Pharmaceutical Technology

NOVEMBER 16, 2022

Under the deal, the LentiPeak lentiviral vector technology platform and cell therapy production expertise of ElevateBio BaseCamp will be used by Affini-T to develop its investigational oncogenic driver programmes in the clinic.

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Pharmaceutical Technology

SEPTEMBER 14, 2022

As an autologous cell therapy, manufacturing the infusion product is a highly specialised process involving tumour harvest and the extraction and large-scale ex vivo expansion of TILs. The use of engineered immune cytokines that selectively induce the expansion of TILs is being investigated as an alternative to IL-2 stimulation.

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Immune Response In-Vivo Production Manufacturing 246

Pharmaceutical Technology

NOVEMBER 11, 2022

The latest development comes after the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) provided a positive opinion on vaccine use. The vaccine elicited a robust immune response against several variants in registrational trials conducted when the Omicron variant of the virus was dominant.

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Pharmaceutical Technology

MAY 25, 2023

The results from a trial, published in The New England Journal of Medicine , found the vaccine was associated with a strong immune response and good safety profile. The response was more powerful than that generated by MenACWY-D – a licensed quadrivalent meningococcal vaccine marketed by GSK.

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Vaccine Vaccination Immune Response Bacteria 195

Pharmaceutical Technology

JUNE 10, 2023

Influenza vaccine 2 is under clinical development by Shanghai Institute of Biological Products and currently in Phase I for Pandemic Influenza. The vaccine works by inducing the body's immune response. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Influenza vaccine 2 LoA Report.

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Production Vaccine Vaccination Immune Response 100

Pharmaceutical Technology

JUNE 10, 2023

Influenza vaccine 2 is under clinical development by Shanghai Institute of Biological Products and currently in Phase I for Pandemic Influenza. The vaccine works by inducing the body's immune response. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Influenza vaccine 2 LoA Report.

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Production Vaccine Vaccination Immune Response 100

XTalks

FEBRUARY 5, 2025

The FDAs decision was based on comprehensive data demonstrating biosimilarity between Avtozma and the reference product, Actemra. Avtozma will be available in the same formulations and dosages as the reference product. It also has EUA for children aged between two and 18. The SC injection comes in 162 mg/0.9

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BioTech 365

JANUARY 10, 2022

MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed BV® test recently … Continue reading →

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BioTech 365

JANUARY 10, 2022

MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed BV® test recently … Continue reading →

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Immune Response Production 40

BioTech 365

JANUARY 10, 2022

MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed raises $93M to accelerate commercialization of its host immune-response product portfolio MeMed BV® test recently … Continue reading →

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Immune Response Production 40

BioPharma Reporter

MAY 25, 2021

An experimental recombinant protein nanoparticle vaccine that stimulates a strong immune response is hoping to address that inefficiency. Seasonal flu vaccines typically work 40-60% of the time, according to the US Centers for Disease Control and Prevention (CDC).

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Vaccine Vaccination Immune Response Production 91

World of DTC Marketing

DECEMBER 29, 2020

First, a novel approach was used that didn’t require traditional vaccine production in cell cultures or eggs. Once introduced into the human body, the protein-making machinery uses this genetic material in our cells to churn out the coronavirus “spike protein,” triggering an immune response.

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Vaccine Vaccination Development Clinical Trials 307

Medical Xpress

JANUARY 17, 2025

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts.

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Immune Response Production 98

Medical Xpress

MAY 10, 2023

SLFN 12 shuts down viral protein production and helps virus-infected cells to escape from anti-HIV therapy and immune responses. These findings pave the way for improving therapeutic strategies that aim to cure HIV infections.

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Immune Response Protein Production Research 109

Medical Xpress

FEBRUARY 15, 2023

Researchers from Japan have found that white blood cells, known as B lymphocytes, have a pivotal role in promoting an emergent response to stimulate the in-demand production of innate immune cells during an infection.

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Immune Response Production Research 75

Scienmag

JUNE 2, 2021

When pigs get hit with significant illnesses during key stages of pregnancy, their immune response may negatively affect developing piglets, making them less productive on the farm. Credit: University of Illinois URBANA, Ill.

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Immune Response Production Development Research 98

Pharmaceutical Technology

AUGUST 15, 2022

The UK Medicines and Healthcare products Regulatory Agency (MHRA) has granted conditional authorisation for Moderna ’s Covid-19 booster vaccine, mRNA-1273.214 (Spikevax Bivalent Original/Omicron), for use in adults aged 18 years and above. 1 variant as well as the original 2020 strain.”.

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Pharmaceutical Technology

MARCH 20, 2023

The collaboration, under a sponsored research agreement, will focus on mRNA vaccines that can help in modulating the normal immune response of the body for the treatment of certain autoimmune diseases as well as allergic conditions.

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Vaccine Vaccination Development Allergies 245

The Pharma Data

AUGUST 16, 2021

Better activation of innate and adaptive immune responses was achieved with CV2CoV, resulting in faster response onset, higher titers of antibodies, and stronger memory B and T cell activation as compared to the first-generation candidate, CVnCoV. “In Induction of innate immunity was investigated via specific cytokine markers.

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Immune Response Vaccination Vaccine Antibody 52

Camargo

JULY 27, 2021

It is a comprehensive term which encompasses a large variety of therapy products including viral and bacterial vectors, plasmid DNA, human gene editing technology, and patient-specific cellular gene therapy. Gene Therapy Definition. Gene therapy is a new therapeutic approach in which genes are used to treat or prevent diseases.

