzenio received approval as an adjuvant treatment for hormone receptor-positive, human epidermal growth factor receptor 2-negative, node-positive early breast cancer adult patients at a high recurrence risk.

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Manufacturing Drugs Hormones Packaging 130

Worldwide Clinical Trials

JULY 8, 2024

Individuals with familial cancer syndrome may have inherited mutations that predispose them to cancer development, affecting genes involved in DNA repair and cell cycle regulation. Hormonal Status : A body’s hormones, such as levels of reproductive hormones and thyroid function, can impact tissue responses to radiation therapy.

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XTalks

JANUARY 9, 2024

The thyroid plays a critical role in the body by producing hormones that regulate metabolism, heart rate and body temperature among others. Types of Thyroid Conditions There are several different thyroid conditions, with each affecting thyroid hormone production or the gland’s structure, leading to a range of health issues.

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BioPharma Reporter

SEPTEMBER 19, 2024

Novartis announced this week that the FDA has approved ribociclib (marketed as Kisqali) for the treatment of people with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR-positive, HER2-negative) stage two or three early breast cancer, who are at high risk of cancer recurrence.

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Medical Xpress

FEBRUARY 23, 2023

Type 2 diabetes is a chronic disease in which the body does not produce enough of the hormone insulin, which regulates blood sugar, while cells in the muscle, fat and digestive system simultaneously become less sensitive to it, absorbing less sugar from the blood stream.

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Pharmaceutical Technology

OCTOBER 13, 2022

Melatonin has a prescription-only status and is strictly regulated in the UK, making this the first time it has been approved for use in this indication. The hormone is produced endogenously in the body by the pineal gland. The therapeutic is meant for youth with ADHD aged 6-17 years who found sleep hygiene measures inadequate.

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XTalks

NOVEMBER 26, 2020

In addition to innovative new antibody drugs and mRNA vaccines, researchers have found that the sleep-regulating hormone melatonin may also offer protection against COVID-19. Melatonin, which regulates the body’s circadian rhythm and sleep-wake cycle, is also available in pill form for use as a sleep aid.

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XTalks

DECEMBER 13, 2024

Petrelintide, administered once a week under the skin, targets obesity through its action as an amylin analog, a hormone co-secreted with insulin from the pancreas. Amylin helps regulate satiety and slows gastric emptying, which can support weight loss.

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ProRelix Research

SEPTEMBER 26, 2023

Endocrine disorders result from the improper functioning of endocrine glands that secrete and regulate hormones responsible for functioning of various organs.

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Scienmag

JANUARY 26, 2021

Hormone treatment can help reduce cysts in fruit fly renal tubules, according to Cassandra Millet-Boureima and Chiara Gamberi Credit: Concordia University A hormone commonly associated with sleep-wake regulation has been found to reduce cysts in fruit flies, according to Concordia researchers.

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XTalks

NOVEMBER 9, 2022

GLP-1 receptor agonists, or incretin (metabolic hormones) mimetics, are analogs of the GLP-1 peptide hormone that binds to the GLP-1 receptor to regulate blood sugar levels by boosting insulin secretion. Accordingly, the diabetes drug market is expected to balloon from $29.81 billion in 2021 to $61.6 billion by 2030.

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Pharmaceutical Technology

MARCH 10, 2023

Pharmaceutical and biotechnology industries widely use freeze-drying systems to protect vaccines, antibodies, antibiotics such as penicillin, blood plasma, proteins, enzymes, hormones, viruses, and bacteria from heat and minimise their biological activity.

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pharmaphorum

AUGUST 16, 2022

The US regulator has started a priority review of Lynparza (olaparib) in combination with abiraterone and prednisone or prednisolone as a first-line treatment for metastatic castration-resistant prostate cancer (mCRPC) based on the results of the PROpel trial. months and 16.6 months, respectively.

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pharmaphorum

AUGUST 15, 2022

At this year’s ASCO congress, the Trop2-targeting antibody-drug conjugate (ADC) was found to improve progression-free survival significantly in in patients with hormone receptor-positive, HER2-negative metastatic breast cancer who received multiple lines of prior treatment.

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XTalks

FEBRUARY 18, 2025

million Americans depend on insulin therapy either rapid-acting, long-acting or both to regulate their blood sugar. Insulin, a hormone produced by the pancreas, allows glucose to enter cells for energy. More than 38 million people in the US have diabetes, a condition characterized by elevated blood glucose (sugar) levels.

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XTalks

NOVEMBER 15, 2021

Now, new research shows that the brain hormone serotonin may cause gut inflammation that could trigger flare-ups in Crohn’s disease. Growing evidence continues to show fundamental links between the nervous system and the gut microbiome.

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Pharmaceutical Technology

FEBRUARY 24, 2023

Douglas provides products in various therapeutic areas which include psoriasis, eczema, dermatitis, chicken pox, constipation, laxative, neonatal, hormone regulation, dermatology, cardiovascular and measles, among others. Its investigational medicinal products comprise R-107, R-131 and R-147.

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Pharmaceutical Technology

FEBRUARY 24, 2023

Douglas provides products in various therapeutic areas which include psoriasis, eczema, dermatitis, chicken pox, constipation, laxative, neonatal, hormone regulation, dermatology, cardiovascular and measles, among others. Its investigational medicinal products comprise R-107, R-131 and R-147.

Contract Manufacturing 100

Contract Manufacturing Dermatology Hormones Production 100

Scienmag

MARCH 29, 2021

No FDA regulations in place to alert patients when medication is derived from animals More physicians and pharmacists are advocating for patients to be made aware of animal byproducts contained in common medications, according to new research in the Journal of Osteopathic Medicine.

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Scienmag

DECEMBER 8, 2020

In an article published in the Journal of Pineal Research, researchers at São Paulo State University and collaborators describe a set of genes potentially regulated by the ‘sleep hormone’ in some types of tumor A Brazilian study published in the Journal of Pineal Research describes a group of genes potentially regulated by the hormone melatonin (..)

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