Immune Response and Scientist - Clinical Research Informer

Covid-19 induced immune response may damage brain, NINDS study finds

Pharmaceutical Technology

JULY 6, 2022

Scientists at the National Institutes of Health (NIH) unit National Institute of Neurological Disorders and Stroke (NINDS) have found that Covid-19-induced immune response could damage the blood vessels of the brain and may lead to short and long-term neurological symptoms. .

Immune Response

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Scientists blueprint bacterial enzyme believed to “stealthily” suppress immune response

Scienmag

JULY 12, 2021

Scientists have produced the first fine-detail molecular blueprints of a bacterial enzyme known as Lit, which is suspected to play a “stealthy” role in the progression of infection by reducing the immune response.

Immune Response

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Scientists reveal first close-up look at bats' immune response to live infection

Medical Xpress

NOVEMBER 23, 2022

In a world first, scientists at Duke-NUS Medical School and colleagues in Singapore have sequenced the response to viral infection in colony-bred cave nectar bats (Eonycteris spelaea) at single-cell resolution.

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Huddersfield scientists first to show how coronavirus triggers immune response in brain

Scienmag

MARCH 17, 2022

The study, published in the journal Molecular Neurobiology led by the University’s Dr Mayo Olajide, describes how the spike protein used by the coronavirus to enter human cells can have a similar effect on the brain’s immune cells as it does with the rest of the body Credit: University of Huddersfield The study, published in […].

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Scientists reveal structural details of how SARS-CoV-2 variants escape immune response

Scienmag

MAY 20, 2021

The findings provide direction for future vaccines or therapies that may offer broader protection against variants LA JOLLA, CA–Fast-spreading variants of the COVID-19-causing coronavirus, SARS-CoV-2, carry mutations that enable the virus to escape some of the immune response created naturally or by vaccination.

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Johns Hopkins Scientists Discover Possible Key to Controlling COVID-19 Immune Response

BioSpace

OCTOBER 18, 2020

They believe that by inhibiting factor D, it would reduce the inflammatory reactions that make COVID-19 so deadly.

Immune Response

Immune Response Scientist

Wistar scientists identify novel therapeutic approach to re-activate immune response against tumors

Scienmag

JUNE 21, 2022

Therefore, new therapeutic options such as targeted therapy that boosts antitumor immunity are needed to improve ovarian cancer treatment efficacy and patient survival. PHILADELPHIA — (June 21, 2022) — Due to the development of resistance to chemotherapy and recurring tumors, patients with ovarian cancer often have low survival rates.

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SARS-CoV-2 curtails immune response in the gut

Scienmag

APRIL 27, 2021

Scientists transform human intestinal cells into ‘mini guts’ to follow infection process Credit: Mohammed Shahraz, Sergio Triana/EMBL; Camila Metz-Zumaran/Heidelberg University In an effort to determine the potential for COVID-19 to begin in a person’s gut, and to better understand how human cells respond to SARS-CoV-2, the scientists (..)

Immune Response

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Second-Generation mRNA COVID-19 Vaccine Candidate, CV2CoV, Demonstrates Improved Immune Response and Protection in Preclinical Study

The Pharma Data

AUGUST 16, 2021

Better activation of innate and adaptive immune responses was achieved with CV2CoV, resulting in faster response onset, higher titers of antibodies, and stronger memory B and T cell activation as compared to the first-generation candidate, CVnCoV. “In Induction of innate immunity was investigated via specific cytokine markers.

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Regulating immunological memory may help immune system fight disease, study finds

Medical Xpress

JANUARY 20, 2023

Scientists have long sought to better understand the human body's immune responses that occur during various diseases, including cancer and inflammatory diseases.

Immune Response

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Scientists uncover biological explanation for why upper respiratory infections are more common in colder temperatures

Medical Xpress

DECEMBER 6, 2022

Researchers at Mass Eye and Ear and Northeastern University have discovered a previously unidentified immune response inside the nose that fights off viruses responsible for upper respiratory infections.

Immune Response

Immune Response Scientist Research

Scientists identify protein crucial to tumor cells' metabolism and immune evasion

Medical Xpress

FEBRUARY 14, 2023

This limits glucose availability for immune cells and therefore dampens the body's anti-cancer immune response. Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread.

Immune Response

Immune Response Protein Scientist

Scientists analyze structure of antibodies that could be key to more effective cancer treatments

Scienmag

JULY 8, 2022

The interdisciplinary study, published in Science Immunology, revealed how changing the flexibility of the antibody could stimulate a stronger immune response. Researchers at the University of Southampton have gained unprecedented new insight into the key properties of an antibody needed to fight off cancer.

