Scienmag

JUNE 13, 2022

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis. The results are published in Nature Chemical Biology.

Insulin 50

Insulin Protein Regulation Research 50

XTalks

NOVEMBER 2, 2021

The government of Scotland has rolled out a new C-peptide test for type 1 diabetes that could help patients monitor their insulin levels with greater accuracy. The test provides information about the amount of insulin a patient has in their body, which can help determine whether they can reduce or stop taking their insulin injections.

Insulin 98

Insulin Protein Hormones Regulation 98

The Pharma Data

JULY 29, 2021

Food and Drug Administration approved the first interchangeable biosimilar insulin product, indicated to improve glycemic control in adults and pediatric patients with Type 1 diabetes mellitus and in adults with Type 2 diabetes mellitus. Semglee (insulin glargine-yfgn) is the first interchangeable biosimilar product approved in the U.S.

Insulin 52

Insulin Production FDA Approval Generic Drugs 52

Drug Patent Watch

JANUARY 13, 2025

Similarly, the European Medicines Agency (EMA) has been at the forefront of biosimilar regulation, with a well-established approval process in place since 2006. ” Diabetes: Addressing a Global Epidemic With diabetes affecting millions worldwide, the advent of biosimilar insulins has been particularly impactful.

Marketing 66

Marketing Insulin Generic Drugs Medicine 66

XTalks

MARCH 17, 2025

Amylin, a hormone co-secreted with insulin, plays a key role in regulating appetite by enhancing leptins effects the hormone that signals fullness after eating. Petrelintide, Zealand Pharmas long-acting amylin analog, is currently in Phase II clinical development and is designed for once-weekly subcutaneous injections.

Hormones 59

Hormones Drugs Sales Insulin 59

Scienmag

MAY 4, 2021

Credit: Lin-Feng Chen A new study, published in JCI Insight, looks at how Brd4, a regulator of the innate immune response, influences diet-induced obesity. The researchers believe that Brd4 could be used as a target for obesity and insulin resistance. Approximately one-third of the adults and one in five children in the U.S.

Immune Response 55

Immune Response Insulin Regulation Research 55

XTalks

JUNE 3, 2021

Researchers at the Edith Cowan University’s (ECU) Institute for Nutrition Research in Perth, Australia found that consuming at least two servings of fruit a day was linked to 36 percent lower odds of developing type 2 diabetes. A new Australian study suggests that eating fruit may lead to a reduced risk of developing type 2 diabetes.

Insulin 59

Insulin Development Research Doctor 59

Pharmaceutical Technology

MARCH 23, 2023

While lifestyle modifications play a key role in treating PCOS, the paucity of new treatments signal a need for breakthrough research. Research states that PCOS is typically characterized by hyperandrogenism, high levels of androgens; ovulatory dysfunction; and polycystic ovaries.

Development 130

Development Insulin Hormones Research 130

Pharmaceutical Technology

JANUARY 31, 2023

The US omnibus bill passed in late December 2022 will give the agency greater powers to regulate accelerated approval drugs, while the Inflation Reduction Act’s lowering of drug prices will create an uncertain environment for drug developers, he said. It’s much needed. It’s a hot area.” trillion Consolidated Appropriations Act.

Drugs 130

Drugs Gene Therapy Regulation Insulin 130

XTalks

DECEMBER 13, 2024

Petrelintide, administered once a week under the skin, targets obesity through its action as an amylin analog, a hormone co-secreted with insulin from the pancreas. Amylin helps regulate satiety and slows gastric emptying, which can support weight loss.

Drugs 102

Drugs Hormones Trials Clinical Trials 102

pharmaphorum

MAY 21, 2021

Arecor’s own lead product is an ultra-rapid acting insulin, which the company hopes will outperform market rivals from the likes of Eli Lilly, Sanofi and Novo Nordisk. Codenamed AT247, the product has a novel meal-time insulin formulation, which significantly accelerates insulin absorption post injection.

Insulin 52

Insulin Drugs Production Marketing 52

The Pharma Data

MARCH 3, 2022

Use of the drug verapamil to treat Type 1 diabetes continues to show benefits lasting at least two years, researchers report in the journal Nature Communications. Type 1 diabetes is an autoimmune disease that causes loss of pancreatic beta cells, which produce endogenous insulin. There is no current oral treatment for this disease.

