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Ginkgo Bioworks partners with WARF for new GD2 CAR T-cell therapies

Pharmaceutical Technology

WARF is the patenting and licensing organisation for the University of Wisconsin–Madison in the US. All the new GD2 CAR designs developed through the partnership will be validated via in vitro screens and in vivo murine models. Topic sponsors are not involved in the creation of editorial content.

In-Vivo 264
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Nuvectis Pharma receives IND approval from FDA for NXP900

Pharmaceutical Technology

Nuvectis has licensed the exclusive global rights to NXP900 from the University of Edinburgh in Scotland, UK. NXP900 plus Osimertinib in vitro showed a possible ability to reverse acquired resistance to these drugs in non-small cell lung cancers. The approval also includes clearance for a Phase I clinical trial protocol of NXP900.

In-Vivo 130
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Betta to commercialise C4 Therapeutics’ CFT8919 in greater China

Pharmaceutical Technology

C4 Therapeutics has entered an exclusive licensing agreement with Betta Pharmaceuticals to develop and commercialise CFT8919 across the greater China region. Betta will be responsible for the development, manufacture and commercialisation of CFT8919 in the licensed territories.

In-Vivo 130
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Eucure Biopharma and Chipscreen NewWay sign licence deal for YH008

Pharmaceutical Technology

Biocytogen Pharmaceuticals’ wholly owned subsidiary Eucure Biopharma and Shenzhen Chipscreen Biosciences’ holding subsidiary Chipscreen NewWay Biosciences have entered an exclusive licensing agreement for YH008, a bispecific antibody. It also activated tumour-infiltrating DCs and T cells in vivo pharmacodynamic studies.

In-Vivo 130
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Could CRISPR cure HIV? US biotech Excision raises $60m to find out

pharmaphorum

The company, which has licensed the CRISPR-based technology from Philadelphia’s Temple University, says it has already produced a functional cure for HIV that works in animals and wants to develop the technology in humans. We have proven the technology and candidate programs in vitro and in vivo in both small animal models and primate models.

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Merck will assess Quris’ AI ‘patient-on-a-chip’ drug safety

pharmaphorum

Quris’ BioAI safety prediction platform – which is based on human tissue samples on chips, nanosensors and machine learning – will be compared to traditional in vitro and in vivo laboratory techniques for spotting toxicity.

Drugs 98
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ViGeneron signs global collaboration agreement for ophthalmic gene therapy development

The Pharma Data

05, 2021 (GLOBE NEWSWIRE) — ViGeneron GmbH , a gene therapy company, today announced a global collaboration and licensing agreement with Biogen Inc. Within the collaboration, ViGeneron will optimize and validate in vitro therapeutic candidates for an undisclosed target to treat inherited eye disease. MUNICH, Germany, Jan.