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Alzheimer’s Research Shifts from Amyloid and Tau to Neuroinflammation, Other Causes

BioSpace

Research into Alzheimer’s disease is shifting from amyloid plaque and tau protein to neuroinflammation, white matter changes and insulin resistance.

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Lilly grabs glucose-sensing insulin tech, buying Protomer in $1bn deal

pharmaphorum

Eli Lilly bought a stake in Protomer Technologies and its glucose-sensing insulin platform last year, and it must like what it has seen in the programme since then – it has just agreed to buy the company outright. . It was also responsible for the first recombinant insulin product – Humulin – which launched in 1982 and remains on sale.

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Scotland Introduces First C-Peptide Type 1 Diabetes Test

XTalks

The government of Scotland has rolled out a new C-peptide test for type 1 diabetes that could help patients monitor their insulin levels with greater accuracy. The test provides information about the amount of insulin a patient has in their body, which can help determine whether they can reduce or stop taking their insulin injections.

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Study describes new way of generating insulin-producing cells

Scienmag

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis. The results are published in Nature Chemical Biology.

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Blood pressure medication shows benefits treating Type 1 diabetes

The Pharma Data

Use of the drug verapamil to treat Type 1 diabetes continues to show benefits lasting at least two years, researchers report in the journal Nature Communications. Type 1 diabetes is an autoimmune disease that causes loss of pancreatic beta cells, which produce endogenous insulin. There is no current oral treatment for this disease.

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Velocity Investigators Active at the American Diabetes Association (ADA) 83rd Scientific Sessions

Velocity Clinical Research

The prolific researchers also had findings simultaneously published in the New England Journal of Medicine and The Lancet. Dr. Rosenstock is the lead investigator for Novo Nordisk’s ONWARDS 1 program exploring the first investigational once-weekly insulin. “In Trial results were presented at the ADA sessions and published in NEJM.

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New medications for PCOS slowly edge toward development

Pharmaceutical Technology

While lifestyle modifications play a key role in treating PCOS, the paucity of new treatments signal a need for breakthrough research. Research states that PCOS is typically characterized by hyperandrogenism, high levels of androgens; ovulatory dysfunction; and polycystic ovaries.