Worldwide Clinical Trials

OCTOBER 14, 2024

Scientists now use cutting-edge techniques, including biological therapies that target specific immune system components and precision medicine approaches that personalize treatment plans based on a patient’s genetic profile.

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Research Clinical Trials Clinical Trials Immune Response 130

Scienmag

JUNE 21, 2022

Therefore, new therapeutic options such as targeted therapy that boosts antitumor immunity are needed to improve ovarian cancer treatment efficacy and patient survival. PHILADELPHIA — (June 21, 2022) — Due to the development of resistance to chemotherapy and recurring tumors, patients with ovarian cancer often have low survival rates.

Immune Response 81

Immune Response Scientist Development 81

World of DTC Marketing

AUGUST 21, 2020

But scientists in the emerging field of immunometabolism are finding obesity also interferes with the body’s immune response, putting obese people at greater risk of infection from pathogens such as influenza and the novel coronavirus.

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Immune Response Vaccine Vaccination Scientist 238

Medical Xpress

JANUARY 20, 2023

Scientists have long sought to better understand the human body's immune responses that occur during various diseases, including cancer and inflammatory diseases.

Immune Response 109

Immune Response Regulation Scientist 109

Scienmag

APRIL 27, 2021

Scientists transform human intestinal cells into ‘mini guts’ to follow infection process Credit: Mohammed Shahraz, Sergio Triana/EMBL; Camila Metz-Zumaran/Heidelberg University In an effort to determine the potential for COVID-19 to begin in a person’s gut, and to better understand how human cells respond to SARS-CoV-2, the scientists (..)

Immune Response 68

Immune Response Scientist Medicine 68

Medical Xpress

DECEMBER 6, 2022

Researchers at Mass Eye and Ear and Northeastern University have discovered a previously unidentified immune response inside the nose that fights off viruses responsible for upper respiratory infections.

Immune Response 98

Immune Response Scientist Research 98

Scienmag

MAY 20, 2021

The findings provide direction for future vaccines or therapies that may offer broader protection against variants LA JOLLA, CA–Fast-spreading variants of the COVID-19-causing coronavirus, SARS-CoV-2, carry mutations that enable the virus to escape some of the immune response created naturally or by vaccination.

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Immune Response Scientist Vaccination Vaccine 40

Scienmag

JULY 8, 2022

The interdisciplinary study, published in Science Immunology, revealed how changing the flexibility of the antibody could stimulate a stronger immune response. Researchers at the University of Southampton have gained unprecedented new insight into the key properties of an antibody needed to fight off cancer.

Antibody 86

Antibody Immune Response Scientist Research 86

Medical Xpress

JANUARY 20, 2023

Scientists have discovered there is a "Goldilocks" effect in identifying the size of a "vaccine adjuvant" that can trigger strong immune responses and, as an example, have shown that a safe, biodegradable adjuvant can boost the action of cancer-killing cells—if the particles are the correct size.

Immune Response 98

Immune Response Vaccine Vaccination Scientist 98

STAT News

JULY 25, 2022

Two new and as-yet-unpublished studies from scientists in the United Kingdom theorize that children who have developed the hepatitis cases may have been co-infected with two different viruses and had a genetic predisposition to have an over-exuberant immune response when that happened. Read the rest…

Immune Response 105

Immune Response Genetics Scientist Development 105

Medical Xpress

FEBRUARY 14, 2023

This limits glucose availability for immune cells and therefore dampens the body's anti-cancer immune response. Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread.

Immune Response 75

Immune Response Protein Scientist 75

Scienmag

OCTOBER 1, 2020

Identifying potential adjuvants just […].

Vaccine 93

Vaccine Vaccination Immune Response Scientist 93

Scienmag

JANUARY 18, 2021

Novel tuberculosis vaccine demonstrated strong immune response in mice Credit: University of Sydney Scientists in Australia have developed a method for the rapid synthesis of safe vaccines, an approach that can be used to test vaccine strategies against novel pandemic pathogens such as SARS-CoV-2, the virus that causes COVID-19.

