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Vir awarded $1 billion multi-year BARDA influenza contract

pharmaphorum

It has been shown in vitro to cover all major influenza A strains that have arisen since the 1918 ‘Spanish flu’ pandemic and is designed as a universal prophylactic for influenza A. VIR-2482 is an investigational intramuscularly administered influenza A-neutralising mAb.

Antibody 110
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Evusheld long-acting antibody combination recommended for approval in the EU for the pre-exposure prophylaxis (prevention) of COVID-19

The Pharma Data

People not adequately protected by a COVID-19 vaccine may particularly benefit from pre-exposure prophylaxis with Evusheld. People not adequately protected by a COVID-19 vaccine may particularly benefit from pre-exposure prophylaxis with Evusheld. 2-4 Evusheld was generally well-tolerated in the trial.(2-4).

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Evusheld long-acting antibody combination approved in the EU for pre-exposure prophylaxis (prevention) of COVID-19 in a broad population

The Pharma Data

Evusheld has the potential to provide long-lasting protection against COVID-19 for a broad population of individuals, including those who aren’t adequately protected by a COVID-19 vaccine, as well as those at increased risk of exposure.”. 2 subvariant, now the dominant strain in Europe. 1-3 Evusheld was generally well-tolerated in the trial.

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New analyses of two AZD7442 COVID-19 Phase III trials in high-risk populations confirm robust efficacy and long-term prevention

The Pharma Data

About 2 of the global population is considered at increased threat of an shy response to a COVID-19 vaccine.1 Importantly, six months of protection was maintained despite the swell of the Delta variant among these high- threat actors who may not respond adequately to vaccination.”.

Trials 52
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AZD7442 PROVENT Phase III prophylaxis trial met primary endpoint in.

The Pharma Data

AZD7442 is the first antibody combination (non-vaccine) modified to potentially provide long-lasting protection that has demonstrated prevention of COVID-19 in a clinical trial. More than 75% of participants had co-morbidities, which include conditions that have been reported to cause a reduced immune response to vaccination.

Trials 52
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Update on AZD7442 STORM CHASER trial in post-exposure prevention of symptomatic COVID-19

The Pharma Data

While COVID-19 vaccination efforts have been successful, there is still a significant need for prevention and treatment options for certain populations, including those unable to be vaccinated or those who may have an inadequate response to vaccination.”. The PROVENT trial will give us more clarity in this patient population.

Trials 52
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AZD7442 request for Emergency Use Authorization for COVID-19 prophylaxis filed in US

The Pharma Data

Mene Pangalos, Executive Vice President, BioPharmaceuticals R&D, AstraZeneca, said” Vulnerable populations suchlike as the immunocompromised hourly are n’t suitable to mount a self-protective response following vaccination and continue to be at trouble of developing COVID-19.