Insulin 52

Insulin Gene Expression Gene Protein 52

pharmaphorum

JUNE 14, 2021

Rebecca Sanders from Lipodystrophy UK tells us how the patient voice helped convince NICE to approve a much-needed drug for this rare disease, and explores how regulators and pharma companies can help make patient involvement in HTA more impactful. The earlier HTAs, researchers and pharma companies can start that engagement the better.

Drugs 105

Drugs Pharma Companies Licensing Licensing 105

Delveinsight

AUGUST 20, 2020

regulator that had earlier told there was no requirement of an AdComm for the drug, aka, valrox, has issued a complete response (CRL) letter, which could cause a significant delay for any future approval, and canceled what would have been the first-ever approval for gene therapy in the bleeding disorder.

Gene Therapy 52

Gene Therapy Research Gene Antibody 52

XTalks

SEPTEMBER 29, 2023

Specialists emphasized the need for more comprehensive research to solidify the evidence concerning its possible toxicity. Nations were prompted to gather data regarding incidence, human prevalence and risk exposure channels to more comprehensively define the threat.

Bacterium 105

Bacterium Contamination Insulin Drugs 105

The Pharma Data

NOVEMBER 2, 2020

2, 2020 — An experimental antibody drug that targets one of the body’s key metabolism regulators may help obese people lose weight — at least briefly. Researchers found that a single injection spurred “metabolic improvements” in overweight and obese adults that lasted up to two months. MONDAY, Nov.

Antibody 52

Antibody Drugs Hormones Insulin 52

pharmaphorum

OCTOBER 2, 2020

New research shows that the COVID-19 pandemic is encouraging people to take their health into their own hands, and experts say this trend towards self-care could be a significant boon for healthcare systems – one the pharma industry should be encouraging. Self-care via TikTok.

Regulation 111

Regulation Doctor Doctors Production 111

The Pharma Data

DECEMBER 15, 2020

As the world’s first PPAR pan agonist that completed two confirmatory phase III clinical trials, Chiglitazar Sodium has shown significant and long-lasting hypoglycemic effects in a series of clinical studies, as well as other comprehensive effects including significant insulin sensitization and blood lipid regulation.

Insulin 40

Insulin Drugs Production Clinical Trials 40

XTalks

APRIL 29, 2022

Tirzepatide is a novel investigational obesity treatment that contains mimetics of two hormones that are involved in regulating appetite in a single peptide: a GIP (glucose-dependent insulinotropic polypeptide) receptor agonist and a GLP-1 (glucagon-like peptide-1) receptor agonist.

Trials 98

Trials Drugs FDA Approval Clinical Trials 98

XTalks

FEBRUARY 6, 2024

Successful biotech IPOs in 2024 have the potential to generate substantial returns for early investors and provide the crucial capital required for biotech firms to sustain and advance their research and development endeavors. Current price as of February 5 th , 2024: $11.78 CG Oncology IPO date: January 24 th , 2024 IPO price: $19.00

Gene Therapy 98

Gene Therapy Gene Clinical Trials Clinical Trials 98

XTalks

OCTOBER 11, 2023

They mimic the action of GLP-1, a hormone that helps regulate blood sugar levels by enhancing insulin secretion. There was also a high rate of biliary disease in patients taking either liraglutide or semaglutide, but the researchers said the difference was “not found to be statistically significant.”

Drugs 59

Drugs Insulin Hormones FDA Approval 59

BioSpace

JULY 3, 2022

Rather than selling, Novartis could spin Sandoz off into its own separate entity with its own listing on a stock exchange.

Marketing 40

Marketing In-Vitro Genomics Genome 40

XTalks

JANUARY 21, 2025

The tricuspid valve, one of the heart’s four valves, regulates blood flow from the right atrium to the right ventricle, preventing backflow between these chambers. Users can also manually log details such as blood glucose readings, meals, exercise or insulin doses. The device is half the size of Medtronics previous CGMs.

FDA Approval 105

FDA Approval Manufacturing Development RNA 105

The Pharma Data

JANUARY 19, 2021

19, 2021 — Tough limits on carbohydrates in your meals can help get type 2 diabetes under control — but the benefits typically wane over time, a new research review shows. It’s not clear why, according to Grant Brinkworth, one of the researchers on the review. TUESDAY, Jan. Centers for Disease Control and Prevention.

Doctor 52

Doctor Doctors Trials Insulin 52

XTalks

SEPTEMBER 28, 2023

This is because the US has more lenient food ingredient regulations, potentially exposing consumers to carcinogens and harmful chemicals. Most research, however, suggests that the amount of titanium dioxide ingested from food is minimal, posing little to no risk to human health.