Vaccine 93

Vaccine Vaccination Immune Response Scientist 93

The Pharma Data

DECEMBER 4, 2021

The first peer-reviewed study in North America examining the timing between the first and second doses of COVID-19 mRNA vaccines shows that a longer dose interval leads to a stronger immune response. The study is funded by the Government of Canada through its COVID-19 Immunity Task Force (CITF).

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Immune Response Vaccine Vaccination Antibody 52

Scienmag

DECEMBER 9, 2020

Scientists have developed the first poliovirus […].

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Immune Response Vaccine Vaccination Scientist 75

The Pharma Data

AUGUST 16, 2021

Better activation of innate and adaptive immune responses was achieved with CV2CoV, resulting in faster response onset, higher titers of antibodies, and stronger memory B and T cell activation as compared to the first-generation candidate, CVnCoV. “In Induction of innate immunity was investigated via specific cytokine markers.

Immune Response 52

Immune Response Vaccination Vaccine Antibody 52

Scienmag

SEPTEMBER 15, 2020

Scientists will study how SARS-CoV-19 hijacks the immune system and creates a ‘cytokine storm’ Credit: Sanford Burnham Prebys Medical Discovery Institute.

Immune Response 60

Immune Response Scientist Drugs Allergies 60

Medical Xpress

DECEMBER 16, 2022

Scientists from Trinity College Dublin have made an important breakthrough in understanding how inflammation is regulated. They have just discovered that a key immune alarm protein previously believed to calm down the immune response actually does the opposite.

Immune Response 80

Immune Response Protein Scientist Regulation 80

pharmaphorum

FEBRUARY 25, 2021

A nasal delivery method will also produce an immune response at the point where the virus enters the body. The company announced a phase 1 trial is beginning of its nasal spray vaccine just as scientists in the UK said they are considering a similar approach.

Vaccine 111

Vaccine Vaccination Immune Response Trials 111

Scienmag

MAY 20, 2022

Army scientists determined that the body’s own natural immune response contributes to disease severity in mice infected with Crimean-Congo hemorrhagic fever virus (CCHFV), which causes a widespread tick-borne viral infection in humans.

Immune Response 84

Immune Response Research Scientist 84

pharmaphorum

JANUARY 15, 2021

In order to make the best use of scarce vaccine resources the UK has opted to extend the time between doses to up to 12 weeks, a strategy that has been criticised by some scientists who are fearful that it could cause vaccine-tolerant strains of the virus to emerge.

Vaccine 119

Vaccine Vaccination Immune Response Antibody 119

Medical Xpress

DECEMBER 19, 2022

Northwestern Medicine scientists have identified a new therapeutic target for tumors and developed a compound which slowed tumor growth and bolsters immune responses in mice, according to research published in Science Advances.

Immune Response 75

Immune Response Scientist Medicine Development 75

STAT News

OCTOBER 19, 2022

1 subvariant of Omicron generated a strong immune response against that variant, with antibody levels staying high for at least three months , Reuters notes. Omicron-tailored Have a wonderful day, and please do stay in touch. … Moderna disclosed that its Covid-19 vaccine booster targeting the BA.1

Immune Response 98

Immune Response Scientist Vaccine Vaccination 98

World of DTC Marketing

APRIL 11, 2021

A second study by scientists in the United States, published alongside the Imperial-led one in the journal Nature, estimated that lockdowns in China, South Korea, Italy, Iran, France and the United States had prevented or delayed around 530 million COVID-19 cases.

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Vaccination Vaccine Clinical Trials Clinical Trials 303

Scienmag

DECEMBER 14, 2021

COLUMBUS, Ohio – Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.

Immune Response 67

Immune Response Scientist Research 67

The Pharma Data

AUGUST 27, 2020

A new effort is under way to understand how the immune system responds to coronavirus. Scientists from 17 UK research centres are attempting to answer questions such as how long immunity lasts and why disease severity varies so much. Does getting coronavirus make you immune? Image copyright. SCIENCE PHOTO LIBRARY.

