This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
Fortunately, advances in clinical research are providing hope for better treatments and outcomes. With the support of global networks like ours at Worldwide Clinical Trials (Worldwide), autoimmune and bone health research is accelerating, providing new solutions to patients around the world.
Fortunately, advances in clinical research are providing hope for better treatments and outcomes. With the support of global networks like ours at Worldwide Clinical Trials (Worldwide), autoimmune and bone health research is accelerating, providing new solutions to patients around the world.
Scientists at the National Institutes of Health (NIH) unit National Institute of Neurological Disorders and Stroke (NINDS) have found that Covid-19-induced immuneresponse could damage the blood vessels of the brain and may lead to short and long-term neurological symptoms. .
In a world first, scientists at Duke-NUS Medical School and colleagues in Singapore have sequenced the response to viral infection in colony-bred cave nectar bats (Eonycteris spelaea) at single-cell resolution.
The Pfizer/BioNTech vaccine appears to work against an important mutation in the new coronavirus variants causing havoc in the UK and South Africa, according to research from the drugs giant. Researchers plan to run similar tests to check if the vaccine works against this and other mutations found in the UK and South African variants.
But scientists in the emerging field of immunometabolism are finding obesity also interferes with the body’s immuneresponse, putting obese people at greater risk of infection from pathogens such as influenza and the novel coronavirus. And it’s getting worse.
Researchers at Mass Eye and Ear and Northeastern University have discovered a previously unidentified immuneresponse inside the nose that fights off viruses responsible for upper respiratory infections.
Army scientists determined that the body’s own natural immuneresponse contributes to disease severity in mice infected with Crimean-Congo hemorrhagic fever virus (CCHFV), which causes a widespread tick-borne viral infection in humans.
Researchers at the University of Southampton have gained unprecedented new insight into the key properties of an antibody needed to fight off cancer. The interdisciplinary study, published in Science Immunology, revealed how changing the flexibility of the antibody could stimulate a stronger immuneresponse.
The findings provide direction for future vaccines or therapies that may offer broader protection against variants LA JOLLA, CA–Fast-spreading variants of the COVID-19-causing coronavirus, SARS-CoV-2, carry mutations that enable the virus to escape some of the immuneresponse created naturally or by vaccination.
The first peer-reviewed study in North America examining the timing between the first and second doses of COVID-19 mRNA vaccines shows that a longer dose interval leads to a stronger immuneresponse. The study is funded by the Government of Canada through its COVID-19 Immunity Task Force (CITF).
Maryland, US-based company Altimmune is among the biotechs and research labs trying to find more convenient alternatives and believes a nasal vaccine spray that is stable at room temperature could be the answer. A nasal delivery method will also produce an immuneresponse at the point where the virus enters the body.
Northwestern Medicine scientists have identified a new therapeutic target for tumors and developed a compound which slowed tumor growth and bolsters immuneresponses in mice, according to research published in Science Advances.
Further scientific research into the virus and recognition that it was not like influenza A, a flu virus known to cause bronchitis, would transpire over the next 30 years. . If your body develops an immuneresponse—the goal of vaccination—there is a possibility you may test positive on some antibody tests.
The drug diABZI — which activates the body’s innate immuneresponse — was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2, according to scientists in the Perelman School of Medicine at the University of Pennsylvania.
Moderna’s vaccines deliver HIV-specific antigens discovered by researchers at IAVI and Scripps Research that have already been tested in a proof-of-concept study carried out last year using an adjuvant protein vaccine approach. HVAD #HVAD2022 pic.twitter.com/KLrVRXtEAv. — Moderna (@moderna_tx) May 18, 2022.
In 2021, a group of scientists led by researchers at the University of North Carolina at Chapel Hill, Weill Cornell Medicine and NewYork-Presbyterian reported that the Moderna mRNA vaccine and a protein-based vaccine candidate containing an adjuvant, a substance that enhances immuneresponses, elicited durable neutralizing antibody responses to SARS-CoV-2 (..)
COLUMBUS, Ohio – Driving up the immuneresponse at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.
Scientists in the US say they have developed an mRNA-based vaccine that encompasses all 20 known subtypes of influenza that could form the basis of a future universal jab. The post mRNA can deliver universal flu vaccine, say US researchers appeared first on.
A new effort is under way to understand how the immune system responds to coronavirus. Scientists from 17 UK research centres are attempting to answer questions such as how long immunity lasts and why disease severity varies so much. Does getting coronavirus make you immune? It has received £6.5m
During this ground-breaking study, scientists from the Spanish National Research Council and the University of Surrey investigated the immuneresponse of […].
The Com-COV trial compared two shots with Pfizer/BioNTech’s Comirnaty, two doses of AstraZeneca’s Vaxzevria, and a mixed regimen of one of each jab, and found that all were effective at stimulating a “robust” immuneresponse against the coronavirus, according to the investigators.
7, 2020 — Scientists say they may be getting closer to creating a universal flu vaccine. In an early-stage clinical trial with 65 volunteers in the United States, an experimental vaccine triggered strong immuneresponses to a wide range of flu virus strains and subtypes. MONDAY, Dec.