Hormones 52

Hormones Containment Production Cosmetics 52

pharmaphorum

JUNE 2, 2022

This is why the action by the US in 1983 and subsequently the European Commission Regulation No. 141/2000 (the Orphan Regulation), that both acted to encourage development in the area, are regarded as crucial for changing the landscape in rare disease R&D. It is estimated that between 3.5 The price is right. Reaching a compromise.

Drugs 52

Drugs Sales Marketing Development 52

XTalks

SEPTEMBER 17, 2020

Often, the potential patient pool for a given trial is small and the unmet need is high, incentivizing drugmakers and regulators to find innovative ways to make game-changing therapeutics available to those who need them most.

Trials 98

Trials Gene Hormones Clinical Trials 98

The Pharma Data

DECEMBER 15, 2020

Researchers are aware of more than 80 diseases that occur when the immune system attacks the body’s own organs, tissues and cells. The researchers regulated the abnormal immunological memory processes found in these patients. However, if the immune system malfunctions, it can attack healthy cells, tissues and organs.

Clinical Trials 52

Clinical Trials Clinical Trials Antibody Trials 52

The Pharma Data

DECEMBER 13, 2020

AMPK is a master regulator of several important metabolic pathways, including lipid metabolism, glucose control and inflammation, and is a novel target for NASH and additional chronic and rare metabolic diseases. Harrison, MD, Director, Summit Clinical Research. . . About PXL770.

Trials 40

Trials In-Vitro Insulin Protein 40

XTalks

JUNE 12, 2023

These powerhouse organizations have not only distinguished themselves through their cutting-edge devices and technologies but also via their robust research and development (R&D) capabilities, unwavering commitment to quality and extensive global reach. It also plans to launch these products in the US.

FDA Approval 98

FDA Approval Production Sales In-Vitro 98

Scienmag

DECEMBER 3, 2020

Researchers from the University of Copenhagen and biotech firm Gubra have developed a new insulin molecule that will make blood sugar regulation both easier and safer for those with type 1 diabetes Everyday life for the more than 46 million people around the world who suffer from type 1 diabetes could become much easier and […].

Insulin 40

Insulin Regulation Development Research 40

World of DTC Marketing

JUNE 16, 2021

The May 2021 KFF Health Tracking Poll finds about two-thirds of adults say there is “not as much regulation as there should be” when it comes to limiting the price of prescription drugs. About eight in ten across partisans say profits made by pharmaceutical companies are a “major factor” in the price of prescription drugs. Emanuel .

Drugs 180

Drugs Branding Medicine Insulin 180

World of DTC Marketing

NOVEMBER 8, 2021

The plan would also place inflation caps on prescription drug prices for all insurance plans, restrict copays for insulin to no more than $35, and limit Medicare beneficiaries’ annual out-of-pocket drug costs to $2,000. More changes are coming as consumers are tired of high drug prices while pharma reports record profits.

Drugs 198

Drugs Insulin Manufacturing Regulation 198

pharmaphorum

JANUARY 24, 2023

Pharma will be focusing more on relevant research, support, and a better mix of non-promotional and promotional interaction. Medicines distribution and supply is also an energy intensive and regulated business. Medicines manufacturing is energy intensive.

Medicine 98

Medicine Manufacturing Marketing Regulation 98

XTalks

JUNE 10, 2024

Efruxifermin is a novel Fc-FGF21 fusion protein designed to emulate the activity of native FGF21, an endogenous hormone that regulates metabolism and alleviates cellular stress. Research indicates that approximately 34 percent of individuals with obesity are also affected by MASH.

Insulin 52

Insulin Life Science Regulation Hormones 52

The Pharma Data

DECEMBER 14, 2020

14, 2020 — It could be more than just added calories: New research gives insight into why sugary drinks are a leading cause of obesity. adults, and researchers now report that the drinks also hinder hormones that quell hunger and regulate appetite. MONDAY, Dec. © 2020 HealthDay.

Hormones 52

Hormones Containment Insulin Regulation 52

The Pharma Data

AUGUST 3, 2021

– Second-quarter 2021 operating expenses increased 18 percent, driven primarily by higher research and development investments for late-stage assets, as well as higher relative marketing and selling expenses due to pandemic-related spending reductions in 2020. – Second-quarter 2021 earnings per share (EPS) decreased to $1.53

Antibody 52

Antibody Sales Development Production 52