Scientist 52

Scientist Immune Response Research Vaccine 52

Pharmaceutical Technology

JUNE 21, 2023

Findings from the preclinical model, published by scientists from the University of Nebraska Medical Center, showed that ld IL-2 treatment induced overexpression of immunosuppressive Treg cell markers in the treatment-specific Treg population. This had a potent neuroprotective effect on nigral dopaminergic neurons in affected mice.

In-Vivo 130

In-Vivo Immune Response Clinical Trials Clinical Trials 130

pharmaphorum

MAY 19, 2022

It codes for an antigen called eOD-GT8 60mer and, in the study, stimulated a targeted B-cell immune response in 97% of vaccine recipients. One candidate – mRNA-1644 – has already shown its potential in an earlier phase 1 trial (IAVI G001) run in the US. HVAD #HVAD2022 pic.twitter.com/KLrVRXtEAv.

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Vaccine Vaccination Trials Immune Response 145

pharmaphorum

JUNE 29, 2021

The Com-COV trial compared two shots with Pfizer/BioNTech’s Comirnaty, two doses of AstraZeneca’s Vaxzevria, and a mixed regimen of one of each jab, and found that all were effective at stimulating a “robust” immune response against the coronavirus, according to the investigators.

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Immune Response Vaccine Vaccination Antibody 128

Medical Xpress

DECEMBER 1, 2022

In 2021, a group of scientists led by researchers at the University of North Carolina at Chapel Hill, Weill Cornell Medicine and NewYork-Presbyterian reported that the Moderna mRNA vaccine and a protein-based vaccine candidate containing an adjuvant, a substance that enhances immune responses, elicited durable neutralizing antibody responses to SARS-CoV-2 (..)

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Vaccine Vaccination Immune Response Containment 75

Scienmag

SEPTEMBER 18, 2020

During this ground-breaking study, scientists from the Spanish National Research Council and the University of Surrey investigated the immune response of […].

Gene 72

Gene Immune Response Scientist Research 72

pharmaphorum

JUNE 30, 2021

Just a few months after starting clinical trials of its nasal spray vaccine for COVID-19, US biotech Altimmune is abandoning the project, saying that it generated weaker than expected immune responses in a phase 1 trial. . We believe that prior immunity in humans may be important for a robust immune response to intranasal dosing.”

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Vaccine Vaccination Trials Immune Response 98

Scienmag

APRIL 19, 2021

A group of scientists have just made a key discovery that could prevent and eradicate immune responses that lead to treatment failure in about one-third of people with severe hemophilia A. Hemophilia is the most common severe inherited bleeding disorder in men.

Immune Response 72

Immune Response Scientist Medicine 72

The Pharma Data

DECEMBER 7, 2020

7, 2020 — Scientists say they may be getting closer to creating a universal flu vaccine. In an early-stage clinical trial with 65 volunteers in the United States, an experimental vaccine triggered strong immune responses to a wide range of flu virus strains and subtypes. MONDAY, Dec.

Vaccine 52

Vaccine Vaccination Scientist Immune Response 52

Scienmag

MAY 28, 2021

The drug diABZI — which activates the body’s innate immune response — was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2, according to scientists in the Perelman School of Medicine at the University of Pennsylvania.

Immune Response 71

Immune Response Drugs Scientist Research 71

Medical Xpress

MARCH 6, 2023

Scientists in Japan have revealed a chemical compound that could be used for the treatment of various autoimmune diseases like multiple sclerosis and rheumatoid arthritis. These diseases occur when the body's immune response goes awry.

Immune Response 76

Immune Response Scientist 76

The Pharma Data

JUNE 30, 2021

For their remarkable scientific contributions, doctoral student Julia Klaus, Zurich University VetSuisse Faculty, and Dr Yasmin Parr from the MRC-University of Glasgow, Centre for Virus Research, have received the 2021 ABCD Young Scientist Award. To foster young talent development in the feline health research community.

Scientist 52

Scientist Immune Response Antibody Development 52