Pharmaceutical Technology

JUNE 10, 2023

Influenza vaccine 2 is under clinical development by Shanghai Institute of Biological Products and currently in Phase I for Pandemic Influenza. The vaccine works by inducing the body's immune response. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Influenza vaccine 2 LoA Report.

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Pharmaceutical Technology

JUNE 10, 2023

Influenza vaccine 2 is under clinical development by Shanghai Institute of Biological Products and currently in Phase I for Pandemic Influenza. The vaccine works by inducing the body's immune response. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Influenza vaccine 2 LoA Report.

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Production Vaccination Vaccine Immune Response 100

XTalks

FEBRUARY 5, 2025

The FDAs decision was based on comprehensive data demonstrating biosimilarity between Avtozma and the reference product, Actemra. Avtozma will be available in the same formulations and dosages as the reference product. It also has EUA for children aged between two and 18. The SC injection comes in 162 mg/0.9

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FDA Approval Marketing Antibody Immune Response 102

BioPharma Reporter

MAY 25, 2021

An experimental recombinant protein nanoparticle vaccine that stimulates a strong immune response is hoping to address that inefficiency. Seasonal flu vaccines typically work 40-60% of the time, according to the US Centers for Disease Control and Prevention (CDC).

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Vaccination Vaccine Immune Response Production 91

World of DTC Marketing

DECEMBER 29, 2020

First, a novel approach was used that didn’t require traditional vaccine production in cell cultures or eggs. Once introduced into the human body, the protein-making machinery uses this genetic material in our cells to churn out the coronavirus “spike protein,” triggering an immune response.

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Vaccination Vaccine Development Clinical Trials 307

Scienmag

JUNE 2, 2021

When pigs get hit with significant illnesses during key stages of pregnancy, their immune response may negatively affect developing piglets, making them less productive on the farm. Credit: University of Illinois URBANA, Ill.

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Immune Response Production Development Research 98

Pharmaceutical Technology

AUGUST 15, 2022

The UK Medicines and Healthcare products Regulatory Agency (MHRA) has granted conditional authorisation for Moderna ’s Covid-19 booster vaccine, mRNA-1273.214 (Spikevax Bivalent Original/Omicron), for use in adults aged 18 years and above. 1 variant as well as the original 2020 strain.”.

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Vaccination Vaccine Immune Response Clinical Trials 214

Pharmaceutical Technology

MARCH 20, 2023

The collaboration, under a sponsored research agreement, will focus on mRNA vaccines that can help in modulating the normal immune response of the body for the treatment of certain autoimmune diseases as well as allergic conditions.

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Vaccination Vaccine Development Allergies 245

Medical Xpress

MAY 10, 2023

SLFN 12 shuts down viral protein production and helps virus-infected cells to escape from anti-HIV therapy and immune responses. These findings pave the way for improving therapeutic strategies that aim to cure HIV infections.

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Immune Response Protein Production Research 104

The Pharma Data

AUGUST 16, 2021

Better activation of innate and adaptive immune responses was achieved with CV2CoV, resulting in faster response onset, higher titers of antibodies, and stronger memory B and T cell activation as compared to the first-generation candidate, CVnCoV. “In Induction of innate immunity was investigated via specific cytokine markers.

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Immune Response Vaccination Vaccine Antibody 52

Camargo

DECEMBER 13, 2021

The development of biological products (or biologics) represents a major advancement in modern medicine, enabling the treatment of patients with many illnesses where no other therapeutics were previously available. The regulations regarding BLAs for therapeutic biological products are included in 21 CFR parts 600 , 601 , and 610.

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Development Production Immune Response Licensing 161

Pharmaceutical Technology

JUNE 30, 2022

This technology can stimulate an immune response with a dose up to 20 times lower than current vaccines, which enhances safety, lowers costs, and increases production speed. . At present, the vaccine is being analysed in clinical trials in the US, Brazil and South Korea.

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Vaccination Vaccine Clinical Trials Clinical Trials 162

Medical Xpress

JANUARY 17, 2025

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts.