Antibody

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Pfizer/BioNTech vaccine may work against new virus mutation, scientists say

pharmaphorum

JANUARY 8, 2021

Pfizer joined with scientists from the University of Texas Medical Branch to conduct the study, which indicated the vaccine was effective at neutralising virus with the mutation known as N501Y. The post Pfizer/BioNTech vaccine may work against new virus mutation, scientists say appeared first on.

Scientist

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Discovery of 'Goldilocks' effect of nanoparticles offers significant hope for improved vaccines

Medical Xpress

JANUARY 20, 2023

Scientists have discovered there is a "Goldilocks" effect in identifying the size of a "vaccine adjuvant" that can trigger strong immune responses and, as an example, have shown that a safe, biodegradable adjuvant can boost the action of cancer-killing cells—if the particles are the correct size.

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Scientists target coronavirus immunity puzzle

The Pharma Data

AUGUST 27, 2020

A new effort is under way to understand how the immune system responds to coronavirus. Scientists from 17 UK research centres are attempting to answer questions such as how long immunity lasts and why disease severity varies so much. Does getting coronavirus make you immune? Image copyright. SCIENCE PHOTO LIBRARY.

Scientist

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Immune surprise: Recently evolved alarm molecule drives inflammation

Medical Xpress

DECEMBER 16, 2022

Scientists from Trinity College Dublin have made an important breakthrough in understanding how inflammation is regulated. They have just discovered that a key immune alarm protein previously believed to calm down the immune response actually does the opposite.

Immune Response

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Sanford Burnham Prebys receives $3M NIH award for drugs that restore immune response to COVID-19

Scienmag

SEPTEMBER 15, 2020

Scientists will study how SARS-CoV-19 hijacks the immune system and creates a ‘cytokine storm’ Credit: Sanford Burnham Prebys Medical Discovery Institute.

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Study identifies new therapeutic target for tumor treatment

Medical Xpress

DECEMBER 19, 2022

Northwestern Medicine scientists have identified a new therapeutic target for tumors and developed a compound which slowed tumor growth and bolsters immune responses in mice, according to research published in Science Advances.

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New studies offer theory on cause of unusual hepatitis cases in kids

STAT News

JULY 25, 2022

Two new and as-yet-unpublished studies from scientists in the United Kingdom theorize that children who have developed the hepatitis cases may have been co-infected with two different viruses and had a genetic predisposition to have an over-exuberant immune response when that happened. Read the rest…

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Are Scientists Close to a ‘Universal’ Flu Vaccine?

The Pharma Data

DECEMBER 7, 2020

7, 2020 — Scientists say they may be getting closer to creating a universal flu vaccine. In an early-stage clinical trial with 65 volunteers in the United States, an experimental vaccine triggered strong immune responses to a wide range of flu virus strains and subtypes. MONDAY, Dec.

Scientist

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2021 Young Scientist Award winners announced

The Pharma Data

JUNE 30, 2021

For their remarkable scientific contributions, doctoral student Julia Klaus, Zurich University VetSuisse Faculty, and Dr Yasmin Parr from the MRC-University of Glasgow, Centre for Virus Research, have received the 2021 ABCD Young Scientist Award. To foster young talent development in the feline health research community.

Scientist

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Research sheds light on crimean-congo hemorrhagic fever disease process

Scienmag

MAY 20, 2022

Army scientists determined that the body’s own natural immune response contributes to disease severity in mice infected with Crimean-Congo hemorrhagic fever virus (CCHFV), which causes a widespread tick-borne viral infection in humans.

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Immune Response Research Scientist

Boosting anti-cancer action by driving up immunity at tumor site

Scienmag

DECEMBER 14, 2021

COLUMBUS, Ohio – Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.

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Immune Response Scientist Research

Experimental COVID-19 vaccine offers long-term protection against severe disease

Medical Xpress

DECEMBER 1, 2022

In 2021, a group of scientists led by researchers at the University of North Carolina at Chapel Hill, Weill Cornell Medicine and NewYork-Presbyterian reported that the Moderna mRNA vaccine and a protein-based vaccine candidate containing an adjuvant, a substance that enhances immune responses, elicited durable neutralizing antibody responses to SARS-CoV-2 (..)

