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‘In vivo’ cell therapy: expanding beyond CAR-T

Bio Pharma Dive

At least five startups have emerged with new ways to genetically modify immune cells within the body, an approach that, if successful, could widen the field of CAR-T treatment.

In-Vivo 359
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Interius Gets Go-Ahead for Phase I Trial of In Vivo CAR-T Therapy in Australia

BioSpace

Interius BioTherapeutics has received approval from Australia’s Human Research Ethics Committee to begin the first-in-human trial of an investigational in vivo CAR-T therapy designed to treat B-cell malignancies.

In-Vivo 74
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3rd In Vivo Cell Engineering & Gene Editing Summit

pharmaphorum

Achieve Safe & Targeted In Vivo Delivery of Payloads with Clarity in Regulations & Appropriate Models to Advance the Next Frontier of In Vivo Editing from Research to Clinic

In-Vivo 52
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Astellas teams up with startup Kelonia to make ‘in vivo’ cell therapies

Bio Pharma Dive

Kelonia will receive $40 million upfront through a partnership to develop “off-the-shelf” cell therapies for cancer.

In-Vivo 303
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Editas, changing course again, looks to partner lead CRISPR therapy

Bio Pharma Dive

The gene editing company will focus on “in vivo” medicines, while seeking to license out or find a development partner for its clinical-stage treatment reni-cel.

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Ensoma buys a startup to advance ‘in vivo’ cell therapy work

Bio Pharma Dive

The Takeda-backed biotech revealed it’s raised $85 million in new funding alongside announcing the acquisition of gene editing startup Twelve Bio.

In-Vivo 317
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FDA clears Intellia to start US tests of ‘in vivo’ gene editing drug

Bio Pharma Dive

The announcement, which follows recent regulatory setbacks for some of Intellia’s peers, is a “big win” for the gene editing field, according to one analyst.