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Immune Response Production 85

Medical Xpress

FEBRUARY 15, 2023

Researchers from Japan have found that white blood cells, known as B lymphocytes, have a pivotal role in promoting an emergent response to stimulate the in-demand production of innate immune cells during an infection.

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Immune Response Production Research 66

XTalks

OCTOBER 24, 2024

AX-158 offers a new class of therapy, by targeting immune responses without causing immunosuppression, making it a potentially safer option for long-term treatment, with results expected by the end of 2024.

Research 105

Research Dermatology Clinical Trials Clinical Trials 105

Scienmag

MAY 26, 2021

In series of samples collected from individuals vaccinated against COVID-19, an ultrasensitive test detected low concentrations of circulating antigen; Following robust production of antibodies, viral protein declined to undetectable levels The carefully orchestrated dance between the immune system and the viral proteins that induce immunity against (..)

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Immune Response Protein Vaccination Vaccine 54

XTalks

DECEMBER 30, 2024

SLE is an autoimmune disease where the immune system attacks healthy tissues, causing inflammation, pain and potential organ damage. Cenerimod modulates the immune response, reducing inflammation and preventing the production of harmful autoantibodies.

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Immune Response Gene Expression Drugs Trials 52

Pharmaceutical Technology

JULY 18, 2022

In clinical trials, the adjuvanted formulation induced the necessary immune response using a reduced amount of antigen versus a formulation without adjuvant, indicating that more doses could be available during a pandemic. H1N1, also called Swine Flu is the latest influenza pandemic in the country.

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Vaccination Vaccine Immune Response Clinical Trials 162

The Pharma Data

JULY 29, 2021

Loxo Oncology at Lilly, a research and development group of Eli Lilly and Company (NYSE: LLY), and Kumquat Biosciences today announced an exclusive collaboration focused on the discovery, development and commercialization of potential novel small molecules that stimulate tumor-specific immune responses.

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Immune Response Development Medicine Drugs 52

Pharmaceutical Technology

MAY 17, 2023

It has been designed for controlling the complement factor C5a, which is a protein that plays an important and harmful role in the immune response of the body. Together, we will now ramp up production under high pressure to roll out supply in order to serve the patient population in need as soon as possible.

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Manufacturing Immune Response Protein Antibody 130

Pharmaceutical Technology

MAY 10, 2023

Gilead Sciences research executive vice-president Flavius Martin stated: “The team at XinThera has developed research assets with the potential to target the DNA damage repair pathway in treating cancer and direct the body’s immune response in inflammatory diseases, both of which may improve outcomes for people living with these diseases.

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Immune Response DNA Clinical Trials Clinical Trials 130

Scienmag

MARCH 25, 2021

Cell Stem Cell, 2021, HOUSTON, TX – March 25, 2021 – Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections. Credit: Hormaechea-Agulla et al.,

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Immune Response Production Allergies Medicine 52

Pharmaceutical Technology

MAY 29, 2023

Novavax has received positive opinion from the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) for full marketing authorisation (MA) of its Covid vaccine, Nuvaxovid (NVX-CoV2373) , in the European Union (EU). The safety and efficacy of Nuvaxovid was evaluated as a primary series.

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Vaccination Vaccine Protein Immune Response 130

Pharmaceutical Technology

JANUARY 19, 2023

The findings showed that the Nuvaxovid booster dose increased immune responses compared to higher levels associated with the protection in Phase III clinical trials. Nuvaxovid demonstrated a significant antibody response when given as a booster dose after primary vaccination with other authorised Covid-19 doses in the COV-BOOST trial.

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Vaccination Vaccine Immune Response Protein 147

Pharmaceutical Technology

DECEMBER 6, 2022

Evaxion CEO Per Norlén said: “We believe that ExpreS 2 ion´s superb platforms for the production of complex proteins are a great match with our AI platform for target discovery and our novel technologies for inducing strong immune responses.