Vaccination

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New method to assist fast-tracking of vaccines for pre-clinical tests

Scienmag

JANUARY 18, 2021

Novel tuberculosis vaccine demonstrated strong immune response in mice Credit: University of Sydney Scientists in Australia have developed a method for the rapid synthesis of safe vaccines, an approach that can be used to test vaccine strategies against novel pandemic pathogens such as SARS-CoV-2, the virus that causes COVID-19.

Vaccination

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STAT+: Pharmalittle: Merck KGaA probed by French court for misleading info; former Genentech scientists given prison terms over trade-secret theft

STAT News

OCTOBER 19, 2022

1 subvariant of Omicron generated a strong immune response against that variant, with antibody levels staying high for at least three months , Reuters notes. Omicron-tailored Have a wonderful day, and please do stay in touch. … Moderna disclosed that its Covid-19 vaccine booster targeting the BA.1

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Potential treatment of autoimmune diseases revealed in new study

Medical Xpress

MARCH 6, 2023

Scientists in Japan have revealed a chemical compound that could be used for the treatment of various autoimmune diseases like multiple sclerosis and rheumatoid arthritis. These diseases occur when the body's immune response goes awry.

Immune Response

Immune Response Scientist

Can controlling retinoic acid be a key to preventing infections in the gut?

Medical Xpress

MARCH 28, 2023

A team of scientists from the Renaissance School of Medicine (RSOM) at Stony Brook University has identified a distinct role of retinoic acid, a metabolite of vitamin A, during the immune response of the gut.

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Coya Therapeutics expands COYA 301 patent estate

Pharmaceutical Technology

JUNE 21, 2023

Findings from the preclinical model, published by scientists from the University of Nebraska Medical Center, showed that ld IL-2 treatment induced overexpression of immunosuppressive Treg cell markers in the treatment-specific Treg population. This had a potent neuroprotective effect on nigral dopaminergic neurons in affected mice.

In-Vivo

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Gel fights drug-resistant bacteria and induces body’s natural immune defense

Scienmag

OCTOBER 14, 2021

In the fight against multidrug-resistant bacteria, scientists in Sweden have developed a new kind of antibiotic-free protection for wounds that kills drug-resistant bacteria and induces the body’s own immune responses to fight infections.

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B cell activating factor possible key to hemophilia immune tolerance

Scienmag

APRIL 19, 2021

A group of scientists have just made a key discovery that could prevent and eradicate immune responses that lead to treatment failure in about one-third of people with severe hemophilia A. Hemophilia is the most common severe inherited bleeding disorder in men.

Immune Response

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Deeper insight into how tick spit suppresses cattle immunity

Scienmag

JANUARY 28, 2021

Credit: itabajara da Silva Vaz Jr) A tick saliva study reveals immune responses that could lead to better protection for cattle.

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The Lancet: New polio vaccine against strain that threatens eradication is safe and generates immune response in adults, young children, and infants

Scienmag

DECEMBER 9, 2020

Scientists have developed the first poliovirus […].

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Penn researchers discover drug that blocks multiple SARS-CoV-2 variants in mice

Scienmag

MAY 28, 2021

The drug diABZI — which activates the body’s innate immune response — was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2, according to scientists in the Perelman School of Medicine at the University of Pennsylvania.

Immune Response

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Finding clues to a successful immune response in the T cells of COVID-19 patients

Scienmag

AUGUST 21, 2020

While antibodies may fade fast, T cells appear to be long-lived and might confer lasting immunity.

Immune Response

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Removal of a gene could render lethal poxviruses harmless

Scienmag

SEPTEMBER 18, 2020

During this ground-breaking study, scientists from the Spanish National Research Council and the University of Surrey investigated the immune response of […].

Gene

Gene Immune Response Scientist Research

Innovation in Autoimmune and Bone Health Research: Driving Progress for Better Patient Outcomes

Worldwide Clinical Trials

OCTOBER 14, 2024

Scientists now use cutting-edge techniques, including biological therapies that target specific immune system components and precision medicine approaches that personalize treatment plans based on a patient’s genetic profile.

Research

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Americans continue to neglect their health

World of DTC Marketing

AUGUST 21, 2020

But scientists in the emerging field of immunometabolism are finding obesity also interferes with the body’s immune response, putting obese people at greater risk of infection from pathogens such as influenza and the novel coronavirus.

Immune Response

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Altimmune begins trial of nasal vaccine for COVID-19

pharmaphorum

FEBRUARY 25, 2021

A nasal delivery method will also produce an immune response at the point where the virus enters the body. The company announced a phase 1 trial is beginning of its nasal spray vaccine just as scientists in the UK said they are considering a similar approach.