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Gene Therapy Gene Gene Editing Genetics 238

Camargo

DECEMBER 13, 2021

The development of biological products (or biologics) represents a major advancement in modern medicine, enabling the treatment of patients with many illnesses where no other therapeutics were previously available. The regulations regarding BLAs for therapeutic biological products are included in 21 CFR parts 600 , 601 , and 610.

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Pharmaceutical Technology

JUNE 30, 2022

This technology can stimulate an immune response with a dose up to 20 times lower than current vaccines, which enhances safety, lowers costs, and increases production speed. . At present, the vaccine is being analysed in clinical trials in the US, Brazil and South Korea.

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Pharmaceutical Technology

JULY 25, 2022

The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended an update to the conditional marketing authorization (CMA) to include Moderna ’s 50µg booster dose of Covid-19 vaccine, Spikevax, for usage in adolescents aged 12 to 17 years.

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Immune Response Vaccine Vaccination Medicine 147

XTalks

OCTOBER 24, 2024

AX-158 offers a new class of therapy, by targeting immune responses without causing immunosuppression, making it a potentially safer option for long-term treatment, with results expected by the end of 2024.

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Research Dermatology Clinical Trials Clinical Trials 105

pharmaphorum

JULY 6, 2021

While these types of tests are important, they don’t tell the whole story, as they can’t provide information on whether an individual has built an immune response to COVID-19, either through vaccination or through a previous infection. This is where antibody tests come in. The Importance of Antibody Certificates.

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Antibody Immune Response Protein Vaccine 111

Scienmag

MAY 26, 2021

In series of samples collected from individuals vaccinated against COVID-19, an ultrasensitive test detected low concentrations of circulating antigen; Following robust production of antibodies, viral protein declined to undetectable levels The carefully orchestrated dance between the immune system and the viral proteins that induce immunity against (..)

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Immune Response Protein Vaccine Vaccination 54

XTalks

DECEMBER 30, 2024

SLE is an autoimmune disease where the immune system attacks healthy tissues, causing inflammation, pain and potential organ damage. Cenerimod modulates the immune response, reducing inflammation and preventing the production of harmful autoantibodies.

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Immune Response Gene Expression Drugs Trials 52

Pharmaceutical Technology

JULY 18, 2022

In clinical trials, the adjuvanted formulation induced the necessary immune response using a reduced amount of antigen versus a formulation without adjuvant, indicating that more doses could be available during a pandemic. H1N1, also called Swine Flu is the latest influenza pandemic in the country.

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Vaccine Vaccination Immune Response Clinical Trials 162

pharmaphorum

JULY 27, 2022

The vaccine, codenamed BNT162b5, codes for “enhanced” prefusion spike proteins from the original wild-type strain of the virus and the Omicron variant that are designed to increase “the magnitude and breadth of the immune response.” Clinical data show strong neutralising antibody responses against Omicron BA.1,

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Protein Immune Response Vaccination Vaccine 122

The Pharma Data

JULY 29, 2021

Loxo Oncology at Lilly, a research and development group of Eli Lilly and Company (NYSE: LLY), and Kumquat Biosciences today announced an exclusive collaboration focused on the discovery, development and commercialization of potential novel small molecules that stimulate tumor-specific immune responses.

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Immune Response Development Medicine Drugs 52

Pharmaceutical Technology

MAY 17, 2023

It has been designed for controlling the complement factor C5a, which is a protein that plays an important and harmful role in the immune response of the body. Together, we will now ramp up production under high pressure to roll out supply in order to serve the patient population in need as soon as possible.

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Manufacturing Immune Response Protein Antibody 130

Pharmaceutical Technology

MAY 10, 2023

Gilead Sciences research executive vice-president Flavius Martin stated: “The team at XinThera has developed research assets with the potential to target the DNA damage repair pathway in treating cancer and direct the body’s immune response in inflammatory diseases, both of which may improve outcomes for people living with these diseases.

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Immune Response DNA Clinical Trials Clinical Trials 130

Scienmag

MARCH 25, 2021

Cell Stem Cell, 2021, HOUSTON, TX – March 25, 2021 – Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections. Credit: Hormaechea-Agulla et al.,

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Immune Response Production Allergies Medicine 52

XTalks

NOVEMBER 12, 2024

Adjunctive Therapies Using Immune Modulators Immune modulators, which help to regulate the body’s immune response, are increasingly recognized as supportive treatments for pneumonia. These therapies work by controlling excessive inflammatory responses in the lungs.

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Bacteria Life Science Vaccine Vaccination 110

Pharmaceutical Technology

JANUARY 19, 2023

The findings showed that the Nuvaxovid booster dose increased immune responses compared to higher levels associated with the protection in Phase III clinical trials. Nuvaxovid demonstrated a significant antibody response when given as a booster dose after primary vaccination with other authorised Covid-19 doses in the COV-BOOST trial.

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Vaccine Vaccination Immune Response Protein 147

Pharmaceutical Technology

JUNE 16, 2023

Avenge Bio is a biotechnology company developing cell-based immunotherapeutic products to treat intractable solid tumours by leveraging its LOCOcyte platform, an allogeneic cell-based immunotherapy platform that facilitates the local modulation of the immune system.

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Drugs Immune Response Clinical Development Trials 130

Pharmaceutical Technology

DECEMBER 6, 2022

Evaxion CEO Per Norlén said: “We believe that ExpreS 2 ion´s superb platforms for the production of complex proteins are a great match with our AI platform for target discovery and our novel technologies for inducing strong immune responses.

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