For their remarkable scientific contributions, doctoral student Julia Klaus, Zurich University VetSuisse Faculty, and Dr Yasmin Parr from the MRC-University of Glasgow, Centre for Virus Research, have received the 2021 ABCD Young Scientist Award. To foster young talent development in the feline health research community.
The far more boring truth is that scientists are not magicians or prophets and estimations cannot always be precise. For Covid-19 the herd immunity threshold is 70% but this is only a rough estimate based on the current numbers we’re seeing. . Thus, herd immunity wouldn’t work in this scenario.
More than three decades ago, scientists at the National Cancer Institute began exploring ways to fight cancer using the patient’s immune system. Quantifiable results: Researchers can obtain relative percentages and learn the absolute count and number of receptors in a cell. Flow cytometry in biomarker research.
At the same time, the UK’s National Institute for Health and Care excellence (NICE) is developing guidance to help doctors manage the cases of vaccine-induced immune thrombocytopenia and thrombosis (VITT) and low blood platelet counts that have been seen with the COVID-19 vaccines.
Researchers at KU Leuven in Belgium have found a potential mechanism underlying irritable bowel syndrome (IBS) that involves activation of immune cells primed by past gastrointestinal infections. The research findings were published in the journal Nature. Related: Monitoring Patients with IBS or Kidney Failure?
Interim results from a phase 1/2 clinical trial show the immuneresponse from Sanofi/GSK’s vaccine produced a lower immuneresponse in older adults. While antibody levels were comparable to those seen in recovering COVID-19 patients in adults aged 18-49, the response was lower in older adults.
Eric Gilbert explores how data science techniques like text mining are speeding up research into areas such as pancreatic cancer. As a result, many researchers and organisations are relying more on digital technologies and data science techniques to help break down and digest the information available.
officials ramped up efforts to vaccinate more Americans, scientists around the world wrestled with whether it would make sense to delay the second doses everyone will need so more people can be vaccinated more quickly. “There is a path forward if you can show that two lower doses yield a similar immuneresponse,” Dean said.
Predicting protein structures would typically be a time-consuming process, but now scientists can use technology to better analyse viruses, thus helping in the search for a vaccine that can trigger an immuneresponse. Scientists are using AI to sift through existing literature on a disease and study its disease’s structure.
BioNTech gets the opportunity to tap into the NHS as a source of subjects for its cancer vaccine studies, as well as access to genomics and health data resources, and in return will open an R&D centre in Cambridge, employing more than 70 scientists, as well as an office in London.
New research into Alzheimer’s disease (AD) suggests that secondary infections and new inflammatory events amplify the brain’s immuneresponse and affect memory in mice and in humans – even when these secondary events occur outside the brain.
Increasing research into the gut microbiome has revealed new and emerging roles for the ‘good bacteria’ in our bodies, with the latest being a new study that shows how they can help the immune system attack cancer cells.
Established by the Multiple Sclerosis International Federation (MSIF) in 2009, World MS Day has quickly grown to be an influential movement that brings together various stakeholders that include patients and caregivers, researchers and healthcare professionals across more than 90 countries.
million results and participants – making it one of the largest real-life vaccine effectiveness studies on record, according to the researchers. The study was carried out from provided by people who logged COVID-19 vaccinations and test results via an app, and involved more than 1.2 J&J reports booster dose data.
scientists and public health experts, it was announced that there was a growing new strain of the SARS-CoV-2 virus that causes COVID-19. Not all scientists believe it is more contagious, although most are wondering how B.1.1.7 Researchers say, however, they have never seen a virus acquire more than a dozen mutations at once.
That’s because the mutations that led to the variant’s emergence aren’t found in the regions of the virus that stimulates one type of cellular immuneresponse, says an international research team from Johns Hopkins Medicine, in collaboration with the National Institute of Allergy and Infectious Diseases (NIAID) and ImmunoScape, a U.S.-Singapore
Researchers from the University of Texas Medical Branch based their findings on lab tests using SARS-CoV-2 coronaviruses that were genetically engineered to have the same mutations as those in the strain that is causing scientists so much concern.
Most experts believed that it would take a few years for the virus to become seasonal in nature after the global population gains greater immunity and as people return to their pre-pandemic lives, the article detailed. In addition, immunity against the infection is found to wane for both previously infected individuals and the vaccinated.
Moderna’s COVID-19 vaccine triggers an immuneresponse in older adults. At Northwestern University, the researchers combined chemotherapy with an investigational bromodomain (BET) inhibitor to target breast cancer that had spread to the brain in mouse models. White fat, in contrast, can build up and cause obesity.
In the second of a three-part series, Ben Hargreaves looks at the importance of early-stage research into various emerging infectious disease threats and how it saved precious time in the work to develop a working vaccine during the current pandemic. The institute also led and funded early-stage clinical research into the vaccine candidate.
They are often used to mimic or enhance natural biological processes, such as immuneresponses. Immunogenicity : Small Molecules: Generally have a lower risk of inducing an immuneresponse in the body. In both cases, clinical research must be meticulously designed to address these complexities.
We organize all of the trending information in your field so you don't have to. Join 21,000+ users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content