Vaccination

Vaccination Vaccine Immune Response Trials

Innovating in Autoimmune and Bone Health Research: Driving Progress for Better Patient Outcomes

Worldwide Clinical Trials

OCTOBER 14, 2024

Scientists now use cutting-edge techniques, including biological therapies that target specific immune system components and precision medicine approaches that personalize treatment plans based on a patient’s genetic profile.

Research

Research Clinical Trials Clinical Trials Immune Response

As U.S. COVID Vaccine Campaign Struggles, Scientists Weigh Ways to Speed Uptake

The Pharma Data

JANUARY 4, 2021

officials ramped up efforts to vaccinate more Americans, scientists around the world wrestled with whether it would make sense to delay the second doses everyone will need so more people can be vaccinated more quickly. “There is a path forward if you can show that two lower doses yield a similar immune response,” Dean said.

Scientist

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Nasal vaccine against COVID-19 prevents infection in mice

Scienmag

AUGUST 21, 2020

Nasal delivery produces more widespread immune response than intramuscular injection Credit: Hassan et al. Scientists at Washington University School of Medicine in St.

Vaccination

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Vaccine ingredients could be hiding in small molecule libraries

Scienmag

OCTOBER 1, 2020

Identifying potential adjuvants just […].

Vaccination

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Covid-19 induced immune response may damage brain, NINDS study finds

Scientists blueprint bacterial enzyme believed to “stealthily” suppress immune response

Webinars

Trending Sources

Scientists reveal first close-up look at bats' immune response to live infection

Webinars

Huddersfield scientists first to show how coronavirus triggers immune response in brain

Scientists reveal structural details of how SARS-CoV-2 variants escape immune response

Johns Hopkins Scientists Discover Possible Key to Controlling COVID-19 Immune Response

Wistar scientists identify novel therapeutic approach to re-activate immune response against tumors

SARS-CoV-2 curtails immune response in the gut

Second-Generation mRNA COVID-19 Vaccine Candidate, CV2CoV, Demonstrates Improved Immune Response and Protection in Preclinical Study

Regulating immunological memory may help immune system fight disease, study finds

Scientists uncover biological explanation for why upper respiratory infections are more common in colder temperatures

Scientists identify protein crucial to tumor cells' metabolism and immune evasion

Scientists analyze structure of antibodies that could be key to more effective cancer treatments

Pfizer/BioNTech vaccine may work against new virus mutation, scientists say

Discovery of 'Goldilocks' effect of nanoparticles offers significant hope for improved vaccines

Scientists target coronavirus immunity puzzle

Immune surprise: Recently evolved alarm molecule drives inflammation

Sanford Burnham Prebys receives $3M NIH award for drugs that restore immune response to COVID-19

Study identifies new therapeutic target for tumor treatment

New studies offer theory on cause of unusual hepatitis cases in kids

Are Scientists Close to a ‘Universal’ Flu Vaccine?

2021 Young Scientist Award winners announced

Research sheds light on crimean-congo hemorrhagic fever disease process

Boosting anti-cancer action by driving up immunity at tumor site

Experimental COVID-19 vaccine offers long-term protection against severe disease

New method to assist fast-tracking of vaccines for pre-clinical tests

STAT+: Pharmalittle: Merck KGaA probed by French court for misleading info; former Genentech scientists given prison terms over trade-secret theft

Potential treatment of autoimmune diseases revealed in new study

Can controlling retinoic acid be a key to preventing infections in the gut?

Coya Therapeutics expands COYA 301 patent estate

Gel fights drug-resistant bacteria and induces body’s natural immune defense

B cell activating factor possible key to hemophilia immune tolerance

Deeper insight into how tick spit suppresses cattle immunity

The Lancet: New polio vaccine against strain that threatens eradication is safe and generates immune response in adults, young children, and infants

Penn researchers discover drug that blocks multiple SARS-CoV-2 variants in mice

Finding clues to a successful immune response in the T cells of COVID-19 patients

Removal of a gene could render lethal poxviruses harmless

Innovation in Autoimmune and Bone Health Research: Driving Progress for Better Patient Outcomes

Americans continue to neglect their health

Altimmune begins trial of nasal vaccine for COVID-19

Innovating in Autoimmune and Bone Health Research: Driving Progress for Better Patient Outcomes

As U.S. COVID Vaccine Campaign Struggles, Scientists Weigh Ways to Speed Uptake

Nasal vaccine against COVID-19 prevents infection in mice

Vaccine ingredients could be hiding in small molecule libraries

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