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Vaccination Vaccine Development Immune Response 130

Worldwide Clinical Trials

JUNE 21, 2024

Its primary challenges include: Production Delays : The time-intensive process of expanding TILs to therapeutic quantities poses logistical hurdles. Response Rates : To date, approximately 30% of patients are achieving objective responses, indicating considerable room for improvement.

Antibody 162

Antibody Clinical Trials Clinical Trials In-Vitro 162

pharmaphorum

JULY 18, 2022

“It is programmed and coded for the production of the full-length spike protein of the coronavirus. It then elicits an immune response against that spike protein. You have a response with immunoglobulins type G (antibodies) and robust cellular response with both CD4 and CD8 T-cells being activated,” Morgon states.

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Vaccination Vaccine Development Immune Response 138

Pharmaceutical Technology

FEBRUARY 26, 2023

It constitutes tumor infiltrating lymphocytes (TILs) isolated from the patient’s tumor further expanded and then infused back to the patient enabling patient robust immune response. It develops products based on its tumor-infiltrating lymphocyte (TIL) technology.

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Immune Response Production Drugs Clinical Trials 100

Pharmaceutical Technology

AUGUST 26, 2022

A 2015 study showed that both routes of administration (ROA) produce similar immune responses but that intradermal ROA produced more swelling at the injection site.) The EUA also allows subcutaneous administration to individuals under 18 years old who are at high risk of monkeypox. See Table 1).

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Vaccination Vaccine Immune Response Manufacturing 130

pharmaphorum

OCTOBER 5, 2022

Called NGoXIM, the vaccine is based on gonococcal OMVs combined with sustained-release microspheres containing recombinant human IL-12, supplied Intravacc’s US partner Therapyx, which are designed to boost the immune response to the antigens.

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Vaccination Vaccine Immune Response Bacterium 98

pharmaphorum

JUNE 21, 2021

BNT111 is the lead product candidate from BioNTech’s FixVac platform, and is based on a combination of four mRNA-encoded, tumour-associated antigens – NY-ESO-1, MAGE-A3, tyrosinase, and TPTE – that are designed to stimulate an immune response against a cancer.

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Vaccination Vaccine Immune Response Trials 145

XTalks

NOVEMBER 6, 2020

Symvivo’s bacTRL Gene Therapy Platform is designed and optimized to address limitations associated with typical vaccines, including the inability to accommodate large or multiple genes, lack of specificity to targeted tissue and poor control over immune response, says the company.

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Clinical Trials Clinical Trials Vaccination Vaccine 75

The Pharma Data

APRIL 15, 2022

We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives.

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Immune Response Vaccination Vaccine Clinical Trials 52

XTalks

APRIL 18, 2022

Related: BioNTech Unveils the BioNTainer, a Modular mRNA Vaccine Factory to Help Production in Africa. Accomplishing strong immune responses with low doses is crucial in the development of well-tolerated and highly effective vaccines. This can be achieved with the right technology that enables targeted vaccine delivery,” said U?

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Vaccination Vaccine Development Immune Response 105

pharmaphorum

SEPTEMBER 4, 2020

Personalized and precision medicines are naturally patient-centered (compared to traditional pharmaceuticals), as the individual patient is central to the product design. This means not only adopting collaborative thinking during the design phase but also during production and development. visible to the patient) and back-end (i.e.

Medicine 59

Medicine Production Genetic Engineering Genetics 59

XTalks

OCTOBER 12, 2021

The vaccine was tested in rats and showed strong, immediate and long-lasting immune responses to confer protection against the disease. is an autoantigen, which means it is an endogenous antigen that triggers an immune response in the body. KO animals. It increased anti-14-3-3?

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Vaccination Vaccine Research Immune Response 105

XTalks

DECEMBER 14, 2021

Moderna revealed the first interim results from a small, Phase I study of its mRNA-based influenza vaccine, which showed that the vaccine had no significant safety concerns and elicited immune responses against four strains of the influenza virus. There were no significant safety findings reported through day 29. Mixed Results.

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Vaccination Vaccine Immune Response Antibody 98